Premenstrual Dysphoric Disorder (PMDD): In the days before my period, how does my PMDD hit hardest?

Commonly suggested options include acupuncture, LV3 (Taichong), magnesium Deficiency, myo-Inositol, vitamin B6 (Pyridoxine) Deficiency and saffron (Crocus sativus).

Premenstrual Dysphoric Disorder (PMDD): What kind of approach would I actually stick with?

Commonly suggested options include acupuncture, LV3 (Taichong), SP6 (Sanyinjiao) - Spleen 6, vitex (Chasteberry), kamishoyosan and saffron (Crocus sativus).

Premenstrual Dysphoric Disorder (PMDD): natural remedies and the evidence behind them

11 options · 2 graded B · 2 graded C · 7 traditional or ungraded

In the days before my period, how does my PMDD hit hardest?

Anxiety, tension, or a heavy sense of dread that builds all week

Acupuncture
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
Preliminary clinical support for PMDD anxiety and mood
Why this matches
A single small RCT studied acupuncture's effects on anxiety and depression symptoms in PMDD, so early findings are relevant but not conclusive.
Why try it
Acupuncture is thought to help regulate the nervous system and stress-response pathways that amplify premenstrual anxiety and tension.
Dose or use
Sessions are typically scheduled by a licensed acupuncturist; treatment frequency and point selection will be tailored to your cycle.
Time to results
Typically 2–3 menstrual cycles
Key study
RCT (2013, PMID 24029029): Effects of acupuncture on the symptoms of anxiety and depression caused by premenstrual dysphoric disorder.
Caution
Seek a licensed practitioner; generally safe when performed correctly.
LV3 (Taichong)
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Liver-channel point traditionally used to calm tension
Why this matches
That heavy, keyed-up sense of dread maps closely to what TCM calls stagnant liver energy — LV3 is the point traditionally pressed to release premenstrual irritability and tension.
Why try it
LV3 sits on the Liver channel and is traditionally used to ease stress, anxiety, and the wound-up feeling that can peak before your period.
Dose or use
Find the spot on top of the foot, in the soft valley between the big toe and second toe. Press firmly with your thumb for 1–2 minutes on each foot while breathing slowly.
Time to results
Can feel calming within minutes; used regularly across the luteal phase
Key study
Traditionally used in acupressure for premenstrual stress and irritability; this specific self-applied use has not been confirmed in controlled clinical trials.
Caution
Press gently if the area feels tender or bruised. Not a substitute for care if anxiety becomes severe or persistent.
Magnesium Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low magnesium can heighten tension and unease
Why this matches
That tight, anxious, on-edge feeling can be intensified when magnesium is low, since your nerves and muscles rely on it to stay relaxed.
Why try it
Magnesium helps calm nerve signaling and muscle tension, and low levels are commonly associated with premenstrual anxiety, restlessness, and poor sleep.
Dose or use
Consider your magnesium intake with your provider. Food sources include leafy greens, nuts, seeds, beans, and whole grains; supplements are available if intake is low.
Time to results
Repletion effects, if any, typically build over 1–3 cycles
Key study
Recognized nutrient-deficiency link; surfaced as background context rather than from a trial of correcting deficiency in PMDD specifically.
Caution
Magnesium supplements can cause loose stools at higher doses and may interact with certain medications; check with your provider, especially if you have kidney issues.

