Psoriasis: What's your main focus for your psoriasis right now?

Commonly suggested options include omega-3 fatty acids, curcumin, probiotics (Lactobacillus plantarum P8), vitamin D Deficiency, nicotinamide riboside and aloe Vera Topical.

Psoriasis: What kind of help feels like the best fit for you?

Commonly suggested options include mediterranean Diet, vitamin D Deficiency, omega-3 fatty acids, curcumin, probiotics (Lactobacillus plantarum P8) and aloe Vera Topical.

Psoriasis: natural remedies and the evidence behind them

10 natural approaches to Psoriasis, graded by evidence — including Aloe Vera Topical, Curcumin and Mediterranean Diet.

10 options · 4 graded B · 2 graded C · 4 traditional or ungraded

What's your main focus for your psoriasis right now?

I want to calm the inflammation driving it from the inside out

Omega-3 fatty acids
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Calms skin inflammation during flares
Why this matches
During an active flare, omega-3s' anti-inflammatory action is most immediately relevant to reducing redness and scaling.
Why try it
Supported by a systematic review, omega-3 fatty acids help modulate the inflammatory pathways that drive psoriatic skin changes.
Dose or use
1,000–3,000 mg EPA+DHA daily with food
Time to results
Typically 4–12 weeks
Key study
Systematic review (2026, PMID 41534196): Therapeutic approach with fatty acids in psoriasis: A systematic review.
Caution
May thin blood at high doses; check with a doctor if on blood thinners or before surgery.
Curcumin
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
RCT-supported oral curcumin as an add-on for plaque psoriasis
Why this matches
For those exploring natural remedies, curcumin from turmeric has both a long traditional history for inflammatory skin concerns and randomized-trial support as an add-on for plaque psoriasis.
Why try it
In a randomized, double-blind, placebo-controlled trial, adding a well-absorbed oral curcumin to standard topical care led to greater improvement in psoriasis severity than topical care alone. It works through anti-inflammatory pathways and is best used as a complement to, not a replacement for, your usual treatment.
Dose or use
Trials used a bioavailable (lecithin-formulated) oral curcumin at about 2 g daily with food. Follow product labeling and consult a healthcare practitioner.
Time to results
Typically 8–12 weeks
Key study
Randomized Controlled Trial (2015, PMID 26090395): a double-blind, placebo-controlled trial in mild-to-moderate psoriasis vulgaris found that adding bioavailable oral curcumin (2 g/day) to topical steroids improved psoriasis severity (PASI) more than topical steroids alone over 12 weeks.
Caution
May interact with blood thinners; avoid high doses in pregnancy or with gallbladder issues.
Probiotics (Lactobacillus plantarum P8)
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Gut-immune support; strain data limited
Why this matches
Targeting internal inflammation makes gut-microbiome support relevant, since the gut-skin immune connection plays a role in psoriasis.
Why try it
A systematic review and meta-analysis found probiotics as a class may reduce psoriasis severity via the gut-immune (gut-skin) axis. P8 is one immune-modulating strain within that class, not the specific strain trialed for psoriasis.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Systematic review & meta-analysis (2024, PMID 38551321): probiotic supplementation may reduce psoriasis severity. Evidence is for probiotics as a category; strain-specific human data for P8 in psoriasis is limited.
Caution
Generally well tolerated; consult a doctor if immunocompromised.
Vitamin D Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low vitamin D is linked to psoriasis severity
Why this matches
To calm inflammation from the inside, it's worth checking vitamin D — low levels are strongly linked to psoriasis and how severe it gets.
Why try it
Vitamin D helps regulate skin-cell growth and immune activity, and deficiency is common in psoriasis. Testing and correcting a confirmed deficiency is a sensible internal step.
Dose or use
Ask your provider for a blood test (25-OH vitamin D) and correct any deficiency under their guidance.
Time to results
Weeks to months to restore healthy levels.
Key study
Vitamin D deficiency is commonly associated with psoriasis and its severity, and vitamin D pathways influence skin-cell growth. This is an observational association, not proof that supplements treat psoriasis.
Caution
Don't megadose vitamin D on your own; too much can be harmful. Correct a deficiency with provider guidance.
Nicotinamide riboside
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)
Emerging NAD+ research; not yet proven
Why this matches
For those focused on internal inflammation, nicotinamide riboside is being explored for the Th17 immune pathway involved in psoriasis, though the evidence is still early.
Why try it
Early, mechanistic research suggests boosting NAD+ may influence the Th17 inflammatory pathway relevant to psoriasis. Human efficacy for psoriasis is not established, so treat this as experimental.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–12 weeks
Key study
Early, mechanistic research only: NAD+ augmentation may affect Th17 (SLIT2/ROBO1) inflammatory signaling relevant to psoriasis. Not yet confirmed in human clinical trials for psoriasis.
Caution
Research is still emerging; discuss with a healthcare provider before use.

