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Red vine

Best studied for: Chronic venous insufficiency (poor blood flow in the leg veins); Heavy, aching legs; Mild leg swelling (oedema).

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What is Red vine? Red vine is the leaf of the common grapevine, Vitis vinifera. The French name is vigne rouge. Red-leaved types are picked in autumn, when the leaves turn deep red. It is sold mainly for tired, heavy, swollen legs. European folk use also pointed it at varicose veins and piles. Long use in tradition is not proof that it works, and it is not proof that it is safe. Here is the short verdict. A standard leaf extract has reduced leg swelling in several human trials. The trials are few, fairly short, and many were paid for by the maker. How does Red vine work? The main idea is that red vine leaf helps leaky leg veins hold fluid better. In cell and animal studies, its flavonoids appear to tighten the walls of small blood vessels. They also seem to calm inflammation in those vessels. Less fluid then leaks into the tissue of the lower leg. In people, the tested extract has lowered the measured volume of swollen lower legs. It does not remove varicose veins. Whether it slows vein disease over years is not known. What forms does Red vine come in? The form with human evidence behind it is the standard dry leaf extract, taken by mouth. - Capsules or tablets of red vine leaf extract. - Dried leaf for tea or a leg soak. - Tincture, the leaf steeped in alcohol. You will also find these on the shelf. - Gels, sprays and creams for the legs. - Blends with horse chestnut or butcher's broom. Skin gels can feel cooling and pleasant. Cooling is not the same as treating. The trials used capsules, not gels, teas or blends. Blended products also make it hard to know what, if anything, is acting. Where it comes from: European folk healers used red vine leaf for heavy legs and visible veins. In France it was known as vigne rouge and brewed as a tea. Leaf baths and compresses were laid on tired legs and on piles. Grape leaves were also eaten and used for bleeding and loose bowels. Modern interest began in Germany, where a leaf extract was made for vein complaints. These older uses were handed down by habit, not tested the way medicines are tested now.

Helps

What does Red vine help with? Chronic venous insufficiency (poor blood flow in the leg veins): This is the one use with real human data. Randomised trials of a standard leaf extract showed smaller lower legs and less aching over 6 to 12 weeks . The effect was modest, and the trials were small and mostly industry funded. Tired, heavy, aching legs: Folk use in France treated this with leaf tea and leg baths. Trial takers did report lighter, less tired legs more often than those on a dummy pill. Symptom scores are easily swayed by hope, so read the result with care. Mild leg swelling (oedema): Trials measured leg volume and found a small drop with the extract. It was tested in mild to moderate vein disease only. Swelling from heart, kidney or liver problems needs a doctor, not a supplement. Varicose veins: Tradition claimed the leaf shrank bulging veins. There is no good evidence that it changes a varicose vein. At best it may ease the aching and swelling around one. Haemorrhoids (piles): Folk healers used leaf washes and sitz baths for piles. Human evidence for red vine leaf here is very thin. Bleeding from the back passage always needs checking by a doctor. Easy bruising and spider veins: The idea is that flavonoids strengthen tiny vessels. That has been seen in lab work, not proven in people. No reliable trial shows fewer bruises or faded spider veins.

Red vine

Quick Facts

  • What it is: Red vine is the autumn leaf of the grapevine, used in Europe for tired, swollen legs.
  • Main uses: Chronic venous insufficiency (poor blood flow in the leg veins), Heavy, aching legs, Mild leg swelling (oedema)
  • Active ingredients: Quercetin glucuronide, Isoquercitrin, Kaempferol glycosides, Anthocyanins, Proanthocyanidins
  • Forms: Extract capsules or tablets, Dried leaf tea, Tincture, Leg gels and sprays
  • Time to effect: About 6 weeks in trials; may do nothing
  • Side effects: Mostly mild stomach upset, headache or itching; allergy is possible.
  • Pregnancy & breastfeeding: Avoid in pregnancy and while breastfeeding.

Educational information, not medical advice — ask your doctor or midwife.

What is Red vine?

Red vine is the leaf of the common grapevine, Vitis vinifera. The French name is vigne rouge. Red-leaved types are picked in autumn, when the leaves turn deep red.

It is sold mainly for tired, heavy, swollen legs. European folk use also pointed it at varicose veins and piles. Long use in tradition is not proof that it works, and it is not proof that it is safe.

Here is the short verdict. A standard leaf extract has reduced leg swelling in several human trials. The trials are few, fairly short, and many were paid for by the maker.

How does Red vine work?

The main idea is that red vine leaf helps leaky leg veins hold fluid better.

In cell and animal studies, its flavonoids appear to tighten the walls of small blood vessels. They also seem to calm inflammation in those vessels. Less fluid then leaks into the tissue of the lower leg.

In people, the tested extract has lowered the measured volume of swollen lower legs. It does not remove varicose veins. Whether it slows vein disease over years is not known.

What forms does Red vine come in?

The form with human evidence behind it is the standard dry leaf extract, taken by mouth.

- Capsules or tablets of red vine leaf extract. - Dried leaf for tea or a leg soak. - Tincture, the leaf steeped in alcohol.

You will also find these on the shelf.

- Gels, sprays and creams for the legs. - Blends with horse chestnut or butcher's broom.

Skin gels can feel cooling and pleasant. Cooling is not the same as treating.

The trials used capsules, not gels, teas or blends. Blended products also make it hard to know what, if anything, is acting.

Where it comes from:

European folk healers used red vine leaf for heavy legs and visible veins. In France it was known as vigne rouge and brewed as a tea. Leaf baths and compresses were laid on tired legs and on piles.

Grape leaves were also eaten and used for bleeding and loose bowels. Modern interest began in Germany, where a leaf extract was made for vein complaints.

These older uses were handed down by habit, not tested the way medicines are tested now.

Who should avoid Red vine?

  • Never use red vine for sudden swelling, pain or redness in one leg; that can be a blood clot in a deep vein (DVT) and needs same-day medical care.
  • Do not use if you are allergic to grapes, grape leaves, raisins or wine.
  • Do not use if you are pregnant or breastfeeding, because safety has not been shown.
  • Do not give it to children.
  • Do not use if you take warfarin or another blood thinner (anticoagulant), unless the doctor who manages it agrees.
  • Do not use it to self-treat swelling caused by heart, kidney or liver disease; see your doctor instead.
  • Avoid it in the two weeks before planned surgery unless your surgeon says it is fine.
  • Do not use it instead of compression stockings or treatment your doctor has advised.

When should you see a doctor?

Stop and see a doctor if you get a rash, itching or stomach upset that does not settle.

Get urgent care for swelling of the face, lips or throat, or for trouble breathing.

See a doctor the same day for one leg that is suddenly swollen, hot, red or painful. Book an appointment for skin changes, weeping or an open sore near the ankle, for bleeding from the back passage, or for breathlessness with swollen legs.

Is Red vine legal where you live?

In the EU and UK, red vine leaf is sold as a food supplement or a traditional herbal product. The European Medicines Agency has published a herbal monograph on the leaf. In the United States it is an ordinary dietary supplement and is not approved to treat any disease.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

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