Educational information, not medical advice.See how evidence is graded

Waking up drenched in sweat at night

You wake up wet. The sheets are damp, your top is damp, and your hair may be damp too. Your heart may pound for a minute, and then you feel cold and clammy.

Many women get this in the years before periods stop. That stretch of time is called perimenopause. A hot flash that happens while you sleep is called a night sweat.

A perimenopause night sweat has a pattern. Heat starts in your chest, neck, or face and spreads out. Then it fades and leaves you chilled and damp.

You may also notice your periods coming closer together or further apart. You may get the same heat rush during the day. Those two clues point toward hormones.

But plain heat in the room can do this too, and so can a few health problems. The rest of this page helps you tell them apart.

When to see someone

Go to an emergency room now if you have drenching sweats with chest pain, trouble breathing, confusion, or a stiff neck with a bad headache. Also go if you feel faint and your heart is racing and will not settle.

Call your doctor for a same-week visit if sweats come with a fever, a cough that will not clear, or weight loss you did not plan. Do the same for a new lump, swollen glands in your neck, armpit, or groin, or itchy skin all over.

Book a visit if sweats soak your sheets most nights for more than two or three weeks. Also book if you are under 40 and your periods have changed, since early menopause needs a check.

Call your doctor if the sweats started within weeks of a new medicine or a dose change. Keep taking it until you have spoken to them.

Contact your doctor promptly if you bleed between periods, bleed after sex, have very heavy periods, or bleed at all after your periods had stopped. This needs a look, whatever your age.

If you take insulin or diabetes pills and wake shaky, hungry, or muddled, tell your diabetes team this week. Your doses may need a change.

Ask for a sleep check if your partner hears you snore, gasp, or stop breathing. Untreated sleep apnea raises risk to your heart.

Finally, see someone if the sweats are wrecking your sleep, your mood, or your work. That is a good enough reason on its own.

Why it happens

Estrogen is a hormone your ovaries make. In perimenopause it does not fall in a smooth line. It swings up and down, sometimes week to week.

A small part of your brain called the hypothalamus acts like a thermostat. Those hormone swings make it more touchy. It starts reading a normal body temperature as too hot.

So it does what it would do in a heat wave. It opens the blood vessels near your skin and turns on your sweat glands. That is the flush, the pounding heart, and the wet sheets.

Then the sweat dries and cools you too far, so you shiver. Night is often worse because the room, the blankets, and your body heat stack up. Alcohol, spicy food, and stress make the thermostat even more touchy.

What else it could be

Night sweats have several common causes, and they do not all feel the same. Picking the wrong one means trying the wrong fix. Here is how to tell them apart.

Too much heat: a warm room, a thick duvet, or a partner who runs hot. The sweat is all over, with no heat rush first, and no chill after. It gets better the night you cool the room down.

Alcohol or a big spicy meal late at night. Sweating comes a few hours after, often with a light, broken sleep. It tracks with the nights you drank or ate late.

Anxiety or panic in sleep: you wake with a racing heart, fear, and fast breathing. The sweat feels cold and clammy from the start, not hot. There is no spreading warmth up the chest.

Sleep apnea: you snore, gasp, or stop breathing for moments. Look for a morning headache, a dry mouth, and heavy daytime sleepiness. The sweat is often on the head and neck.

Low blood sugar at night, mostly in people on insulin or diabetes pills. You wake shaky, hungry, and muddled, and eating fixes it fast. This needs a talk with your doctor about your doses.

An overactive thyroid: you sweat in the day as well as at night. Add a fast heart, shaky hands, weight loss without trying, and loose stools. A simple blood test checks this.

Medicines: antidepressants, tamoxifen, steroids, and some pain and diabetes drugs. The clue is timing, since sweats start within weeks of a new drug or a dose change. Do not stop a drug on your own, but do ask about it.

An infection: fever, aches, cough, or feeling sick along with the sweats. This comes on over days, not months.

Rarely, soaking sweats most nights for weeks can be a sign of a blood cancer such as lymphoma. The warning signs are weight loss you did not plan, swollen glands, itchy skin, and fevers. That mix needs a doctor soon, not a home remedy.

How to read the grades below

The options below come from our page on Perimenopause. Each one carries two labels.

The first label is the evidence grade. A means strong trials in people, B means smaller or mixed studies, and C means early or limited findings. D means lab work only, and “insufficient” means the research cannot settle it yet.

The second label is the traditional tier. T3 means long use in more than one tradition, T2 means long use in one, and T1 means known use. T0 means no such record.

These grades come from research on Perimenopause, the parent Health Topic, not on waking up drenched in sweat at night.

A grade tells you how strong the research is, not how well something will work for you. Talk to a doctor or pharmacist before you start anything, above all if you take other medicines.

What to try first

Start with the room, because it is free and it works fast. Aim for a cool bedroom, around 60 to 67 degrees. Run a fan and keep cool water by the bed.

Layers you can kick off, rather than one thick duvet, work well for some people. Pick cotton or wicking sleepwear over silk or fleece. Some people keep a spare top nearby to swap in.