I'd like to explore natural and traditional remedies alongside my routine

Aloe Vera Topical
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
Soothing topical gel with RCT support for plaque psoriasis
Why this matches
During a flare, aloe vera gel is a gentle topical you can apply to red, scaly patches — and unlike many soothing gels, it has randomized-trial support in mild-to-moderate plaque psoriasis.
Why try it
In a randomized, double-blind trial in mild-to-moderate plaque psoriasis, topical aloe vera cream reduced skin severity at least as much as a topical steroid over 8 weeks. It is a low-risk, soothing option for calming psoriatic patches.
Dose or use
Apply pure aloe vera gel to affected skin 1-3 times daily.
Time to results
Soothing relief is often quick; measurable improvement over about 8 weeks.
Key study
Randomized Controlled Trial (2010, PMID 19686327): in 80 patients with mild-to-moderate plaque psoriasis, topical aloe vera cream reduced psoriasis severity (PASI) at least as effectively as 0.1% triamcinolone (a topical steroid) over 8 weeks.
Caution
Use plain aloe without added fragrance or alcohol, and patch-test first, as some people react to aloe.
Curcumin
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
RCT-supported oral curcumin as an add-on for plaque psoriasis
Why this matches
For those exploring natural remedies, curcumin from turmeric has both a long traditional history for inflammatory skin concerns and randomized-trial support as an add-on for plaque psoriasis.
Why try it
In a randomized, double-blind, placebo-controlled trial, adding a well-absorbed oral curcumin to standard topical care led to greater improvement in psoriasis severity than topical care alone. It works through anti-inflammatory pathways and is best used as a complement to, not a replacement for, your usual treatment.
Dose or use
Trials used a bioavailable (lecithin-formulated) oral curcumin at about 2 g daily with food. Follow product labeling and consult a healthcare practitioner.
Time to results
Typically 8–12 weeks
Key study
Randomized Controlled Trial (2015, PMID 26090395): a double-blind, placebo-controlled trial in mild-to-moderate psoriasis vulgaris found that adding bioavailable oral curcumin (2 g/day) to topical steroids improved psoriasis severity (PASI) more than topical steroids alone over 12 weeks.
Caution
May interact with blood thinners; avoid high doses in pregnancy or with gallbladder issues.
LI11 (Quchi) - Large Intestine 11
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Acupressure point traditionally used for skin
Why this matches
If you're exploring traditional remedies, LI11 is an acupressure point used in Traditional Chinese Medicine for inflammatory skin conditions.
Why try it
In Traditional Chinese Medicine, LI11 (Quchi) is used to help clear heat and calm inflammatory skin conditions such as psoriasis. This is a traditional practice, not a clinically proven treatment.
Dose or use
Find the point at the outer end of the elbow crease; press firmly for 1-2 minutes on each arm.
Time to results
Varies; used as an ongoing complementary practice.
Key study
Traditionally used in acupressure for inflammatory skin conditions; this use has not been confirmed in controlled clinical trials.
Caution
Acupressure is a complement, not a replacement for medical care; avoid pressing on broken or inflamed skin.
Berberine
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Explored via the gut-inflammation (gut-skin) axis
Why this matches
For a natural-remedy approach, berberine is an exploratory option — used mainly for metabolic and gut health and studied for inflammation via the gut-skin axis rather than as a skin remedy.
Why try it
Berberine has documented anti-inflammatory, antimicrobial, and metabolic actions. Any role in psoriasis is exploratory and works through gut and systemic inflammation, not an established skin-specific tradition.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Used traditionally for metabolic and digestive health; its use for psoriasis is exploratory and has not been confirmed in controlled clinical trials.
Caution
Not recommended during pregnancy; may interact with certain medications — consult a healthcare provider.

I'm building lasting diet and lifestyle habits to keep flares away

Omega-3 fatty acids
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Calms skin inflammation during flares
Why this matches
During an active flare, omega-3s' anti-inflammatory action is most immediately relevant to reducing redness and scaling.
Why try it
Supported by a systematic review, omega-3 fatty acids help modulate the inflammatory pathways that drive psoriatic skin changes.
Dose or use
1,000–3,000 mg EPA+DHA daily with food
Time to results
Typically 4–12 weeks
Key study
Systematic review (2026, PMID 41534196): Therapeutic approach with fatty acids in psoriasis: A systematic review.
Caution
May thin blood at high doses; check with a doctor if on blood thinners or before surgery.
Mediterranean Diet
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Anti-inflammatory eating pattern for long-term control
Why this matches
A lifestyle-focused approach maps directly onto the Mediterranean diet's role as a sustained dietary strategy shown in an RCT to benefit psoriasis patients.
Why try it
The MEDIPSO randomized clinical trial supports this eating pattern — rich in vegetables, olive oil, and fish — for reducing psoriasis severity over time.
Dose or use
Follow a whole-food pattern: emphasize vegetables, legumes, fish, olive oil, and whole grains daily.
Time to results
Typically 8–16 weeks
Key study
RCT (2025, PMID 40991259): Mediterranean Diet and Patients With Psoriasis: The MEDIPSO Randomized Clinical Trial.
Caution
Check with your healthcare provider before starting, especially if you are pregnant or breastfeeding, take prescription medication, or manage a chronic condition.
Vitamin D Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low vitamin D is linked to psoriasis severity
Why this matches
To calm inflammation from the inside, it's worth checking vitamin D — low levels are strongly linked to psoriasis and how severe it gets.
Why try it
Vitamin D helps regulate skin-cell growth and immune activity, and deficiency is common in psoriasis. Testing and correcting a confirmed deficiency is a sensible internal step.
Dose or use
Ask your provider for a blood test (25-OH vitamin D) and correct any deficiency under their guidance.
Time to results
Weeks to months to restore healthy levels.
Key study
Vitamin D deficiency is commonly associated with psoriasis and its severity, and vitamin D pathways influence skin-cell growth. This is an observational association, not proof that supplements treat psoriasis.
Caution
Don't megadose vitamin D on your own; too much can be harmful. Correct a deficiency with provider guidance.

