Educational information, not medical advice — ask your doctor or midwife.
Contrayerba is the dried root of Dorstenia contrajerva, a small plant in the fig family. It grows in Mexico, Central America and parts of the Caribbean. Folk healers used the root mainly to bring on sweat and to settle the gut.
The Spanish name means "counter-herb". It was once shipped to Europe and sold as a remedy for snakebite, fever and poison. Today it is mostly a regional home remedy and a rare herbal product.
Here is the honest verdict. Human evidence is close to zero, so no health claim for it can be called proven. Long use in tradition is not proof that it works, and it is not proof that it is safe.
One point matters before you read further. The root contains compounds that react with sunlight and can burn skin.
No one has shown how contrayerba acts in the human body.
Lab work points to furanocoumarins as the main active group. These compounds react with ultraviolet light from the sun. In people, that reaction is known to cause redness, burns and blistering.
Extracts of Dorstenia plants slow some bacteria and fungi in test tubes. Whether that does anything in a sick person is not known. No trial has tested it.
Related coumarins can block liver enzymes in lab studies. Those enzymes clear many prescription drugs. This is a reason for care, not a proven drug effect.
The old sweat-promoting claim has never been measured in a modern study. The same is true for the gut and fever uses.
Contrayerba is sold mainly as the dried root, whole or ground to a powder.
You may also meet it as a tincture (an alcohol extract). It sometimes appears as a minor part of mixed herbal formulas.
In Latin American markets it is often sold loose by weight. Species and strength are rarely stated.
Traditional healers made a water infusion or a boiled decoction of the root. Some used the powder in mouth rinses or on the skin.
It is uncommon in mainstream shops in the UK, US and Europe. No standard extract exists, so two products can differ a lot.
Contrayerba has a long record in Latin American folk medicine.
Indigenous and colonial healers in Mexico and Central America gave the root for fevers, loose bowels and dysentery. The name reflects its old reputation against poisons and snakebite.
Spanish traders carried it to Europe in the 1500s and 1600s. It entered the London and other pharmacopoeias as Radix Contrayervae, listed as a sweat-promoting tonic.
It was a well-known pharmacy item for roughly two centuries. European doctors dropped it during the 1800s as other drugs took its place.
The root is still used in regional home remedies and sold in some markets today.
Stop using it and get medical advice if any of these happen.
See a doctor for a rash, blistering or a burn after time in the sun. Also see a doctor for ongoing vomiting, bad stomach pain, or yellowing of the skin or eyes.
Get emergency help for swelling of the face, lips or throat, or for trouble breathing.
Seek urgent care for a fever above 39C, diarrhoea with blood, or a fever that lasts more than three days.
For any snakebite, go straight to hospital. Do not wait to see if a herb helps.
Contrayerba is not approved as a medicine in the UK, the US, Canada or the EU. In the US it may be sold as a dietary supplement, which means it is not checked for safety or effect before sale. It was listed in old European pharmacopoeias, but that status ended in the 1800s.
Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
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