Test your triggers for two weeks. Cut alcohol in the evening, and skip spicy food and big late meals. Keep a short note each night so you can see the pattern.

Try slow paced breathing when you feel a flush start. Breathe in for a count of four and out for a count of six. Keep it up for a few minutes.

If you smoke, quitting tends to ease flushes. Steady sleep and wake times help too. So does regular movement in the day, though not right before bed.

If you want to try a supplement, here is what the evidence says. Soy Isoflavones (evidence grade A, traditional tier T0) has the strongest trial support of the options here for hot flashes and night sweats. Ashwagandha (evidence grade A, traditional tier T3) also holds an A grade and is used for stress and sleep, with a long history in Ayurvedic medicine.

Melatonin (evidence grade A, traditional tier T0) carries an A grade for sleep timing, not for sweating itself. It may help if the real problem is trouble falling back to sleep. It does not cool the flush.

Black Cohosh (Cimicifuga racemosa) (evidence grade B, traditional tier T2) is one of the most studied herbs for menopause symptoms, with mixed results. Red Clover (Trifolium pratense) (evidence grade B, traditional tier T2) and Maca root (evidence grade B, traditional tier T2) also sit at a B grade. B means some supportive trials, not a settled answer.

Shatavari (evidence grade C, traditional tier T3) has weaker trial support and comes mainly from traditional Ayurvedic use. Acupuncture (evidence grade insufficient, traditional tier T3) and Saffron (Crocus sativus) (evidence grade insufficient, traditional tier T3) are both listed as insufficient. That means the research so far is too thin to judge, and their use rests on tradition.

Ask your doctor before you try any of these, above all if you have had breast cancer or a blood clot. Some of these plants act on estrogen pathways in the body. Prescription options also exist, both hormonal and not, so it is fair to ask about those.

How long it takes

Cooling the room and changing bedding can help the same night. Give it three nights before you judge it. Many people find this alone cuts the worst of it.

Trigger changes, like dropping evening alcohol, take about one to two weeks to show up. Keep the note going so you can see real change and not just a good week.

Supplements are slower. Most menopause herbs are studied over 4 to 12 weeks. If nothing has shifted by 12 weeks, it is fair to stop and try another path.

Melatonin works on sleep timing within days, not weeks. Acupuncture courses in studies usually run several weeks of repeat sessions.

The bigger picture: perimenopause night sweats often last a few years, and for some people longer. They usually fade after periods stop. That is an average, not a promise for you, and treatment can make the years easier.

Perimenopause: natural remedies and the evidence behind them

14 options · 4 graded A · 1 graded B · 1 graded C · 8 traditional or ungraded

Which part of perimenopause is hitting me hardest right now?

Hot flashes and night sweats — I'm overheating day and night

  1. Black Cohosh

    Supported by controlled trials· Centuries of traditional use (Evidence grade A · Traditional use long-standing)Long-standing traditional staple

    Meta-analysis supports easing hot flashes

    Why it may be relevant
    If hot flashes and night sweats are your biggest struggle, black cohosh is the botanical most often turned to for these vasomotor symptoms during the menopausal transition.
    Why try it
    Black cohosh is the most widely studied botanical for menopausal hot flashes and night sweats. A 2023 meta-analysis of randomized trials found black cohosh extracts can improve menopausal symptoms, though results vary from product to product and it is not right for everyone.
    Dose or use
    20-40 mg of a standardized root extract once or twice daily; follow product labeling.
    Time to results
    Typically 4-8 weeks
    Key study
    Meta-analysis (2023, PMID 37192826): Black cohosh extracts in women with menopausal symptoms pooled randomized controlled trials and reported improvement in menopausal symptoms with black cohosh extract.
    Caution
    Not for use in pregnancy. Avoid if you have a liver condition, and stop and see a doctor if you notice signs of liver trouble such as dark urine or yellowing skin.
  2. Soy Isoflavones

    Supported by controlled trials· Centuries of traditional use (Evidence grade A · Traditional use long-standing)Long-standing traditional staple

    Meta-analysis in perimenopausal women

    Why it may be relevant
    If hot flashes and night sweats are hitting hardest, soy isoflavones are phytoestrogens that gently mimic estrogen to help ease these vasomotor symptoms.
    Why try it
    Soy isoflavones are plant compounds with mild estrogen-like activity. A 2025 systematic review and meta-analysis in perimenopausal women found they can modestly reduce menopausal symptoms.
    Dose or use
    40-80 mg of soy isoflavones daily, taken with food; follow product labeling.
    Time to results
    Typically 6-12 weeks
    Key study
    Meta-analysis (2025, PMID 40718787): Effects of soy isoflavones on menopausal symptoms in perimenopausal women pooled 12 studies and found soy isoflavones significantly reduced menopausal symptoms (Hedges' g = -0.25).
    Caution
    Check with your doctor before use if you have a history of an estrogen-sensitive breast condition or take thyroid medication.
  3. Red Clover

    Supported by controlled trials· Centuries of traditional use (Evidence grade A · Traditional use long-standing)Long-standing traditional staple