My skin is flaring right now — I want to soothe the red, scaly, itchy patches

Omega-3 fatty acids
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Calms skin inflammation during flares
Why this matches
During an active flare, omega-3s' anti-inflammatory action is most immediately relevant to reducing redness and scaling.
Why try it
Supported by a systematic review, omega-3 fatty acids help modulate the inflammatory pathways that drive psoriatic skin changes.
Dose or use
1,000–3,000 mg EPA+DHA daily with food
Time to results
Typically 4–12 weeks
Key study
Systematic review (2026, PMID 41534196): Therapeutic approach with fatty acids in psoriasis: A systematic review.
Caution
May thin blood at high doses; check with a doctor if on blood thinners or before surgery.
Aloe Vera Topical
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
Soothing topical gel with RCT support for plaque psoriasis
Why this matches
During a flare, aloe vera gel is a gentle topical you can apply to red, scaly patches — and unlike many soothing gels, it has randomized-trial support in mild-to-moderate plaque psoriasis.
Why try it
In a randomized, double-blind trial in mild-to-moderate plaque psoriasis, topical aloe vera cream reduced skin severity at least as much as a topical steroid over 8 weeks. It is a low-risk, soothing option for calming psoriatic patches.
Dose or use
Apply pure aloe vera gel to affected skin 1-3 times daily.
Time to results
Soothing relief is often quick; measurable improvement over about 8 weeks.
Key study
Randomized Controlled Trial (2010, PMID 19686327): in 80 patients with mild-to-moderate plaque psoriasis, topical aloe vera cream reduced psoriasis severity (PASI) at least as effectively as 0.1% triamcinolone (a topical steroid) over 8 weeks.
Caution
Use plain aloe without added fragrance or alcohol, and patch-test first, as some people react to aloe.
Topical Vitamin B12
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Topical cream that soothes flaring, scaly skin
Why this matches
When your skin is actively flaring, a topical you apply directly can calm irritation and slow the fast skin-cell turnover behind scaly patches.
Why try it
Topical vitamin B12 (cobalamin) cream has been studied for psoriasis, where it helped slow excessive skin-cell turnover and soothe irritation.
Dose or use
Apply a thin layer of a cobalamin (B12) cream to affected areas as directed on the product.
Time to results
Often within a few weeks of regular use.
Key study
Clinical study (Clinical Interventions in Aging, 2021): topical vitamin B12 (cobalamin) cream helped slow excessive skin-cell turnover and soothe irritation in psoriasis.
Caution
For external use only; patch-test first if you have sensitive skin, and stop if irritation worsens.

What kind of help feels like the best fit for you?

Diet and nutrition foundations, including checking for deficiencies

Mediterranean Diet
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Anti-inflammatory eating pattern for long-term control
Why this matches
A lifestyle-focused approach maps directly onto the Mediterranean diet's role as a sustained dietary strategy shown in an RCT to benefit psoriasis patients.
Why try it
The MEDIPSO randomized clinical trial supports this eating pattern — rich in vegetables, olive oil, and fish — for reducing psoriasis severity over time.
Dose or use
Follow a whole-food pattern: emphasize vegetables, legumes, fish, olive oil, and whole grains daily.
Time to results
Typically 8–16 weeks
Key study
RCT (2025, PMID 40991259): Mediterranean Diet and Patients With Psoriasis: The MEDIPSO Randomized Clinical Trial.
Caution
Check with your healthcare provider before starting, especially if you are pregnant or breastfeeding, take prescription medication, or manage a chronic condition.
Vitamin D Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low vitamin D is linked to psoriasis severity
Why this matches
To calm inflammation from the inside, it's worth checking vitamin D — low levels are strongly linked to psoriasis and how severe it gets.
Why try it
Vitamin D helps regulate skin-cell growth and immune activity, and deficiency is common in psoriasis. Testing and correcting a confirmed deficiency is a sensible internal step.
Dose or use
Ask your provider for a blood test (25-OH vitamin D) and correct any deficiency under their guidance.
Time to results
Weeks to months to restore healthy levels.
Key study
Vitamin D deficiency is commonly associated with psoriasis and its severity, and vitamin D pathways influence skin-cell growth. This is an observational association, not proof that supplements treat psoriasis.
Caution
Don't megadose vitamin D on your own; too much can be harmful. Correct a deficiency with provider guidance.

Evidence-backed daily supplements I can take by mouth

Omega-3 fatty acids
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Calms skin inflammation during flares
Why this matches
During an active flare, omega-3s' anti-inflammatory action is most immediately relevant to reducing redness and scaling.
Why try it
Supported by a systematic review, omega-3 fatty acids help modulate the inflammatory pathways that drive psoriatic skin changes.
Dose or use
1,000–3,000 mg EPA+DHA daily with food
Time to results
Typically 4–12 weeks
Key study
Systematic review (2026, PMID 41534196): Therapeutic approach with fatty acids in psoriasis: A systematic review.
Caution
May thin blood at high doses; check with a doctor if on blood thinners or before surgery.
Curcumin
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
RCT-supported oral curcumin as an add-on for plaque psoriasis
Why this matches
For those exploring natural remedies, curcumin from turmeric has both a long traditional history for inflammatory skin concerns and randomized-trial support as an add-on for plaque psoriasis.
Why try it
In a randomized, double-blind, placebo-controlled trial, adding a well-absorbed oral curcumin to standard topical care led to greater improvement in psoriasis severity than topical care alone. It works through anti-inflammatory pathways and is best used as a complement to, not a replacement for, your usual treatment.
Dose or use
Trials used a bioavailable (lecithin-formulated) oral curcumin at about 2 g daily with food. Follow product labeling and consult a healthcare practitioner.
Time to results
Typically 8–12 weeks
Key study
Randomized Controlled Trial (2015, PMID 26090395): a double-blind, placebo-controlled trial in mild-to-moderate psoriasis vulgaris found that adding bioavailable oral curcumin (2 g/day) to topical steroids improved psoriasis severity (PASI) more than topical steroids alone over 12 weeks.
Caution
May interact with blood thinners; avoid high doses in pregnancy or with gallbladder issues.
Probiotics (Lactobacillus plantarum P8)
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Gut-immune support; strain data limited
Why this matches
Targeting internal inflammation makes gut-microbiome support relevant, since the gut-skin immune connection plays a role in psoriasis.
Why try it
A systematic review and meta-analysis found probiotics as a class may reduce psoriasis severity via the gut-immune (gut-skin) axis. P8 is one immune-modulating strain within that class, not the specific strain trialed for psoriasis.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Systematic review & meta-analysis (2024, PMID 38551321): probiotic supplementation may reduce psoriasis severity. Evidence is for probiotics as a category; strain-specific human data for P8 in psoriasis is limited.
Caution
Generally well tolerated; consult a doctor if immunocompromised.