Low mood, sadness, or wanting to withdraw from everyone

Acupuncture
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
Preliminary clinical support for PMDD anxiety and mood
Why this matches
A single small RCT studied acupuncture's effects on anxiety and depression symptoms in PMDD, so early findings are relevant but not conclusive.
Why try it
Acupuncture is thought to help regulate the nervous system and stress-response pathways that amplify premenstrual anxiety and tension.
Dose or use
Sessions are typically scheduled by a licensed acupuncturist; treatment frequency and point selection will be tailored to your cycle.
Time to results
Typically 2–3 menstrual cycles
Key study
RCT (2013, PMID 24029029): Effects of acupuncture on the symptoms of anxiety and depression caused by premenstrual dysphoric disorder.
Caution
Seek a licensed practitioner; generally safe when performed correctly.
Myo-Inositol
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Clinically studied for PMDD depressive symptoms
Why this matches
The clinical study on myo-inositol for PMDD highlighted its relevance for the mood and depressive components of the disorder.
Why try it
Myo-inositol is a naturally occurring compound involved in serotonin signaling pathways, which are closely tied to low mood in PMDD.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 2–3 menstrual cycles
Key study
RCT (2011, PMID 22031267): Myo-inositol in the treatment of premenstrual dysphoric disorder.
Caution
Generally well tolerated; consult your provider if you take psychiatric medications.
Vitamin B6 (Pyridoxine) Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low B6 can worsen premenstrual irritability
Why this matches
Feeling out of control in your mood can be amplified when B6 runs low, because your body needs it to make the mood-steadying brain chemicals serotonin, dopamine, and GABA.
Why try it
Vitamin B6 is a cofactor your body uses to build the neurotransmitters that regulate mood, and low levels are a well-known contributor to premenstrual irritability and low mood.
Dose or use
Worth discussing your B6 status with your provider. Food sources include poultry, fish, chickpeas, bananas, and potatoes; if supplementing, keep to modest doses under guidance.
Time to results
Repletion effects, if any, typically build over 1–3 cycles
Key study
Recognized nutrient-deficiency link; surfaced as background context rather than from a trial of correcting deficiency in PMDD specifically.
Caution
High-dose B6 taken long-term can cause nerve tingling or numbness. Do not exceed recommended amounts without medical supervision.
Saffron (Crocus sativus)
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Traditionally used to lift mood and ease sadness
Why this matches
Saffron has a long traditional history of use for emotional low points, pairing naturally with the low-mood and withdrawn feelings of PMDD.
Why try it
Traditionally used to support emotional well-being and ease feelings of sadness, saffron is thought to gently influence mood-related pathways.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
Caution
High doses should be avoided in pregnancy; may interact with antidepressants.

Mood swings and irritability — I snap at people and feel out of control

Vitex (Chasteberry)
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Among the most-studied herbal options for PMDD
Why this matches
Irritability and mood swings are core PMDD symptoms examined in the systematic review of Vitex, though the underlying trials were mostly in PMS and of mixed quality.
Why try it
Vitex is thought to act on dopamine receptors and help modulate the hormonal fluctuations that drive luteal-phase mood instability.
Dose or use
Typically 20–40 mg dry extract (standardized) once daily in the morning; follow product labeling for your specific extract.
Time to results
Typically 2–3 menstrual cycles
Key study
Systematic review (2017, PMID 29063202): Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review.
Caution
May interact with hormonal contraceptives or dopamine-related medications; avoid in pregnancy.
Kamishoyosan
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Traditional formula studied for broad PMDD symptoms
Why this matches
As a multi-herb formula, Kamishoyosan was piloted for the wide range of PMDD symptoms, making it a fit for those experiencing a mix.
Why try it
This traditional Japanese herbal formula is used to address emotional and physical premenstrual symptoms through a multi-ingredient approach.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 2–3 menstrual cycles
Key study
Clinical trial (2007, PMID 17472603): Effectiveness of kamishoyosan for premenstrual dysphoric disorder: open-labeled pilot study.
Caution
Evidence is preliminary (pilot study only); consult a practitioner familiar with Japanese herbal medicine.
Vitamin B6 (Pyridoxine) Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low B6 can worsen premenstrual irritability
Why this matches
Feeling out of control in your mood can be amplified when B6 runs low, because your body needs it to make the mood-steadying brain chemicals serotonin, dopamine, and GABA.
Why try it
Vitamin B6 is a cofactor your body uses to build the neurotransmitters that regulate mood, and low levels are a well-known contributor to premenstrual irritability and low mood.
Dose or use
Worth discussing your B6 status with your provider. Food sources include poultry, fish, chickpeas, bananas, and potatoes; if supplementing, keep to modest doses under guidance.
Time to results
Repletion effects, if any, typically build over 1–3 cycles
Key study
Recognized nutrient-deficiency link; surfaced as background context rather than from a trial of correcting deficiency in PMDD specifically.
Caution
High-dose B6 taken long-term can cause nerve tingling or numbness. Do not exceed recommended amounts without medical supervision.

