Educational information, not medical advice.See how evidence is graded

Cascara sagrada

Early evidence for: Constipation; Bowel regularity; Occasional digestive sluggishness. Relieves constipation, supports bowel regularity.

Home

What is it?  Cascara sagrada is a type of bark from the buckthorn tree, commonly found in North America. It has been used for centuries by indigenous people as a natural laxative to treat constipation. How does it work? Cascara sagrada works by increasing the contractions of the large intestine, thereby promoting bowel movements and relieving constipation. It contains anthraquinones, which stimulate the muscles in the intestines and increase the production of mucus, helping to soften and lubricate the stool. What are the active ingredients? Active ingredients are Anthraquinones, including cascarosides and aloins. What forms does it come in? Capsules Tablets Teas Liquid extracts When was it first used for medicinal purposes? Cascara sagrada has been used by indigenous people in North America for centuries. Its use as a natural laxative was documented by Spanish explorers in the 16th century. Summary: Cascara sagrada is a natural laxative made from the bark of the buckthorn tree. It works by increasing the contractions of the large intestine to promote bowel movements. The active ingredients in cascara sagrada are anthraquinones, including cascarosides and aloins. It is available in various forms, including capsules, tablets, teas, and liquid extracts. Cascara sagrada is primarily used to treat constipation and improve bowel regularity, and may also be used to relieve bloating and abdominal discomfort associated with constipation.

Helps

What does Cascara sagrada help with? Constipation: Cascara is one of the most well-studied herbal laxatives. Its active compounds stimulate the colon to contract and move stool along, while also pulling water into the bowel to keep things soft. Most people see results within 6 to 12 hours . Chronic constipation: For people who struggle with ongoing constipation, cascara can provide reliable relief. It's best used short-term or cyclically rather than every day, since the colon can become dependent on stimulant laxatives over time. Bowel irregularity: When the digestive system is sluggish due to travel, dietary changes, or stress, cascara can help reset the rhythm. It works gently enough that it's been used across age groups in traditional settings. Sluggish digestion: Traditional herbalists used cascara not just for constipation but for a general sense of digestive heaviness or fullness. Its mild bitter properties were also thought to stimulate bile flow and support digestion more broadly. Hemorrhoid discomfort (by softening stool): Straining during bowel movements is a major driver of hemorrhoid pain and worsening. By softening stool and reducing the effort needed to go, cascara can take pressure off irritated hemorrhoidal tissue. Bowel prep before procedures: Cascara has historically been used as part of bowel preparation protocols. Its reliable stimulant effect makes it useful before colonoscopy or other procedures requiring a clean colon, though modern medical prep solutions are now more common. Occasional bloating from backed-up stool: When bloating is caused by slow transit and stool buildup rather than gas alone, moving things along with cascara can bring quick relief. It addresses the root cause — stool not moving — rather than just treating the sensation. Liver and gallbladder sluggishness (traditional use): Traditional herbalists in both Indigenous American and later Western herbal medicine used cascara as a tonic for the liver and gallbladder, believing it supported bile production and fat digestion. This use is not well-studied in modern clinical trials but has a long historical record.

Cascara sagrada

Cascara sagrada

Quick Facts

  • What it is: A bark from a tree native to the Pacific Northwest, used for centuries by Indigenous peoples as a gentle but effective laxative.
  • Main uses: Relieves constipation, supports bowel regularity, and is sometimes used for short-term digestive sluggishness.
  • Best for: Constipation, Bowel regularity, Occasional digestive sluggishness
  • Active ingredients: Cascarosides A, B, C, D, Emodin, Aloe-emodin, Anthraquinone glycosides, Barbaloin
  • Forms: Capsule, Liquid extract, Tincture, Dried bark (tea), Tablet
  • Time to effect: 6 to 12 hours after taking
  • Side effects: Generally safe for short-term use, but can cause cramping, diarrhea, or electrolyte imbalances if used too long or at high doses.
  • Pregnancy & breastfeeding: Not assessed for this entry. Ask your doctor or midwife before use.

Educational information, not medical advice — ask your doctor or midwife.

What is it? 

Cascara sagrada is a type of bark from the buckthorn tree, commonly found in North America. It has been used for centuries by indigenous people as a natural laxative to treat constipation.

How does it work?

Cascara sagrada works by increasing the contractions of the large intestine, thereby promoting bowel movements and relieving constipation. It contains anthraquinones, which stimulate the muscles in the intestines and increase the production of mucus, helping to soften and lubricate the stool.

What are the active ingredients?

Active ingredients are Anthraquinones, including cascarosides and aloins.

What forms does it come in?

  • Capsules
  • Tablets
  • Teas
  • Liquid extracts

When was it first used for medicinal purposes?

Cascara sagrada has been used by indigenous people in North America for centuries. Its use as a natural laxative was documented by Spanish explorers in the 16th century.

Summary:

Cascara sagrada is a natural laxative made from the bark of the buckthorn tree. It works by increasing the contractions of the large intestine to promote bowel movements. The active ingredients in cascara sagrada are anthraquinones, including cascarosides and aloins. It is available in various forms, including capsules, tablets, teas, and liquid extracts. Cascara sagrada is primarily used to treat constipation and improve bowel regularity, and may also be used to relieve bloating and abdominal discomfort associated with constipation.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

Remedies related to Cascara sagrada

People take Cascara sagrada when they say

Everyday descriptions of the problems this remedy is recommended for.

Conditions where Cascara sagrada is recommended

Each grade below is for that condition specifically, not for Cascara sagrada in general.

Natural options for Chronic Constipation, ranked by evidence

The 7 options with the best evidence for Chronic Constipation, each with its grade and who should avoid it. One email.

Occasional evidence updates after that — unsubscribe any time.