Something I apply right to the skin to soothe the patches

Aloe Vera Topical
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
Soothing topical gel with RCT support for plaque psoriasis
Why this matches
During a flare, aloe vera gel is a gentle topical you can apply to red, scaly patches — and unlike many soothing gels, it has randomized-trial support in mild-to-moderate plaque psoriasis.
Why try it
In a randomized, double-blind trial in mild-to-moderate plaque psoriasis, topical aloe vera cream reduced skin severity at least as much as a topical steroid over 8 weeks. It is a low-risk, soothing option for calming psoriatic patches.
Dose or use
Apply pure aloe vera gel to affected skin 1-3 times daily.
Time to results
Soothing relief is often quick; measurable improvement over about 8 weeks.
Key study
Randomized Controlled Trial (2010, PMID 19686327): in 80 patients with mild-to-moderate plaque psoriasis, topical aloe vera cream reduced psoriasis severity (PASI) at least as effectively as 0.1% triamcinolone (a topical steroid) over 8 weeks.
Caution
Use plain aloe without added fragrance or alcohol, and patch-test first, as some people react to aloe.
Topical Vitamin B12
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Topical cream that soothes flaring, scaly skin
Why this matches
When your skin is actively flaring, a topical you apply directly can calm irritation and slow the fast skin-cell turnover behind scaly patches.
Why try it
Topical vitamin B12 (cobalamin) cream has been studied for psoriasis, where it helped slow excessive skin-cell turnover and soothe irritation.
Dose or use
Apply a thin layer of a cobalamin (B12) cream to affected areas as directed on the product.
Time to results
Often within a few weeks of regular use.
Key study
Clinical study (Clinical Interventions in Aging, 2021): topical vitamin B12 (cobalamin) cream helped slow excessive skin-cell turnover and soothe irritation in psoriasis.
Caution
For external use only; patch-test first if you have sensitive skin, and stop if irritation worsens.

Traditional practices and newer, exploratory options I'm curious about

Curcumin
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
RCT-supported oral curcumin as an add-on for plaque psoriasis
Why this matches
For those exploring natural remedies, curcumin from turmeric has both a long traditional history for inflammatory skin concerns and randomized-trial support as an add-on for plaque psoriasis.
Why try it
In a randomized, double-blind, placebo-controlled trial, adding a well-absorbed oral curcumin to standard topical care led to greater improvement in psoriasis severity than topical care alone. It works through anti-inflammatory pathways and is best used as a complement to, not a replacement for, your usual treatment.
Dose or use
Trials used a bioavailable (lecithin-formulated) oral curcumin at about 2 g daily with food. Follow product labeling and consult a healthcare practitioner.
Time to results
Typically 8–12 weeks
Key study
Randomized Controlled Trial (2015, PMID 26090395): a double-blind, placebo-controlled trial in mild-to-moderate psoriasis vulgaris found that adding bioavailable oral curcumin (2 g/day) to topical steroids improved psoriasis severity (PASI) more than topical steroids alone over 12 weeks.
Caution
May interact with blood thinners; avoid high doses in pregnancy or with gallbladder issues.
LI11 (Quchi) - Large Intestine 11
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Acupressure point traditionally used for skin
Why this matches
If you're exploring traditional remedies, LI11 is an acupressure point used in Traditional Chinese Medicine for inflammatory skin conditions.
Why try it
In Traditional Chinese Medicine, LI11 (Quchi) is used to help clear heat and calm inflammatory skin conditions such as psoriasis. This is a traditional practice, not a clinically proven treatment.
Dose or use
Find the point at the outer end of the elbow crease; press firmly for 1-2 minutes on each arm.
Time to results
Varies; used as an ongoing complementary practice.
Key study
Traditionally used in acupressure for inflammatory skin conditions; this use has not been confirmed in controlled clinical trials.
Caution
Acupressure is a complement, not a replacement for medical care; avoid pressing on broken or inflamed skin.
Nicotinamide riboside
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)
Emerging NAD+ research; not yet proven
Why this matches
For those focused on internal inflammation, nicotinamide riboside is being explored for the Th17 immune pathway involved in psoriasis, though the evidence is still early.
Why try it
Early, mechanistic research suggests boosting NAD+ may influence the Th17 inflammatory pathway relevant to psoriasis. Human efficacy for psoriasis is not established, so treat this as experimental.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–12 weeks
Key study
Early, mechanistic research only: NAD+ augmentation may affect Th17 (SLIT2/ROBO1) inflammatory signaling relevant to psoriasis. Not yet confirmed in human clinical trials for psoriasis.
Caution
Research is still emerging; discuss with a healthcare provider before use.
Berberine
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Explored via the gut-inflammation (gut-skin) axis
Why this matches
For a natural-remedy approach, berberine is an exploratory option — used mainly for metabolic and gut health and studied for inflammation via the gut-skin axis rather than as a skin remedy.
Why try it
Berberine has documented anti-inflammatory, antimicrobial, and metabolic actions. Any role in psoriasis is exploratory and works through gut and systemic inflammation, not an established skin-specific tradition.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Used traditionally for metabolic and digestive health; its use for psoriasis is exploratory and has not been confirmed in controlled clinical trials.
Caution
Not recommended during pregnancy; may interact with certain medications — consult a healthcare provider.

Evidence grades describe the strength of published research for Psoriasis, not a promise of results. Nothing here is medical advice — talk to your clinician before starting anything, especially alongside prescription medication.

What's your main focus for your psoriasis right now?