The whole package — mood, anxiety, plus cramps, bloating, and body symptoms

Kamishoyosan
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Traditional formula studied for broad PMDD symptoms
Why this matches
As a multi-herb formula, Kamishoyosan was piloted for the wide range of PMDD symptoms, making it a fit for those experiencing a mix.
Why try it
This traditional Japanese herbal formula is used to address emotional and physical premenstrual symptoms through a multi-ingredient approach.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 2–3 menstrual cycles
Key study
Clinical trial (2007, PMID 17472603): Effectiveness of kamishoyosan for premenstrual dysphoric disorder: open-labeled pilot study.
Caution
Evidence is preliminary (pilot study only); consult a practitioner familiar with Japanese herbal medicine.
Calcium Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low calcium is linked to broad PMS symptoms
Why this matches
When mood, anxiety, and physical symptoms all pile up, calcium status is worth a look — low calcium across the luteal phase is tied to the full spread of premenstrual complaints.
Why try it
Calcium status shifts across the menstrual cycle, and low levels are associated with premenstrual mood and physical symptoms, making it a sensible thing to check when symptoms are broad.
Dose or use
Discuss your calcium and vitamin D intake with your provider. Food sources include dairy, fortified plant milks, leafy greens, and tofu.
Time to results
Repletion effects, if any, typically build over 1–3 cycles
Key study
Recognized nutrient-deficiency link; surfaced as background context rather than from a trial of correcting deficiency in PMDD specifically.
Caution
Excess calcium from supplements can cause constipation and, at high doses, other risks; aim to meet needs through food first and supplement only as advised.
SP6 (Sanyinjiao) - Spleen 6
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Go-to acupressure point for PMS symptoms
Why this matches
When everything hits at once, SP6 is the point traditionally reached for first — it is used to ease the whole cluster of premenstrual complaints, from cramps and bloating to mood swings and tension.
Why try it
In Traditional Chinese Medicine, SP6 sits where the Spleen, Liver, and Kidney channels meet, and is traditionally used to settle the physical and emotional symptoms that build in the days before your period.
Dose or use
Find the spot about four finger-widths above the inner ankle bone, just behind the shin bone. Press firmly with your thumb for 1–2 minutes on each leg, breathing slowly. Avoid during pregnancy.
Time to results
May ease tension within minutes; used across cycles for fuller effect
Key study
Traditionally used in acupressure for premenstrual symptoms; this specific self-applied use has not been confirmed in controlled clinical trials.
Caution
Do not stimulate SP6 during pregnancy, as it is traditionally associated with uterine activity. Press gently if the area is sore.
Calcium Carbonate
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
A simple, well-tolerated option for broad PMS symptoms
Why this matches
When everything hits at once, supplemental calcium is a gentle, broad option often used to take the edge off both the mood and physical sides of premenstrual symptoms.
Why try it
Calcium carbonate is a common, inexpensive form of supplemental calcium traditionally used to support premenstrual comfort across mood and physical symptoms.
Dose or use
Follow product labeling; calcium carbonate is best absorbed when taken with food. Discuss the right amount with your provider, ideally alongside adequate vitamin D.
Time to results
Typically assessed over 2–3 menstrual cycles
Key study
Traditionally used for premenstrual symptoms; this specific product's use has not been tied to a controlled clinical trial in the material provided here.
Caution
Can cause constipation, gas, or bloating; may reduce absorption of some medications, so separate dosing and check with your provider if you take other drugs.

What kind of approach would I actually stick with?

