Conditions in this group
Best-supported options
Ranked by the strength of human research, strongest first. A grade describes the evidence, not how well something will work for you.
- ExerciseAStrong evidenceUsed to improve heart health, mental health, weight management, blood sugar control, strength, and longevity.
- CurcuminAStrong evidenceBest known for calming inflammation, easing joint pain, supporting brain health, and helping the body manage oxidative stress.Safety: caution — read the full safety section before use
- Vitamin DAStrong evidenceSupports bone strength, immune defense, mood, muscle function, and may reduce the risk of several chronic diseases.Safety: caution — read the full safety section before use
- Boswellia SerrataAStrong evidenceBest known for easing joint pain and stiffness, especially in osteoarthritis and inflammatory conditions of the gut and airways.Safety: caution — read the full safety section before use
- MagnesiumAStrong evidenceMost people turn to magnesium for better sleep, less anxiety, fewer muscle cramps, and relief from migraines or PMS.Safety: caution — read the full safety section before use
- BerberineAStrong evidenceBest known for lowering blood sugar, improving insulin sensitivity, and supporting healthy cholesterol and weight.Safety: caution — read the full safety section before use
- Capsaicin (topical)AStrong evidenceRelieves chronic nerve pain, joint pain from arthritis, and muscle soreness when applied directly to the skin.Safety: caution — read the full safety section before use
- Alpha Lipoic AcidAStrong evidenceBest known for easing diabetic nerve pain, improving insulin sensitivity, and providing broad antioxidant protection throughout the body.Safety: caution — read the full safety section before use
Traditional use in this group
Used in a healing tradition for this group of conditions. These carry no evidence grade — they have not been shown to work in human trials, and are listed because people look for them, not as a recommendation.
Pressure points used for these conditions
Acupressure points traditionally used for the conditions in this group. Each point page sets out what the evidence for it does and does not show.
- LI4 (Hegu) - Large Intestine 4Located on the back of the hand between the thumb and index finger, this point is part of the Large Intestine meridian, which is associated with releasing tension and balancing bodily functions.
- PC6 (Neiguan) - Pericardium 6Located on the inner forearm, about three finger-widths above the wrist crease, between the tendons, PC6 is widely known for its ability to alleviate nausea, calm the mind, and reduce stress.
- HT7 (Shenmen) - Heart 7It is located on the wrist crease, on the pinky side of the inner forearm.
- GB34 (Yanglingquan) - Gallbladder 34It is located on the outer side of the lower leg, just below the knee.
- ST36 (Zusanli)Located just below the knee, ST36 is frequently used to support digestive health, boost energy, and strengthen immunity.
- BL23 (Shenshu) - Bladder 23 BL23, also known as "Shenshu" or the “Kidney Shu,” is a critical acupuncture and acupressure point located on the Bladder meridian.
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Reviewed by the HealisticMD editorial team How we grade evidence →