I want to calm the inflammation driving it from the inside out

Omega-3 fatty acids
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Calms skin inflammation during flares
Why this matches
During an active flare, omega-3s' anti-inflammatory action is most immediately relevant to reducing redness and scaling.
Why try it
Supported by a systematic review, omega-3 fatty acids help modulate the inflammatory pathways that drive psoriatic skin changes.
Dose or use
1,000–3,000 mg EPA+DHA daily with food
Time to results
Typically 4–12 weeks
Key study
Systematic review (2026, PMID 41534196): Therapeutic approach with fatty acids in psoriasis: A systematic review.
Caution
May thin blood at high doses; check with a doctor if on blood thinners or before surgery.
Curcumin
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
RCT-supported oral curcumin as an add-on for plaque psoriasis
Why this matches
For those exploring natural remedies, curcumin from turmeric has both a long traditional history for inflammatory skin concerns and randomized-trial support as an add-on for plaque psoriasis.
Why try it
In a randomized, double-blind, placebo-controlled trial, adding a well-absorbed oral curcumin to standard topical care led to greater improvement in psoriasis severity than topical care alone. It works through anti-inflammatory pathways and is best used as a complement to, not a replacement for, your usual treatment.
Dose or use
Trials used a bioavailable (lecithin-formulated) oral curcumin at about 2 g daily with food. Follow product labeling and consult a healthcare practitioner.
Time to results
Typically 8–12 weeks
Key study
Randomized Controlled Trial (2015, PMID 26090395): a double-blind, placebo-controlled trial in mild-to-moderate psoriasis vulgaris found that adding bioavailable oral curcumin (2 g/day) to topical steroids improved psoriasis severity (PASI) more than topical steroids alone over 12 weeks.
Caution
May interact with blood thinners; avoid high doses in pregnancy or with gallbladder issues.
Probiotics (Lactobacillus plantarum P8)
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Gut-immune support; strain data limited
Why this matches
Targeting internal inflammation makes gut-microbiome support relevant, since the gut-skin immune connection plays a role in psoriasis.
Why try it
A systematic review and meta-analysis found probiotics as a class may reduce psoriasis severity via the gut-immune (gut-skin) axis. P8 is one immune-modulating strain within that class, not the specific strain trialed for psoriasis.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Systematic review & meta-analysis (2024, PMID 38551321): probiotic supplementation may reduce psoriasis severity. Evidence is for probiotics as a category; strain-specific human data for P8 in psoriasis is limited.
Caution
Generally well tolerated; consult a doctor if immunocompromised.
Vitamin D Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low vitamin D is linked to psoriasis severity
Why this matches
To calm inflammation from the inside, it's worth checking vitamin D — low levels are strongly linked to psoriasis and how severe it gets.
Why try it
Vitamin D helps regulate skin-cell growth and immune activity, and deficiency is common in psoriasis. Testing and correcting a confirmed deficiency is a sensible internal step.
Dose or use
Ask your provider for a blood test (25-OH vitamin D) and correct any deficiency under their guidance.
Time to results
Weeks to months to restore healthy levels.
Key study
Vitamin D deficiency is commonly associated with psoriasis and its severity, and vitamin D pathways influence skin-cell growth. This is an observational association, not proof that supplements treat psoriasis.
Caution
Don't megadose vitamin D on your own; too much can be harmful. Correct a deficiency with provider guidance.
Nicotinamide riboside
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)
Emerging NAD+ research; not yet proven
Why this matches
For those focused on internal inflammation, nicotinamide riboside is being explored for the Th17 immune pathway involved in psoriasis, though the evidence is still early.
Why try it
Early, mechanistic research suggests boosting NAD+ may influence the Th17 inflammatory pathway relevant to psoriasis. Human efficacy for psoriasis is not established, so treat this as experimental.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–12 weeks
Key study
Early, mechanistic research only: NAD+ augmentation may affect Th17 (SLIT2/ROBO1) inflammatory signaling relevant to psoriasis. Not yet confirmed in human clinical trials for psoriasis.
Caution
Research is still emerging; discuss with a healthcare provider before use.

I'd like to explore natural and traditional remedies alongside my routine

Aloe Vera Topical
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
Soothing topical gel with RCT support for plaque psoriasis
Why this matches
During a flare, aloe vera gel is a gentle topical you can apply to red, scaly patches — and unlike many soothing gels, it has randomized-trial support in mild-to-moderate plaque psoriasis.
Why try it
In a randomized, double-blind trial in mild-to-moderate plaque psoriasis, topical aloe vera cream reduced skin severity at least as much as a topical steroid over 8 weeks. It is a low-risk, soothing option for calming psoriatic patches.
Dose or use
Apply pure aloe vera gel to affected skin 1-3 times daily.
Time to results
Soothing relief is often quick; measurable improvement over about 8 weeks.
Key study
Randomized Controlled Trial (2010, PMID 19686327): in 80 patients with mild-to-moderate plaque psoriasis, topical aloe vera cream reduced psoriasis severity (PASI) at least as effectively as 0.1% triamcinolone (a topical steroid) over 8 weeks.
Caution
Use plain aloe without added fragrance or alcohol, and patch-test first, as some people react to aloe.
Curcumin
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
RCT-supported oral curcumin as an add-on for plaque psoriasis
Why this matches
For those exploring natural remedies, curcumin from turmeric has both a long traditional history for inflammatory skin concerns and randomized-trial support as an add-on for plaque psoriasis.
Why try it
In a randomized, double-blind, placebo-controlled trial, adding a well-absorbed oral curcumin to standard topical care led to greater improvement in psoriasis severity than topical care alone. It works through anti-inflammatory pathways and is best used as a complement to, not a replacement for, your usual treatment.
Dose or use
Trials used a bioavailable (lecithin-formulated) oral curcumin at about 2 g daily with food. Follow product labeling and consult a healthcare practitioner.
Time to results
Typically 8–12 weeks
Key study
Randomized Controlled Trial (2015, PMID 26090395): a double-blind, placebo-controlled trial in mild-to-moderate psoriasis vulgaris found that adding bioavailable oral curcumin (2 g/day) to topical steroids improved psoriasis severity (PASI) more than topical steroids alone over 12 weeks.
Caution
May interact with blood thinners; avoid high doses in pregnancy or with gallbladder issues.
LI11 (Quchi) - Large Intestine 11
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Acupressure point traditionally used for skin
Why this matches
If you're exploring traditional remedies, LI11 is an acupressure point used in Traditional Chinese Medicine for inflammatory skin conditions.
Why try it
In Traditional Chinese Medicine, LI11 (Quchi) is used to help clear heat and calm inflammatory skin conditions such as psoriasis. This is a traditional practice, not a clinically proven treatment.
Dose or use
Find the point at the outer end of the elbow crease; press firmly for 1-2 minutes on each arm.
Time to results
Varies; used as an ongoing complementary practice.
Key study
Traditionally used in acupressure for inflammatory skin conditions; this use has not been confirmed in controlled clinical trials.
Caution
Acupressure is a complement, not a replacement for medical care; avoid pressing on broken or inflamed skin.
Berberine
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Explored via the gut-inflammation (gut-skin) axis
Why this matches
For a natural-remedy approach, berberine is an exploratory option — used mainly for metabolic and gut health and studied for inflammation via the gut-skin axis rather than as a skin remedy.
Why try it
Berberine has documented anti-inflammatory, antimicrobial, and metabolic actions. Any role in psoriasis is exploratory and works through gut and systemic inflammation, not an established skin-specific tradition.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Used traditionally for metabolic and digestive health; its use for psoriasis is exploratory and has not been confirmed in controlled clinical trials.
Caution
Not recommended during pregnancy; may interact with certain medications — consult a healthcare provider.