Hands-on relief — acupressure I can do myself or acupuncture from a pro

Acupuncture
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
Preliminary clinical support for PMDD anxiety and mood
Why this matches
A single small RCT studied acupuncture's effects on anxiety and depression symptoms in PMDD, so early findings are relevant but not conclusive.
Why try it
Acupuncture is thought to help regulate the nervous system and stress-response pathways that amplify premenstrual anxiety and tension.
Dose or use
Sessions are typically scheduled by a licensed acupuncturist; treatment frequency and point selection will be tailored to your cycle.
Time to results
Typically 2–3 menstrual cycles
Key study
RCT (2013, PMID 24029029): Effects of acupuncture on the symptoms of anxiety and depression caused by premenstrual dysphoric disorder.
Caution
Seek a licensed practitioner; generally safe when performed correctly.
LV3 (Taichong)
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Liver-channel point traditionally used to calm tension
Why this matches
That heavy, keyed-up sense of dread maps closely to what TCM calls stagnant liver energy — LV3 is the point traditionally pressed to release premenstrual irritability and tension.
Why try it
LV3 sits on the Liver channel and is traditionally used to ease stress, anxiety, and the wound-up feeling that can peak before your period.
Dose or use
Find the spot on top of the foot, in the soft valley between the big toe and second toe. Press firmly with your thumb for 1–2 minutes on each foot while breathing slowly.
Time to results
Can feel calming within minutes; used regularly across the luteal phase
Key study
Traditionally used in acupressure for premenstrual stress and irritability; this specific self-applied use has not been confirmed in controlled clinical trials.
Caution
Press gently if the area feels tender or bruised. Not a substitute for care if anxiety becomes severe or persistent.
SP6 (Sanyinjiao) - Spleen 6
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Go-to acupressure point for PMS symptoms
Why this matches
When everything hits at once, SP6 is the point traditionally reached for first — it is used to ease the whole cluster of premenstrual complaints, from cramps and bloating to mood swings and tension.
Why try it
In Traditional Chinese Medicine, SP6 sits where the Spleen, Liver, and Kidney channels meet, and is traditionally used to settle the physical and emotional symptoms that build in the days before your period.
Dose or use
Find the spot about four finger-widths above the inner ankle bone, just behind the shin bone. Press firmly with your thumb for 1–2 minutes on each leg, breathing slowly. Avoid during pregnancy.
Time to results
May ease tension within minutes; used across cycles for fuller effect
Key study
Traditionally used in acupressure for premenstrual symptoms; this specific self-applied use has not been confirmed in controlled clinical trials.
Caution
Do not stimulate SP6 during pregnancy, as it is traditionally associated with uterine activity. Press gently if the area is sore.

Herbal remedies with a long track record — I like plant-based options

Vitex (Chasteberry)
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Among the most-studied herbal options for PMDD
Why this matches
Irritability and mood swings are core PMDD symptoms examined in the systematic review of Vitex, though the underlying trials were mostly in PMS and of mixed quality.
Why try it
Vitex is thought to act on dopamine receptors and help modulate the hormonal fluctuations that drive luteal-phase mood instability.
Dose or use
Typically 20–40 mg dry extract (standardized) once daily in the morning; follow product labeling for your specific extract.
Time to results
Typically 2–3 menstrual cycles
Key study
Systematic review (2017, PMID 29063202): Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review.
Caution
May interact with hormonal contraceptives or dopamine-related medications; avoid in pregnancy.
Kamishoyosan
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Traditional formula studied for broad PMDD symptoms
Why this matches
As a multi-herb formula, Kamishoyosan was piloted for the wide range of PMDD symptoms, making it a fit for those experiencing a mix.
Why try it
This traditional Japanese herbal formula is used to address emotional and physical premenstrual symptoms through a multi-ingredient approach.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 2–3 menstrual cycles
Key study
Clinical trial (2007, PMID 17472603): Effectiveness of kamishoyosan for premenstrual dysphoric disorder: open-labeled pilot study.
Caution
Evidence is preliminary (pilot study only); consult a practitioner familiar with Japanese herbal medicine.
Saffron (Crocus sativus)
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Traditionally used to lift mood and ease sadness
Why this matches
Saffron has a long traditional history of use for emotional low points, pairing naturally with the low-mood and withdrawn feelings of PMDD.
Why try it
Traditionally used to support emotional well-being and ease feelings of sadness, saffron is thought to gently influence mood-related pathways.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
Caution
High doses should be avoided in pregnancy; may interact with antidepressants.

A simple daily supplement I can take with breakfast and forget about

Myo-Inositol
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Clinically studied for PMDD depressive symptoms
Why this matches
The clinical study on myo-inositol for PMDD highlighted its relevance for the mood and depressive components of the disorder.
Why try it
Myo-inositol is a naturally occurring compound involved in serotonin signaling pathways, which are closely tied to low mood in PMDD.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 2–3 menstrual cycles
Key study
RCT (2011, PMID 22031267): Myo-inositol in the treatment of premenstrual dysphoric disorder.
Caution
Generally well tolerated; consult your provider if you take psychiatric medications.
Calcium Carbonate
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
A simple, well-tolerated option for broad PMS symptoms
Why this matches
When everything hits at once, supplemental calcium is a gentle, broad option often used to take the edge off both the mood and physical sides of premenstrual symptoms.
Why try it
Calcium carbonate is a common, inexpensive form of supplemental calcium traditionally used to support premenstrual comfort across mood and physical symptoms.
Dose or use
Follow product labeling; calcium carbonate is best absorbed when taken with food. Discuss the right amount with your provider, ideally alongside adequate vitamin D.
Time to results
Typically assessed over 2–3 menstrual cycles
Key study
Traditionally used for premenstrual symptoms; this specific product's use has not been tied to a controlled clinical trial in the material provided here.
Caution
Can cause constipation, gas, or bloating; may reduce absorption of some medications, so separate dosing and check with your provider if you take other drugs.

