Conditions in this group
Best-supported options
Ranked by the strength of human research, strongest first. A grade describes the evidence, not how well something will work for you.
- AshwagandhaAStrong evidenceBest known for lowering stress and anxiety, supporting testosterone and energy levels, improving sleep quality, and building physical endurance.Safety: caution — read the full safety section before use
- CurcuminAStrong evidenceBest known for calming inflammation, easing joint pain, supporting brain health, and helping the body manage oxidative stress.Safety: caution — read the full safety section before use
- ZincAStrong evidenceSupports immune defense, wound healing, testosterone production, skin health, and sharp senses of taste and smell.Safety: caution — read the full safety section before use
- BerberineAStrong evidenceBest known for lowering blood sugar, improving insulin sensitivity, and supporting healthy cholesterol and weight.Safety: caution — read the full safety section before use
- Vitamin DAStrong evidenceSupports bone strength, immune defense, mood, muscle function, and may reduce the risk of several chronic diseases.Safety: caution — read the full safety section before use
- Alpha-Lipoic Acid (ALA)AStrong evidenceBest known for protecting nerves in people with diabetes, lowering blood sugar, and fighting oxidative stress throughout the body.Safety: caution — read the full safety section before use
- BiofeedbackAStrong evidenceMost widely used for stress, anxiety, chronic pain, migraines, and high blood pressure.
- BoswelliaAStrong evidenceBest known for reducing joint pain and stiffness, supporting gut health, and easing breathing in inflammatory conditions.Safety: caution — read the full safety section before use
Traditional use in this group
Used in a healing tradition for this group of conditions. These carry no evidence grade — they have not been shown to work in human trials, and are listed because people look for them, not as a recommendation.
Pressure points used for these conditions
Acupressure points traditionally used for the conditions in this group. Each point page sets out what the evidence for it does and does not show.
- CV4 (Guanyuan) - Conception Vessel 4CV4, also known as "Guanyuan" or the “Gate of Origin,” is a vital acupressure and acupuncture point located on the Conception Vessel meridian.
- BL23 (Shenshu) - Bladder 23 BL23, also known as "Shenshu" or the “Kidney Shu,” is a critical acupuncture and acupressure point located on the Bladder meridian.
- SP6 (Sanyinjiao) - Spleen 6Located on the inner side of the lower leg, approximately three finger-widths above the inner ankle bone, SP6 is where the Spleen, Liver, and Kidney meridians intersect.
- DU4 (Mingmen) - Governing Vessel 4DU4, also known as "Mingmen" or the “Gate of Life,” is a significant acupuncture and acupressure point located on the Governing Vessel meridian.
- GB20 (Fengchi) - Gallbladder 20GB20, also known as "Fengchi" or “Wind Pool,” is an important acupressure and acupuncture point located at the base of the skull, in the hollows on either side of the neck.
- KD3 (Taixi) - Kidney 3It is located just above the inner ankle bone, in the depression between the ankle bone and the Achilles tendon.
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Reviewed by the HealisticMD editorial team How we grade evidence →