I'm building lasting diet and lifestyle habits to keep flares away

Omega-3 fatty acids
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Calms skin inflammation during flares
Why this matches
During an active flare, omega-3s' anti-inflammatory action is most immediately relevant to reducing redness and scaling.
Why try it
Supported by a systematic review, omega-3 fatty acids help modulate the inflammatory pathways that drive psoriatic skin changes.
Dose or use
1,000–3,000 mg EPA+DHA daily with food
Time to results
Typically 4–12 weeks
Key study
Systematic review (2026, PMID 41534196): Therapeutic approach with fatty acids in psoriasis: A systematic review.
Caution
May thin blood at high doses; check with a doctor if on blood thinners or before surgery.
Mediterranean Diet
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Anti-inflammatory eating pattern for long-term control
Why this matches
A lifestyle-focused approach maps directly onto the Mediterranean diet's role as a sustained dietary strategy shown in an RCT to benefit psoriasis patients.
Why try it
The MEDIPSO randomized clinical trial supports this eating pattern — rich in vegetables, olive oil, and fish — for reducing psoriasis severity over time.
Dose or use
Follow a whole-food pattern: emphasize vegetables, legumes, fish, olive oil, and whole grains daily.
Time to results
Typically 8–16 weeks
Key study
RCT (2025, PMID 40991259): Mediterranean Diet and Patients With Psoriasis: The MEDIPSO Randomized Clinical Trial.
Caution
Check with your healthcare provider before starting, especially if you are pregnant or breastfeeding, take prescription medication, or manage a chronic condition.
Vitamin D Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low vitamin D is linked to psoriasis severity
Why this matches
To calm inflammation from the inside, it's worth checking vitamin D — low levels are strongly linked to psoriasis and how severe it gets.
Why try it
Vitamin D helps regulate skin-cell growth and immune activity, and deficiency is common in psoriasis. Testing and correcting a confirmed deficiency is a sensible internal step.
Dose or use
Ask your provider for a blood test (25-OH vitamin D) and correct any deficiency under their guidance.
Time to results
Weeks to months to restore healthy levels.
Key study
Vitamin D deficiency is commonly associated with psoriasis and its severity, and vitamin D pathways influence skin-cell growth. This is an observational association, not proof that supplements treat psoriasis.
Caution
Don't megadose vitamin D on your own; too much can be harmful. Correct a deficiency with provider guidance.

My skin is flaring right now — I want to soothe the red, scaly, itchy patches

Omega-3 fatty acids
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Calms skin inflammation during flares
Why this matches
During an active flare, omega-3s' anti-inflammatory action is most immediately relevant to reducing redness and scaling.
Why try it
Supported by a systematic review, omega-3 fatty acids help modulate the inflammatory pathways that drive psoriatic skin changes.
Dose or use
1,000–3,000 mg EPA+DHA daily with food
Time to results
Typically 4–12 weeks
Key study
Systematic review (2026, PMID 41534196): Therapeutic approach with fatty acids in psoriasis: A systematic review.
Caution
May thin blood at high doses; check with a doctor if on blood thinners or before surgery.
Aloe Vera Topical
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
Soothing topical gel with RCT support for plaque psoriasis
Why this matches
During a flare, aloe vera gel is a gentle topical you can apply to red, scaly patches — and unlike many soothing gels, it has randomized-trial support in mild-to-moderate plaque psoriasis.
Why try it
In a randomized, double-blind trial in mild-to-moderate plaque psoriasis, topical aloe vera cream reduced skin severity at least as much as a topical steroid over 8 weeks. It is a low-risk, soothing option for calming psoriatic patches.
Dose or use
Apply pure aloe vera gel to affected skin 1-3 times daily.
Time to results
Soothing relief is often quick; measurable improvement over about 8 weeks.
Key study
Randomized Controlled Trial (2010, PMID 19686327): in 80 patients with mild-to-moderate plaque psoriasis, topical aloe vera cream reduced psoriasis severity (PASI) at least as effectively as 0.1% triamcinolone (a topical steroid) over 8 weeks.
Caution
Use plain aloe without added fragrance or alcohol, and patch-test first, as some people react to aloe.
Topical Vitamin B12
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Topical cream that soothes flaring, scaly skin
Why this matches
When your skin is actively flaring, a topical you apply directly can calm irritation and slow the fast skin-cell turnover behind scaly patches.
Why try it
Topical vitamin B12 (cobalamin) cream has been studied for psoriasis, where it helped slow excessive skin-cell turnover and soothe irritation.
Dose or use
Apply a thin layer of a cobalamin (B12) cream to affected areas as directed on the product.
Time to results
Often within a few weeks of regular use.
Key study
Clinical study (Clinical Interventions in Aging, 2021): topical vitamin B12 (cobalamin) cream helped slow excessive skin-cell turnover and soothe irritation in psoriasis.
Caution
For external use only; patch-test first if you have sensitive skin, and stop if irritation worsens.

