Educational information, not medical advice.See how evidence is graded

Clinically studied compounds: 512 supplements and isolates, graded by evidence

These are not a tradition. They are single compounds, isolates and modern formulations that reached use through research rather than through inheritance — melatonin, creatine, berberine, the tissue salts, the peptides. Grouping them separately keeps the tradition hubs honest, because filing a compound developed in a laboratory under the tradition of a plant it was extracted from would misdescribe both. Being here says nothing about how strong the evidence is: the grade does.

AA — consistent trial evidence91

BB — some trial evidence150

CC — limited or mixed evidence108

DD — little evidence beyond tradition64

–Insufficient evidence11

–Not yet graded88

Not every remedy names a tradition. Browse the full A–Z index for all 3,787 remedies, including the 255 with no recorded tradition.