    Meta-analysis supports fewer hot flashes

    Why it may be relevant
    If hot flashes and night sweats are hitting hardest, red clover is an isoflavone-rich herb studied for easing these vasomotor symptoms.
    Why try it
    Red clover is a source of isoflavones with mild estrogen-like activity. A 2021 systematic review and meta-analysis of randomized trials in peri- and postmenopausal women found it can reduce the daily number of hot flushes.
    Dose or use
    40-80 mg of red clover isoflavones daily; follow product labeling.
    Time to results
    Typically 8-12 weeks
    Key study
    Meta-analysis (2021, PMID 33920485): Red clover extract to relieve hot flushes and menopausal symptoms in peri- and postmenopausal women pooled 8 trials and found a significant reduction in daily hot flushes versus placebo.
    Caution
    Check with your doctor before use if you have an estrogen-sensitive condition or take blood thinners.
  4. Acupuncture

    Supported by controlled trials· Centuries of traditional use (Evidence grade A · Traditional use long-standing)Long-standing traditional staple

    Meta-analysis supports easing perimenopausal symptoms

    Why it may be relevant
    If hot flashes and night sweats are your biggest struggle, acupuncture has been studied specifically for perimenopausal symptoms, including vasomotor complaints.
    Why try it
    Acupuncture uses fine needles placed by a licensed practitioner. A 2025 network meta-analysis of randomized trials in perimenopausal women found acupuncture therapies can help reduce symptoms such as hot flashes, insomnia, and mood changes, though how much benefit you get can vary by technique and practitioner.
    Dose or use
    Weekly 20-30 minute sessions with a licensed acupuncturist; a typical course is 6-12 sessions.
    Time to results
    Typically 4–8 weeks of regular sessions
    Key study
    Network meta-analysis (2025, PMID 41626026): Comparative effectiveness of different acupuncture therapies for perimenopausal syndrome pooled 49 randomized controlled trials (4,579 participants) and found acupuncture approaches improved perimenopausal symptoms versus controls.
    Caution
    Seek a licensed acupuncturist; generally well-tolerated.

Broken sleep and low energy — I wake up tired and drag all day

  1. Ashwagandha

    Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple

    Early clinical research in perimenopausal women

    Why it may be relevant
    If low energy and poor sleep are your main struggles, ashwagandha is one of the few options with a clinical trial conducted directly in perimenopausal women.
    Why try it
    A single randomized, double-blind, placebo-controlled trial in perimenopausal women found that ashwagandha root extract may help ease climacteric symptoms, including fatigue and sleep disturbance; larger studies are needed to confirm this.
    Dose or use
    300–600 mg of a standardized root extract daily; follow product labeling.
    Time to results
    Typically 4–8 weeks
    Key study
    One small RCT (2021, PMID 34553463) of an ashwagandha (Withania somnifera) root extract in women during perimenopause reported improvement in climacteric symptoms versus placebo; findings await replication in larger trials.
    Caution
    Avoid in pregnancy; check with your doctor if you take thyroid medications or immunosuppressants.
  2. Melatonin

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Sleep hormone for menopause-related insomnia

    Why it may be relevant
    If poor sleep is dragging your energy down, melatonin is a sleep-timing hormone that some women try for the disrupted sleep that often comes with perimenopause.
    Why try it
    Melatonin is the hormone that signals your body it is time to sleep. It is best supported for helping you fall asleep; trials specifically in menopausal women have not consistently shown better overall sleep quality, so results vary. It remains ungraded here because no on-condition trial is cited for it.
    Dose or use
    0.5-3 mg taken 30-60 minutes before bed; start with the lowest dose.
    Time to results
    Often within a few nights
    Key study
    A 2026 meta-analysis of randomized trials in menopausal women (PMID 41693954) did not find a significant improvement in sleep quality with melatonin, so its use here rests on melatonin's general role in sleep timing rather than proven menopause-specific benefit.
    Caution
    May cause morning grogginess or vivid dreams; avoid before driving. Check with your doctor if you take blood thinners or sedatives.
  3. Maca root

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Adaptogen for energy and menopause support

    Why it may be relevant
    If you want broad support through the transition, maca is an adaptogenic root traditionally used to steady energy, mood, and libido.
    Why try it
    Maca is a Peruvian root used to help the body adapt to stress and support energy and libido during the menopausal transition. Its use here rests on tradition rather than cited clinical trials.
    Dose or use
    1,500-3,000 mg of maca root powder daily; follow product labeling.
    Time to results
    Typically 6-12 weeks
    Key study
    Traditionally used to ease menopause symptoms and support energy and libido; this specific use has not been confirmed in cited controlled clinical trials.
    Caution
    Generally well tolerated. Check with your doctor if you have a thyroid condition, as raw maca contains goitrogens.
  4. Magnesium Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Low magnesium can drive fatigue and poor sleep

    Why it may be relevant
    If you feel run-down and can't sleep well, low magnesium is a common and correctable cause of fatigue, restlessness, and disturbed sleep.
    Why try it
    Magnesium supports muscle relaxation, nerve calm, and sleep. Levels are often low in midlife, and correcting a genuine shortfall can ease fatigue and restlessness.
    Dose or use
    Ask your doctor about checking your levels. Food sources include leafy greens, nuts, seeds, and whole grains.
    Time to results
    Typically 2-6 weeks once corrected
    Key study
    This is a nutritional-deficiency profile rather than a treatment claim; the symptoms listed reflect what a genuine magnesium shortfall can cause.
    Caution
    Too much supplemental magnesium can cause loose stools; check with your doctor first if you have kidney problems.