What kind of help feels like the best fit for you?

Diet and nutrition foundations, including checking for deficiencies

Mediterranean Diet
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Anti-inflammatory eating pattern for long-term control
Why this matches
A lifestyle-focused approach maps directly onto the Mediterranean diet's role as a sustained dietary strategy shown in an RCT to benefit psoriasis patients.
Why try it
The MEDIPSO randomized clinical trial supports this eating pattern — rich in vegetables, olive oil, and fish — for reducing psoriasis severity over time.
Dose or use
Follow a whole-food pattern: emphasize vegetables, legumes, fish, olive oil, and whole grains daily.
Time to results
Typically 8–16 weeks
Key study
RCT (2025, PMID 40991259): Mediterranean Diet and Patients With Psoriasis: The MEDIPSO Randomized Clinical Trial.
Caution
Check with your healthcare provider before starting, especially if you are pregnant or breastfeeding, take prescription medication, or manage a chronic condition.
Vitamin D Deficiency
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Low vitamin D is linked to psoriasis severity
Why this matches
To calm inflammation from the inside, it's worth checking vitamin D — low levels are strongly linked to psoriasis and how severe it gets.
Why try it
Vitamin D helps regulate skin-cell growth and immune activity, and deficiency is common in psoriasis. Testing and correcting a confirmed deficiency is a sensible internal step.
Dose or use
Ask your provider for a blood test (25-OH vitamin D) and correct any deficiency under their guidance.
Time to results
Weeks to months to restore healthy levels.
Key study
Vitamin D deficiency is commonly associated with psoriasis and its severity, and vitamin D pathways influence skin-cell growth. This is an observational association, not proof that supplements treat psoriasis.
Caution
Don't megadose vitamin D on your own; too much can be harmful. Correct a deficiency with provider guidance.

Evidence-backed daily supplements I can take by mouth

Omega-3 fatty acids
Supported by smaller clinical studies (Evidence grade B · No traditional record)
Calms skin inflammation during flares
Why this matches
During an active flare, omega-3s' anti-inflammatory action is most immediately relevant to reducing redness and scaling.
Why try it
Supported by a systematic review, omega-3 fatty acids help modulate the inflammatory pathways that drive psoriatic skin changes.
Dose or use
1,000–3,000 mg EPA+DHA daily with food
Time to results
Typically 4–12 weeks
Key study
Systematic review (2026, PMID 41534196): Therapeutic approach with fatty acids in psoriasis: A systematic review.
Caution
May thin blood at high doses; check with a doctor if on blood thinners or before surgery.
Curcumin
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
RCT-supported oral curcumin as an add-on for plaque psoriasis
Why this matches
For those exploring natural remedies, curcumin from turmeric has both a long traditional history for inflammatory skin concerns and randomized-trial support as an add-on for plaque psoriasis.
Why try it
In a randomized, double-blind, placebo-controlled trial, adding a well-absorbed oral curcumin to standard topical care led to greater improvement in psoriasis severity than topical care alone. It works through anti-inflammatory pathways and is best used as a complement to, not a replacement for, your usual treatment.
Dose or use
Trials used a bioavailable (lecithin-formulated) oral curcumin at about 2 g daily with food. Follow product labeling and consult a healthcare practitioner.
Time to results
Typically 8–12 weeks
Key study
Randomized Controlled Trial (2015, PMID 26090395): a double-blind, placebo-controlled trial in mild-to-moderate psoriasis vulgaris found that adding bioavailable oral curcumin (2 g/day) to topical steroids improved psoriasis severity (PASI) more than topical steroids alone over 12 weeks.
Caution
May interact with blood thinners; avoid high doses in pregnancy or with gallbladder issues.
Probiotics (Lactobacillus plantarum P8)
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Gut-immune support; strain data limited
Why this matches
Targeting internal inflammation makes gut-microbiome support relevant, since the gut-skin immune connection plays a role in psoriasis.
Why try it
A systematic review and meta-analysis found probiotics as a class may reduce psoriasis severity via the gut-immune (gut-skin) axis. P8 is one immune-modulating strain within that class, not the specific strain trialed for psoriasis.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Systematic review & meta-analysis (2024, PMID 38551321): probiotic supplementation may reduce psoriasis severity. Evidence is for probiotics as a category; strain-specific human data for P8 in psoriasis is limited.
Caution
Generally well tolerated; consult a doctor if immunocompromised.

Something I apply right to the skin to soothe the patches

Aloe Vera Topical
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
Soothing topical gel with RCT support for plaque psoriasis
Why this matches
During a flare, aloe vera gel is a gentle topical you can apply to red, scaly patches — and unlike many soothing gels, it has randomized-trial support in mild-to-moderate plaque psoriasis.
Why try it
In a randomized, double-blind trial in mild-to-moderate plaque psoriasis, topical aloe vera cream reduced skin severity at least as much as a topical steroid over 8 weeks. It is a low-risk, soothing option for calming psoriatic patches.
Dose or use
Apply pure aloe vera gel to affected skin 1-3 times daily.
Time to results
Soothing relief is often quick; measurable improvement over about 8 weeks.
Key study
Randomized Controlled Trial (2010, PMID 19686327): in 80 patients with mild-to-moderate plaque psoriasis, topical aloe vera cream reduced psoriasis severity (PASI) at least as effectively as 0.1% triamcinolone (a topical steroid) over 8 weeks.
Caution
Use plain aloe without added fragrance or alcohol, and patch-test first, as some people react to aloe.
Topical Vitamin B12
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Topical cream that soothes flaring, scaly skin
Why this matches
When your skin is actively flaring, a topical you apply directly can calm irritation and slow the fast skin-cell turnover behind scaly patches.
Why try it
Topical vitamin B12 (cobalamin) cream has been studied for psoriasis, where it helped slow excessive skin-cell turnover and soothe irritation.
Dose or use
Apply a thin layer of a cobalamin (B12) cream to affected areas as directed on the product.
Time to results
Often within a few weeks of regular use.
Key study
Clinical study (Clinical Interventions in Aging, 2021): topical vitamin B12 (cobalamin) cream helped slow excessive skin-cell turnover and soothe irritation in psoriasis.
Caution
For external use only; patch-test first if you have sensitive skin, and stop if irritation worsens.

