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Educational information, not medical advice — ask your doctor or midwife.
Jamaican Dogwood (Piscidia piscipula) is a medium-sized tree native to the Caribbean, Central America, and southern Florida. Its root bark has a long history of use in indigenous and folk medicine as a powerful sedative, analgesic, and antispasmodic. It was so effective at stunning fish that local fishermen would throw bark preparations into the water to make fish easy to catch — a practice that earned it the nickname 'Fish Poison Tree.'
Jamaican Dogwood appears to calm the nervous system by reducing the excitability of nerve signals, which helps quiet pain and ease muscle tension. Its isoflavone compounds also have mild sedative effects and may gently promote relaxation by acting on pathways similar to those targeted by conventional sleep and anxiety medications — but with a gentler touch. It also has antispasmodic properties that help relax smooth and skeletal muscle.
Tincture (liquid extract) is the most traditional and widely used form, offering quick absorption and flexible dosing. Capsules and standardized extracts are more convenient for daily use. Dried root bark can be prepared as a tea or decoction, though the taste is quite bitter. Fluid extracts used by herbalists are typically more concentrated than tinctures.
Indigenous Caribbean and Central American peoples used Jamaican Dogwood root bark for toothache, nerve pain, and insomnia long before European contact. It was adopted by Eclectic physicians in 19th-century America as a remedy for neuralgia, dysmenorrhea, and whooping cough, and was listed in early editions of the US National Formulary. It remains a respected herb in Western herbal medicine traditions today.
Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.
Reviewed by the HealisticMD editorial team How we grade evidence →
The published evidence for Jamaican Dogwood is weak or absent. That usually means no controlled trial has tested it, not that a trial found it ineffective — the two are different, and we grade only what has been published.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
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