Mood swings, anxiety, or feeling emotionally on edge

  1. Ashwagandha

    Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple

    Early clinical research in perimenopausal women

    Why it may be relevant
    If low energy and poor sleep are your main struggles, ashwagandha is one of the few options with a clinical trial conducted directly in perimenopausal women.
    Why try it
    A single randomized, double-blind, placebo-controlled trial in perimenopausal women found that ashwagandha root extract may help ease climacteric symptoms, including fatigue and sleep disturbance; larger studies are needed to confirm this.
    Dose or use
    300–600 mg of a standardized root extract daily; follow product labeling.
    Time to results
    Typically 4–8 weeks
    Key study
    One small RCT (2021, PMID 34553463) of an ashwagandha (Withania somnifera) root extract in women during perimenopause reported improvement in climacteric symptoms versus placebo; findings await replication in larger trials.
    Caution
    Avoid in pregnancy; check with your doctor if you take thyroid medications or immunosuppressants.
  2. Saffron (Crocus sativus)

    Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use recognised)Recognised traditional use

    Early trial for mood in menopausal women

    Why it may be relevant
    If mood swings and emotional sensitivity are your primary concern, saffron has early clinical research for supporting mood during the menopausal years.
    Why try it
    Saffron is a spice studied for mood support. A small randomized trial in postmenopausal women found saffron improved happiness scores; evidence specific to perimenopause is still limited, so this is early rather than definitive.
    Dose or use
    Follow product labeling; consult a healthcare practitioner.
    Time to results
    Typically 4–8 weeks
    Key study
    Randomized controlled trial (2023, PMID 37264347): The effect of saffron herbal tea on happiness in postmenopausal women enrolled 72 women and found saffron improved happiness questionnaire scores versus control. It was small and conducted in postmenopausal (not perimenopausal) women, so the evidence is preliminary.
    Caution
    High doses should be avoided in pregnancy; may interact with antidepressants — check with your doctor.
  3. Vitamin D Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Low vitamin D affects bone, mood, and energy

    Why it may be relevant
    If you want broad support, vitamin D is worth checking. A shortfall is common in midlife and affects bone strength, mood, and energy as estrogen declines.
    Why try it
    Vitamin D supports bone health, mood, and energy, all under extra strain during the menopausal transition. Correcting a confirmed shortfall is a simple, high-value step.
    Dose or use
    Ask your doctor for a blood test. Sunlight and foods like fatty fish and fortified dairy help, and supplements can correct a shortfall.
    Time to results
    Typically 4-12 weeks once corrected
    Key study
    This is a nutritional-deficiency profile rather than a treatment claim; the effects listed reflect what a genuine vitamin D shortfall can cause during the menopausal transition.
    Caution
    Very high supplemental doses can be harmful; dose to your blood level with your doctor's guidance.
  4. HT7 (Shenmen) - Heart 7

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Calming acupressure point for mood and anxiety

    Why it may be relevant
    If mood swings and anxiety are your main concern, HT7 is the classic calming point used to settle the mind and ease worry.
    Why try it
    HT7, the 'Spirit Gate,' is used in traditional Chinese medicine to calm anxiety and quiet the mind. It is a simple self-acupressure practice based on tradition.
    Dose or use
    Press the point on the inner wrist crease, on the pinky side, for 1-2 minutes on each wrist whenever you feel tense.
    Time to results
    May feel calming right away
    Key study
    Used in traditional Chinese medicine to calm anxiety and support sleep; this specific use has not been confirmed in cited controlled clinical trials.
    Caution
    Use gentle pressure only. This supports relaxation and is not a treatment for a diagnosed anxiety disorder.

It's a bit of everything — I want overall hormonal balance through the transition

  1. Maca root

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Adaptogen for energy and menopause support

    Why it may be relevant
    If you want broad support through the transition, maca is an adaptogenic root traditionally used to steady energy, mood, and libido.
    Why try it
    Maca is a Peruvian root used to help the body adapt to stress and support energy and libido during the menopausal transition. Its use here rests on tradition rather than cited clinical trials.
    Dose or use
    1,500-3,000 mg of maca root powder daily; follow product labeling.
    Time to results
    Typically 6-12 weeks
    Key study
    Traditionally used to ease menopause symptoms and support energy and libido; this specific use has not been confirmed in cited controlled clinical trials.
    Caution
    Generally well tolerated. Check with your doctor if you have a thyroid condition, as raw maca contains goitrogens.
  2. Vitamin D Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Low vitamin D affects bone, mood, and energy