Traditional practices and newer, exploratory options I'm curious about

Curcumin
Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple
RCT-supported oral curcumin as an add-on for plaque psoriasis
Why this matches
For those exploring natural remedies, curcumin from turmeric has both a long traditional history for inflammatory skin concerns and randomized-trial support as an add-on for plaque psoriasis.
Why try it
In a randomized, double-blind, placebo-controlled trial, adding a well-absorbed oral curcumin to standard topical care led to greater improvement in psoriasis severity than topical care alone. It works through anti-inflammatory pathways and is best used as a complement to, not a replacement for, your usual treatment.
Dose or use
Trials used a bioavailable (lecithin-formulated) oral curcumin at about 2 g daily with food. Follow product labeling and consult a healthcare practitioner.
Time to results
Typically 8–12 weeks
Key study
Randomized Controlled Trial (2015, PMID 26090395): a double-blind, placebo-controlled trial in mild-to-moderate psoriasis vulgaris found that adding bioavailable oral curcumin (2 g/day) to topical steroids improved psoriasis severity (PASI) more than topical steroids alone over 12 weeks.
Caution
May interact with blood thinners; avoid high doses in pregnancy or with gallbladder issues.
LI11 (Quchi) - Large Intestine 11
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Acupressure point traditionally used for skin
Why this matches
If you're exploring traditional remedies, LI11 is an acupressure point used in Traditional Chinese Medicine for inflammatory skin conditions.
Why try it
In Traditional Chinese Medicine, LI11 (Quchi) is used to help clear heat and calm inflammatory skin conditions such as psoriasis. This is a traditional practice, not a clinically proven treatment.
Dose or use
Find the point at the outer end of the elbow crease; press firmly for 1-2 minutes on each arm.
Time to results
Varies; used as an ongoing complementary practice.
Key study
Traditionally used in acupressure for inflammatory skin conditions; this use has not been confirmed in controlled clinical trials.
Caution
Acupressure is a complement, not a replacement for medical care; avoid pressing on broken or inflamed skin.
Nicotinamide riboside
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)
Emerging NAD+ research; not yet proven
Why this matches
For those focused on internal inflammation, nicotinamide riboside is being explored for the Th17 immune pathway involved in psoriasis, though the evidence is still early.
Why try it
Early, mechanistic research suggests boosting NAD+ may influence the Th17 inflammatory pathway relevant to psoriasis. Human efficacy for psoriasis is not established, so treat this as experimental.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–12 weeks
Key study
Early, mechanistic research only: NAD+ augmentation may affect Th17 (SLIT2/ROBO1) inflammatory signaling relevant to psoriasis. Not yet confirmed in human clinical trials for psoriasis.
Caution
Research is still emerging; discuss with a healthcare provider before use.
Berberine
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Explored via the gut-inflammation (gut-skin) axis
Why this matches
For a natural-remedy approach, berberine is an exploratory option — used mainly for metabolic and gut health and studied for inflammation via the gut-skin axis rather than as a skin remedy.
Why try it
Berberine has documented anti-inflammatory, antimicrobial, and metabolic actions. Any role in psoriasis is exploratory and works through gut and systemic inflammation, not an established skin-specific tradition.
Dose or use
Follow product labeling; consult a healthcare practitioner.
Time to results
Typically 4–8 weeks
Key study
Used traditionally for metabolic and digestive health; its use for psoriasis is exploratory and has not been confirmed in controlled clinical trials.
Caution
Not recommended during pregnancy; may interact with certain medications — consult a healthcare provider.

What's your main focus for your psoriasis right now?

I want to calm the inflammation driving it from the inside out

Vitamin D Deficiency

I'd like to explore natural and traditional remedies alongside my routine

LI11 (Quchi) - Large Intestine 11

I'm building lasting diet and lifestyle habits to keep flares away

Vitamin D Deficiency

My skin is flaring right now — I want to soothe the red, scaly, itchy patches

What kind of help feels like the best fit for you?

Diet and nutrition foundations, including checking for deficiencies

Vitamin D Deficiency

Evidence-backed daily supplements I can take by mouth

Something I apply right to the skin to soothe the patches

Traditional practices and newer, exploratory options I'm curious about

LI11 (Quchi) - Large Intestine 11

Natural remedies for Psoriasis

The evidence behind Psoriasis, in one page

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What's your main focus for your psoriasis right now?

I want to calm the inflammation driving it from the inside out

Vitamin D Deficiency

I'd like to explore natural and traditional remedies alongside my routine

LI11 (Quchi) - Large Intestine 11

I'm building lasting diet and lifestyle habits to keep flares away

Vitamin D Deficiency

My skin is flaring right now — I want to soothe the red, scaly, itchy patches

What kind of help feels like the best fit for you?

Diet and nutrition foundations, including checking for deficiencies

Vitamin D Deficiency

Evidence-backed daily supplements I can take by mouth

Something I apply right to the skin to soothe the patches

Traditional practices and newer, exploratory options I'm curious about

LI11 (Quchi) - Large Intestine 11

Natural remedies for Psoriasis

The evidence behind Psoriasis, in one page