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Quercetin
Quick Facts
- What it is: Quercetin is a plant pigment (flavonoid) found in many fruits, vegetables, and herbs — one of the most abundant antioxidants in the human diet.
- Main uses: Most used for allergy relief, reducing inflammation, supporting heart health, and bolstering immune defense.
- Best for: Seasonal allergies, Chronic inflammation, Heart health
- Active ingredients: Quercetin (aglycone), Quercetin glycosides (e.g., isoquercetin, rutin), Quercetin phytosome (complexed with phosphatidylcholine for enhanced absorption)
- Forms: Capsule, Tablet, Powder, Softgel (phytosome form), Liquid extract, Chewable
- Time to effect: Allergy and inflammation relief: 1–4 weeks; antioxidant and cardiovascular benefits: 6–12 weeks of consistent use.
- Side effects: Generally very well tolerated at standard doses; high doses may occasionally cause headache or tingling sensations.
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What is quercetin?
Quercetin is a flavonoid, a type of antioxidant commonly found in plants, fruits, and vegetables. It has gained attention for its potential health benefits, particularly in reducing inflammation and protecting against chronic diseases.
How does it work?
Quercetin has been shown to have various beneficial effects on human health, including its ability to reduce oxidative stress and inflammation, as well as its potential to prevent and treat certain chronic diseases. It is believed to work by inhibiting certain enzymes and pathways involved in inflammation and oxidative stress.
What are the active ingredients that are important for its medicinal properties?
Quercetin is the active ingredient responsible for its medicinal properties.
What forms does it come in?
Quercetin is available in supplement form, as well as in various foods such as onions, apples, berries, and tea.
When was it first used for medicinal purposes?
Quercetin has been used in traditional medicine for centuries, particularly in Asian cultures, to treat various ailments.
Who should avoid Quercetin?
- Do not take quercetin with cyclosporine (a drug that stops organ rejection) unless your doctor approves it.
- Do not take quercetin with warfarin (a blood thinner) unless your doctor is watching your clotting tests.
- Avoid quercetin while you are on a quinolone antibiotic such as ciprofloxacin.
- Do not start quercetin without asking your doctor if you take any daily prescription drug for your heart, blood or immune system.
- Do not take more than 1000 mg a day on your own, since higher doses are not well studied.
- Never take gram-size doses for many months in a row without a doctor checking in.
- Do not take high doses if you have kidney disease or only one kidney.
- Do not take high doses for months if you have a thyroid problem or take thyroid medicine.
- Stop taking quercetin if your hands or feet start to tingle, and call your doctor.
- Do not take quercetin powder on an empty stomach; always take it with food.
- Avoid quercetin supplements if you are pregnant or breastfeeding, since safe use is not known.
- Do not give quercetin supplements to a child unless a doctor tells you to.
When should you see a doctor?
Stop taking quercetin and call your doctor if your hands or feet tingle. Call also if you get a headache that will not go away. Changes in how much you pee need a same-day call.
Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.
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