    Why it may be relevant
    If you want broad support, vitamin D is worth checking. A shortfall is common in midlife and affects bone strength, mood, and energy as estrogen declines.
    Why try it
    Vitamin D supports bone health, mood, and energy, all under extra strain during the menopausal transition. Correcting a confirmed shortfall is a simple, high-value step.
    Dose or use
    Ask your doctor for a blood test. Sunlight and foods like fatty fish and fortified dairy help, and supplements can correct a shortfall.
    Time to results
    Typically 4-12 weeks once corrected
    Key study
    This is a nutritional-deficiency profile rather than a treatment claim; the effects listed reflect what a genuine vitamin D shortfall can cause during the menopausal transition.
    Caution
    Very high supplemental doses can be harmful; dose to your blood level with your doctor's guidance.
  3. CV4 (Guanyuan) - Conception Vessel 4

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    TCM point for reproductive and hormonal support

    Why it may be relevant
    For overall hormonal support, CV4 is a core traditional point used to support reproductive and menstrual health.
    Why try it
    Known as the 'Gate of Origin,' CV4 is used in traditional Chinese medicine to support ovarian and uterine function and help regulate cycles. It is a tradition-based self-care point.
    Dose or use
    Press about three finger-widths below the navel with gentle, steady pressure for 1-2 minutes daily.
    Time to results
    Varies; use regularly
    Key study
    Used in traditional Chinese medicine for reproductive and hormonal support; this specific use has not been confirmed in cited controlled clinical trials.
    Caution
    Avoid strong stimulation during pregnancy or on a full bladder; use gentle pressure only.
  4. SP6 (Sanyinjiao) - Spleen 6

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Classic women's-health acupressure point

    Why it may be relevant
    If you are after overall balance, SP6 is the traditional go-to acupressure point for women's hormonal and menstrual health.
    Why try it
    SP6 sits where three meridians meet and is used in traditional Chinese medicine to support hormonal balance and ease menstrual and menopausal symptoms. It is a self-care practice based on tradition.
    Dose or use
    Press the point, about a hand-width above the inner ankle bone, firmly for 1-2 minutes on each leg, daily.
    Time to results
    Varies; use regularly
    Key study
    Used in traditional Chinese medicine for women's hormonal and menstrual health; this specific use has not been confirmed in cited controlled clinical trials.
    Caution
    Do not stimulate SP6 during pregnancy, as it is traditionally avoided. Use steady pressure to avoid bruising.
  5. Shatavari

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use

    Traditionally supports female hormonal harmony

    Why it may be relevant
    Shatavari is a go-to traditional herb for women seeking broad hormonal and reproductive system support throughout transitional life stages.
    Why try it
    Traditionally used in Ayurvedic medicine to nourish and tonify the female reproductive system and support hormonal equilibrium.
    Dose or use
    Follow product labeling; consult a healthcare practitioner.
    Time to results
    Typically 6–12 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Avoid if you have estrogen-sensitive conditions; consult your doctor before use.

What kind of support fits me best right now?

Hands-on care — acupuncture sessions or acupressure points I can press myself

  1. Acupuncture

    Supported by controlled trials· Centuries of traditional use (Evidence grade A · Traditional use long-standing)Long-standing traditional staple

    Meta-analysis supports easing perimenopausal symptoms

    Why it may be relevant
    If hot flashes and night sweats are your biggest struggle, acupuncture has been studied specifically for perimenopausal symptoms, including vasomotor complaints.
    Why try it
    Acupuncture uses fine needles placed by a licensed practitioner. A 2025 network meta-analysis of randomized trials in perimenopausal women found acupuncture therapies can help reduce symptoms such as hot flashes, insomnia, and mood changes, though how much benefit you get can vary by technique and practitioner.
    Dose or use
    Weekly 20-30 minute sessions with a licensed acupuncturist; a typical course is 6-12 sessions.
    Time to results
    Typically 4–8 weeks of regular sessions
    Key study
    Network meta-analysis (2025, PMID 41626026): Comparative effectiveness of different acupuncture therapies for perimenopausal syndrome pooled 49 randomized controlled trials (4,579 participants) and found acupuncture approaches improved perimenopausal symptoms versus controls.
    Caution
    Seek a licensed acupuncturist; generally well-tolerated.
  2. CV4 (Guanyuan) - Conception Vessel 4

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    TCM point for reproductive and hormonal support

    Why it may be relevant
    For overall hormonal support, CV4 is a core traditional point used to support reproductive and menstrual health.
    Why try it
    Known as the 'Gate of Origin,' CV4 is used in traditional Chinese medicine to support ovarian and uterine function and help regulate cycles. It is a tradition-based self-care point.
    Dose or use
    Press about three finger-widths below the navel with gentle, steady pressure for 1-2 minutes daily.
    Time to results
    Varies; use regularly
    Key study
    Used in traditional Chinese medicine for reproductive and hormonal support; this specific use has not been confirmed in cited controlled clinical trials.
    Caution
    Avoid strong stimulation during pregnancy or on a full bladder; use gentle pressure only.
  3. HT7 (Shenmen) - Heart 7

