Educational information, not medical advice.See how evidence is graded

Chrysin

Traditionally used for: Low testosterone support; Anxiety and stress; Inflammation. Most commonly explored for hormone balance in men, anxiety relief.

Home

What is Chrysin? Chrysin is a natural flavonoid that is found in plants such as passionflower, honey, and some species of mushrooms. It is commonly used as a dietary supplement for its potential health benefits. How does it work? Chrysin is believed to have anti-inflammatory and antioxidant properties. It may also have the ability to increase the production of certain hormones in the body, such as testosterone. However, more research is needed to fully understand its mechanisms of action. What forms does it come in? Chrysin is available in various forms, including capsules, powders, and creams.

Helps

What does Chrysin help with? Chrysin is a flavonoid, a plant compound. It turns up in honey, bee propolis and passionflower. It is sold most often in men's hormone formulas, and in some calming and sports products. Low testosterone in men Evidence doesn't support this — human trials described as modest and mixed, with no sizes or doses on file. In lab work, chrysin slows aromatase, the enzyme that turns some testosterone into estrogen. Human trial results have been modest and mixed. It is still one of the most studied natural aromatase blockers sold without a prescription. Evidence grade D · Traditional tier T0 Feeling anxious or stressed Evidence doesn't support this — early research only, plus long traditional use in passionflower calming remedies. Early research reported mild calming effects. In lab studies, chrysin acted on GABA receptors, where some anti-anxiety drugs also act. Human evidence stays limited, and our file names no trial. Evidence grade D · Traditional tier T0 Ongoing low-grade inflammation and joint pain Not yet tested in people — lab and animal studies; no large human trial on file. Chrysin is a flavonoid. In lab and animal work, it turned down inflammatory signals. Large human trials for joint pain are not on file. Evidence grade insufficient · Traditional tier T0 Protecting cells from free radicals Not yet tested in people — laboratory tests only. In lab tests, chrysin mopped up free radicals well. Most flavonoids share this trait. What that means for people has been hard to pin down. Evidence grade insufficient · Traditional tier T0 High estrogen in men Not yet tested in people — theory and lab work; no human trial on file. The theory is that blocking aromatase cuts the change from androgens to estrogens. That is reasoning, not a human result. Many men's formulas add piperine to help chrysin absorb better. Evidence grade insufficient · Traditional tier T0 Blood sugar swings Not yet tested in people — animal models mainly; very limited human data. In animal studies, chrysin improved insulin response and blunted blood sugar spikes. Human evidence is very limited. Other flavonoids show a similar early pattern. Evidence grade insufficient · Traditional tier T0 Thyroid support Not yet tested in people — early-stage research; not established in clinical trials. Some research hints at a mild effect on how the body handles thyroid hormone. This work is early stage. Clinical trials have not backed it, though some thyroid formulas still include chrysin. Evidence grade insufficient · Traditional tier T0 Recovery after hard training Not yet tested in people — product rationale only; no direct human evidence on file. Some sports products add chrysin. The reasoning leans on its anti-inflammatory and hormone claims. Direct human evidence for faster recovery is thin. Evidence grade insufficient · Traditional tier T0 What Chrysin has not been shown to do Human trials have not shown that chrysin reliably raises testosterone in men; results were modest and mixed. No human trial on file shows that chrysin lowers estrogen in men. It has not been shown to ease joint pain in people. Its lab antioxidant activity has not been shown to give a health benefit in people. It has not been shown to speed recovery after training. It has not been shown in clinical trials to shift thyroid hormone levels. It has not been shown to lower blood sugar in people. It has not been shown to work in place of prescription anti-anxiety medicine. How to read this: The grades run from A down to insufficient. A means many human trials agree. B means one good human trial. C means small or mixed human studies. D means the human evidence is weak or clashing. Insufficient means no human study at all, just lab work, animal work or tradition. This page lists options, not advice, and it is not a promise of results. Talk with your doctor before you try chrysin, above all if you take hormone or thyroid medicine.

Chrysin

Quick Facts

  • What it is: Chrysin is a naturally occurring flavonoid found in honey, propolis, and certain plants, studied mainly for its potential to support testosterone levels and reduce inflammation.
  • Main uses: Most commonly explored for hormone balance in men, anxiety relief, and antioxidant support.
  • Best for: Low testosterone support, Anxiety and stress, Inflammation
  • Active ingredients: 5,7-Dihydroxyflavone (Chrysin)
  • Forms: Capsule, Tablet, Topical cream, Raw propolis/honey
  • Time to effect: 4–8 weeks for hormonal effects; antioxidant and anti-inflammatory benefits may appear sooner.
  • Side effects: Generally well tolerated at typical doses, though high amounts may interact with certain medications.
  • Pregnancy & breastfeeding: Not assessed for this entry. Ask your doctor or midwife before use.

Educational information, not medical advice — ask your doctor or midwife.

What is Chrysin?

Chrysin is a natural flavonoid that is found in plants such as passionflower, honey, and some species of mushrooms. It is commonly used as a dietary supplement for its potential health benefits.


How does it work?

Chrysin is believed to have anti-inflammatory and antioxidant properties. It may also have the ability to increase the production of certain hormones in the body, such as testosterone. However, more research is needed to fully understand its mechanisms of action.


What forms does it come in?

Chrysin is available in various forms, including capsules, powders, and creams.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

Reviewed by the HealisticMD editorial team How we grade evidence →

Remedies related to Chrysin

The evidence behind this remedy, in one page

What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.

One email with the summary. We'll also send a short weekly evidence update — unsubscribe any time.