Getting to the root cause — check whether a nutrient gap is fueling my symptoms

Calcium Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low calcium is linked to broad PMS symptoms
Why this matches
When mood, anxiety, and physical symptoms all pile up, calcium status is worth a look — low calcium across the luteal phase is tied to the full spread of premenstrual complaints.
Why try it
Calcium status shifts across the menstrual cycle, and low levels are associated with premenstrual mood and physical symptoms, making it a sensible thing to check when symptoms are broad.
Dose or use
Discuss your calcium and vitamin D intake with your provider. Food sources include dairy, fortified plant milks, leafy greens, and tofu.
Time to results
Repletion effects, if any, typically build over 1–3 cycles
Key study
Recognized nutrient-deficiency link; surfaced as background context rather than from a trial of correcting deficiency in PMDD specifically.
Caution
Excess calcium from supplements can cause constipation and, at high doses, other risks; aim to meet needs through food first and supplement only as advised.
Magnesium Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low magnesium can heighten tension and unease
Why this matches
That tight, anxious, on-edge feeling can be intensified when magnesium is low, since your nerves and muscles rely on it to stay relaxed.
Why try it
Magnesium helps calm nerve signaling and muscle tension, and low levels are commonly associated with premenstrual anxiety, restlessness, and poor sleep.
Dose or use
Consider your magnesium intake with your provider. Food sources include leafy greens, nuts, seeds, beans, and whole grains; supplements are available if intake is low.
Time to results
Repletion effects, if any, typically build over 1–3 cycles
Key study
Recognized nutrient-deficiency link; surfaced as background context rather than from a trial of correcting deficiency in PMDD specifically.
Caution
Magnesium supplements can cause loose stools at higher doses and may interact with certain medications; check with your provider, especially if you have kidney issues.
Vitamin B6 (Pyridoxine) Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low B6 can worsen premenstrual irritability
Why this matches
Feeling out of control in your mood can be amplified when B6 runs low, because your body needs it to make the mood-steadying brain chemicals serotonin, dopamine, and GABA.
Why try it
Vitamin B6 is a cofactor your body uses to build the neurotransmitters that regulate mood, and low levels are a well-known contributor to premenstrual irritability and low mood.
Dose or use
Worth discussing your B6 status with your provider. Food sources include poultry, fish, chickpeas, bananas, and potatoes; if supplementing, keep to modest doses under guidance.
Time to results
Repletion effects, if any, typically build over 1–3 cycles
Key study
Recognized nutrient-deficiency link; surfaced as background context rather than from a trial of correcting deficiency in PMDD specifically.
Caution
High-dose B6 taken long-term can cause nerve tingling or numbness. Do not exceed recommended amounts without medical supervision.

Evidence grades describe the strength of published research for Premenstrual Dysphoric Disorder (PMDD), not a promise of results. Nothing here is medical advice — talk to your clinician before starting anything, especially alongside prescription medication.

In the days before my period, how does my PMDD hit hardest?

Anxiety, tension, or a heavy sense of dread that builds all week

LV3 (Taichong)

Magnesium Deficiency

Low mood, sadness, or wanting to withdraw from everyone

Vitamin B6 (Pyridoxine) Deficiency

Mood swings and irritability — I snap at people and feel out of control

Vitamin B6 (Pyridoxine) Deficiency

The whole package — mood, anxiety, plus cramps, bloating, and body symptoms

Calcium Deficiency

SP6 (Sanyinjiao) - Spleen 6

What kind of approach would I actually stick with?

Hands-on relief — acupressure I can do myself or acupuncture from a pro

LV3 (Taichong)

SP6 (Sanyinjiao) - Spleen 6

Herbal remedies with a long track record — I like plant-based options

A simple daily supplement I can take with breakfast and forget about

Getting to the root cause — check whether a nutrient gap is fueling my symptoms

Calcium Deficiency

Magnesium Deficiency

Vitamin B6 (Pyridoxine) Deficiency

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