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Calming acupressure point for mood and anxiety

    Why it may be relevant
    If mood swings and anxiety are your main concern, HT7 is the classic calming point used to settle the mind and ease worry.
    Why try it
    HT7, the 'Spirit Gate,' is used in traditional Chinese medicine to calm anxiety and quiet the mind. It is a simple self-acupressure practice based on tradition.
    Dose or use
    Press the point on the inner wrist crease, on the pinky side, for 1-2 minutes on each wrist whenever you feel tense.
    Time to results
    May feel calming right away
    Key study
    Used in traditional Chinese medicine to calm anxiety and support sleep; this specific use has not been confirmed in cited controlled clinical trials.
    Caution
    Use gentle pressure only. This supports relaxation and is not a treatment for a diagnosed anxiety disorder.
  4. SP6 (Sanyinjiao) - Spleen 6

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Classic women's-health acupressure point

    Why it may be relevant
    If you are after overall balance, SP6 is the traditional go-to acupressure point for women's hormonal and menstrual health.
    Why try it
    SP6 sits where three meridians meet and is used in traditional Chinese medicine to support hormonal balance and ease menstrual and menopausal symptoms. It is a self-care practice based on tradition.
    Dose or use
    Press the point, about a hand-width above the inner ankle bone, firmly for 1-2 minutes on each leg, daily.
    Time to results
    Varies; use regularly
    Key study
    Used in traditional Chinese medicine for women's hormonal and menstrual health; this specific use has not been confirmed in cited controlled clinical trials.
    Caution
    Do not stimulate SP6 during pregnancy, as it is traditionally avoided. Use steady pressure to avoid bruising.

Supplements with clinical research behind them — I want studied options first

  1. Black Cohosh

    Supported by controlled trials· Centuries of traditional use (Evidence grade A · Traditional use long-standing)Long-standing traditional staple

    Meta-analysis supports easing hot flashes

    Why it may be relevant
    If hot flashes and night sweats are your biggest struggle, black cohosh is the botanical most often turned to for these vasomotor symptoms during the menopausal transition.
    Why try it
    Black cohosh is the most widely studied botanical for menopausal hot flashes and night sweats. A 2023 meta-analysis of randomized trials found black cohosh extracts can improve menopausal symptoms, though results vary from product to product and it is not right for everyone.
    Dose or use
    20-40 mg of a standardized root extract once or twice daily; follow product labeling.
    Time to results
    Typically 4-8 weeks
    Key study
    Meta-analysis (2023, PMID 37192826): Black cohosh extracts in women with menopausal symptoms pooled randomized controlled trials and reported improvement in menopausal symptoms with black cohosh extract.
    Caution
    Not for use in pregnancy. Avoid if you have a liver condition, and stop and see a doctor if you notice signs of liver trouble such as dark urine or yellowing skin.
  2. Soy Isoflavones

    Supported by controlled trials· Centuries of traditional use (Evidence grade A · Traditional use long-standing)Long-standing traditional staple

    Meta-analysis in perimenopausal women

    Why it may be relevant
    If hot flashes and night sweats are hitting hardest, soy isoflavones are phytoestrogens that gently mimic estrogen to help ease these vasomotor symptoms.
    Why try it
    Soy isoflavones are plant compounds with mild estrogen-like activity. A 2025 systematic review and meta-analysis in perimenopausal women found they can modestly reduce menopausal symptoms.
    Dose or use
    40-80 mg of soy isoflavones daily, taken with food; follow product labeling.
    Time to results
    Typically 6-12 weeks
    Key study
    Meta-analysis (2025, PMID 40718787): Effects of soy isoflavones on menopausal symptoms in perimenopausal women pooled 12 studies and found soy isoflavones significantly reduced menopausal symptoms (Hedges' g = -0.25).
    Caution
    Check with your doctor before use if you have a history of an estrogen-sensitive breast condition or take thyroid medication.
  3. Red Clover

    Supported by controlled trials· Centuries of traditional use (Evidence grade A · Traditional use long-standing)Long-standing traditional staple

    Meta-analysis supports fewer hot flashes

    Why it may be relevant
    If hot flashes and night sweats are hitting hardest, red clover is an isoflavone-rich herb studied for easing these vasomotor symptoms.
    Why try it
    Red clover is a source of isoflavones with mild estrogen-like activity. A 2021 systematic review and meta-analysis of randomized trials in peri- and postmenopausal women found it can reduce the daily number of hot flushes.
    Dose or use
    40-80 mg of red clover isoflavones daily; follow product labeling.
    Time to results
    Typically 8-12 weeks
    Key study
    Meta-analysis (2021, PMID 33920485): Red clover extract to relieve hot flushes and menopausal symptoms in peri- and postmenopausal women pooled 8 trials and found a significant reduction in daily hot flushes versus placebo.
    Caution
    Check with your doctor before use if you have an estrogen-sensitive condition or take blood thinners.
  4. Ashwagandha

    Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple

    Early clinical research in perimenopausal women

    Why it may be relevant
    If low energy and poor sleep are your main struggles, ashwagandha is one of the few options with a clinical trial conducted directly in perimenopausal women.
    Why try it
    A single randomized, double-blind, placebo-controlled trial in perimenopausal women found that ashwagandha root extract may help ease climacteric symptoms, including fatigue and sleep disturbance; larger studies are needed to confirm this.
    Dose or use
    300–600 mg of a standardized root extract daily; follow product labeling.
    Time to results
    Typically 4–8 weeks
    Key study
    One small RCT (2021, PMID 34553463) of an ashwagandha (Withania somnifera) root extract in women during perimenopause reported improvement in climacteric symptoms versus placebo; findings await replication in larger trials.
    Caution
    Avoid in pregnancy; check with your doctor if you take thyroid medications or immunosuppressants.
  5. Saffron (Crocus sativus)

    Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use recognised)Recognised traditional use

    Early trial for mood in menopausal women

    Why it may be relevant
    If mood swings and emotional sensitivity are your primary concern, saffron has early clinical research for supporting mood during the menopausal years.
    Why try it
    Saffron is a spice studied for mood support. A small randomized trial in postmenopausal women found saffron improved happiness scores; evidence specific to perimenopause is still limited, so this is early rather than definitive.
    Dose or use
    Follow product labeling; consult a healthcare practitioner.
    Time to results
    Typically 4–8 weeks
    Key study
    Randomized controlled trial (2023, PMID 37264347): The effect of saffron herbal tea on happiness in postmenopausal women enrolled 72 women and found saffron improved happiness questionnaire scores versus control. It was small and conducted in postmenopausal (not perimenopausal) women, so the evidence is preliminary.
    Caution
    High doses should be avoided in pregnancy; may interact with antidepressants — check with your doctor.
  6. Melatonin

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Sleep hormone for menopause-related insomnia

    Why it may be relevant
    If poor sleep is dragging your energy down, melatonin is a sleep-timing hormone that some women try for the disrupted sleep that often comes with perimenopause.
    Why try it
    Melatonin is the hormone that signals your body it is time to sleep. It is best supported for helping you fall asleep; trials specifically in menopausal women have not consistently shown better overall sleep quality, so results vary. It remains ungraded here because no on-condition trial is cited for it.
    Dose or use
    0.5-3 mg taken 30-60 minutes before bed; start with the lowest dose.
    Time to results
    Often within a few nights
    Key study
    A 2026 meta-analysis of randomized trials in menopausal women (PMID 41693954) did not find a significant improvement in sleep quality with melatonin, so its use here rests on melatonin's general role in sleep timing rather than proven menopause-specific benefit.
    Caution
    May cause morning grogginess or vivid dreams; avoid before driving. Check with your doctor if you take blood thinners or sedatives.

Time-tested herbal tonics from Ayurvedic and traditional medicine

  1. Saffron (Crocus sativus)

    Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use recognised)Recognised traditional use

    Early trial for mood in menopausal women

    Why it may be relevant
    If mood swings and emotional sensitivity are your primary concern, saffron has early clinical research for supporting mood during the menopausal years.
    Why try it
    Saffron is a spice studied for mood support. A small randomized trial in postmenopausal women found saffron improved happiness scores; evidence specific to perimenopause is still limited, so this is early rather than definitive.
    Dose or use
    Follow product labeling; consult a healthcare practitioner.
    Time to results
    Typically 4–8 weeks
    Key study
    Randomized controlled trial (2023, PMID 37264347): The effect of saffron herbal tea on happiness in postmenopausal women enrolled 72 women and found saffron improved happiness questionnaire scores versus control. It was small and conducted in postmenopausal (not perimenopausal) women, so the evidence is preliminary.
    Caution
    High doses should be avoided in pregnancy; may interact with antidepressants — check with your doctor.
  2. Maca root

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Adaptogen for energy and menopause support

    Why it may be relevant
    If you want broad support through the transition, maca is an adaptogenic root traditionally used to steady energy, mood, and libido.
    Why try it
    Maca is a Peruvian root used to help the body adapt to stress and support energy and libido during the menopausal transition. Its use here rests on tradition rather than cited clinical trials.
    Dose or use
    1,500-3,000 mg of maca root powder daily; follow product labeling.
    Time to results
    Typically 6-12 weeks
    Key study
    Traditionally used to ease menopause symptoms and support energy and libido; this specific use has not been confirmed in cited controlled clinical trials.
    Caution
    Generally well tolerated. Check with your doctor if you have a thyroid condition, as raw maca contains goitrogens.
  3. Shatavari

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use

    Traditionally supports female hormonal harmony

    Why it may be relevant
    Shatavari is a go-to traditional herb for women seeking broad hormonal and reproductive system support throughout transitional life stages.
    Why try it
    Traditionally used in Ayurvedic medicine to nourish and tonify the female reproductive system and support hormonal equilibrium.
    Dose or use
    Follow product labeling; consult a healthcare practitioner.
    Time to results
    Typically 6–12 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Avoid if you have estrogen-sensitive conditions; consult your doctor before use.

Root-cause first — check whether a nutrient shortfall is making things worse

  1. Vitamin D Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Low vitamin D affects bone, mood, and energy

    Why it may be relevant
    If you want broad support, vitamin D is worth checking. A shortfall is common in midlife and affects bone strength, mood, and energy as estrogen declines.
    Why try it
    Vitamin D supports bone health, mood, and energy, all under extra strain during the menopausal transition. Correcting a confirmed shortfall is a simple, high-value step.
    Dose or use
    Ask your doctor for a blood test. Sunlight and foods like fatty fish and fortified dairy help, and supplements can correct a shortfall.
    Time to results
    Typically 4-12 weeks once corrected
    Key study
    This is a nutritional-deficiency profile rather than a treatment claim; the effects listed reflect what a genuine vitamin D shortfall can cause during the menopausal transition.
    Caution
    Very high supplemental doses can be harmful; dose to your blood level with your doctor's guidance.
  2. Magnesium Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Low magnesium can drive fatigue and poor sleep

    Why it may be relevant
    If you feel run-down and can't sleep well, low magnesium is a common and correctable cause of fatigue, restlessness, and disturbed sleep.
    Why try it
    Magnesium supports muscle relaxation, nerve calm, and sleep. Levels are often low in midlife, and correcting a genuine shortfall can ease fatigue and restlessness.
    Dose or use
    Ask your doctor about checking your levels. Food sources include leafy greens, nuts, seeds, and whole grains.
    Time to results
    Typically 2-6 weeks once corrected
    Key study
    This is a nutritional-deficiency profile rather than a treatment claim; the symptoms listed reflect what a genuine magnesium shortfall can cause.
    Caution
    Too much supplemental magnesium can cause loose stools; check with your doctor first if you have kidney problems.

Evidence grades describe the strength of published research for Perimenopause, not a promise of results. Nothing here is medical advice — talk to your clinician before starting anything, especially alongside prescription medication.

Questions people ask

Is waking up drenched in sweat always menopause?

No. A hot room, heavy bedding, alcohol, anxiety, sleep apnea, thyroid problems, some medicines, and infections can all do it.

The perimenopause pattern is a rush of heat in the chest, neck, or face, then sweat, then a chill. If there is no heat rush, or if you also sweat in the day, look at the other causes and talk to your doctor.

How do I tell a night sweat from just being too hot in bed?

Being too hot gives you an even, all-over dampness with no heat rush and no chill after. A hormone night sweat starts with a wave of heat that spreads up, then leaves you cold and clammy.

The easiest test is to cool the room to about 60 to 67 degrees, swap the thick duvet for layers, and run a fan for three nights. If the sweats stop, heat was the cause.

Which of these options has the strongest research behind it?

Three options carry an A grade: soy isoflavones (evidence grade A, traditional tier T0), ashwagandha (evidence grade A, traditional tier T3), and melatonin (evidence grade A, traditional tier T0).

Melatonin's A grade is for sleep, not for the sweating itself. An A grade means good studies exist. It does not mean the remedy will work for you.

Check with your doctor first. These can interact with other medicines.

Is black cohosh safe to take?

Black cohosh (Cimicifuga racemosa) has an evidence grade of B and a traditional tier of T2. Many people use it, and it has been studied a fair amount, but the results are mixed. There are rare reports of liver problems, so it is not a good fit if you have liver disease.

Stop taking it and call your doctor if your skin or eyes turn yellow, your urine turns dark, or you have pain in your upper right belly.

Ask your doctor before you start, above all if you take other medicines.

Can I take these if I have had breast cancer?

Talk to your cancer team before you take anything on this list. Some plants, including soy isoflavones and red clover, act on estrogen pathways in the body.

Your team can tell you what fits your case and your other drugs. Night sweats are also a known side effect of tamoxifen, so timing matters as a clue.

How long do perimenopause night sweats last?

For many people they run for a few years, and they often fade after periods stop. Some people have them longer, and some barely notice them.

That is an average across many women, not a set schedule for you. Treatment, both home steps and prescription options, can make those years easier.

When are night sweats a sign of something serious?

The worrying pattern is soaking sweats most nights for weeks, along with weight loss you did not plan, fevers, swollen glands, or itchy skin.

That mix can point to an infection or, more rarely, a blood cancer such as lymphoma. See a doctor within the week if that describes you. Go to an emergency room for sweats with chest pain, trouble breathing, or confusion.

Will cutting out alcohol really help?

It often does, because alcohol widens blood vessels near the skin and disturbs the second half of the night. Many people find evening drinks bring on the worst sweats a few hours later.

Try two weeks with no alcohol after dinner and keep a short nightly note. If the sweats ease, you have found a trigger you control.

Other ways people describe this

Same underlying problem, different words.

These suggestions come from our full page on Perimenopause, where you can see every option and how it is graded. Evidence grades are explained in our methodology, and every phrasing we cover is listed under health topics.

Remedies people try for this

Remedies recommended for the same conditions. Evidence grades are shown on each page.

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Reviewed by the HealisticMD editorial team How we grade evidence →