Jin Guo Lan

A long-standing staple of Chinese medicine for sore throat, but human trial evidence is absent; the evidence grade is insufficient.

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What is Jin Guo Lan? Jin Guo Lan is a herb used in Traditional Chinese Medicine for a hot, sore, swollen throat. It is the dried tuber of Tinospora sagittata. A tuber is an underground storage root. The plant is a climbing vine from southern China. It is also used for mouth ulcers. And it is used for hot, painful stomach upset. It is a single drug (TCM). That means one herb used on its own, not a multi-herb formula. In practice it is often added to formulas. It is taken as a bitter decoction, a tea made by simmering the root. It can also be taken as a powder. It is sometimes put on the skin over boils, insect bites and snake bites. On the evidence: we could find no published human trials of Jin Guo Lan. Its standing rests on long recorded use in Chinese medicine. Lab and animal work backs that up. Long use tells you what people have done for many years. It is not proof that the herb works. That point applies everywhere in this document. How does Jin Guo Lan work? In TCM terms, Jin Guo Lan is bitter and cold. It is said to clear heat, resolve toxicity and ease pain. That is the old way of describing a remedy for red, hot, swollen, painful problems. In lab terms, the tuber holds bitter diterpene lactones. It also holds berberine-like alkaloids. These are plant compounds also found in goldthread and barberry. In test tubes and in animals, these compounds slow the growth of some bacteria. They also cut inflammation (swelling and irritation). That is a fair starting point. It does not explain what happens in a person. No human trial has shown that the root does these things in your throat or stomach. What forms does Jin Guo Lan come in? Jin Guo Lan is sold as: Dried sliced tuber, simmered into a decoction (a strong tea made by boiling the root). Powdered root, in capsules or loose. It is sometimes mixed into throat lozenges or gargles. Granules or strong extracts made up by a herbal pharmacy. A paste made from the fresh or powdered root. In traditional practice this is put on the skin. It also turns up as one part of multi-herb Chinese patent medicines for sore throat. Where it comes from: Jin Guo Lan shows up in Chinese herbal writing from the Qing dynasty onward. That includes the 18th-century Ben Cao Gang Mu Shi Yi, a supplement to the great Ming herbal. It is listed in the modern Chinese Pharmacopoeia. Its classic job has always been the same: a hot, sore, swollen throat. Folk use in southern China goes further. Several ethnic minority traditions use it for stomach pain, boils and snakebite.

Helps

What does Jin Guo Lan help with? Sore throat with redness and swelling: This is the main traditional use and the one most TCM texts name first. The root is simmered and drunk, or powdered and used as a gargle. No human trial has tested Jin Guo Lan for sore throat. A sore throat that lasts more than a week, comes with a high fever, or makes swallowing or breathing hard needs a doctor, not a herb. Mouth ulcers and inflamed gums: Traditionally the powder is applied to the sore spot or used as a mouth rinse for small painful ulcers. There is no human trial evidence. Laboratory work shows some of its compounds slow bacterial growth in a dish, which is a long way from healing a mouth ulcer. Tonsillitis (swollen, infected tonsils) as a traditional adjunct: Chinese clinical writing describes Jin Guo Lan inside multi-herb throat formulas. Because those are mixtures, nothing can be credited to this root on its own. Bacterial tonsillitis can need antibiotics. Do not use this herb in place of care for a high fever or severe throat pain. Stomach pain described in TCM as hot: Traditional use covers burning stomach pain with a bitter taste and thirst. TCM explicitly warns it is wrong for the opposite pattern — a cold, weak digestion with loose stools. No human trial evidence exists. The herb is very bitter and cold in TCM terms and can itself upset the stomach. Boils and skin abscesses, applied traditionally to the skin: The root is ground with water or vinegar and spread on the swelling in folk practice. There is no trial evidence. A spreading red area, fever or a boil that needs draining is a matter for a doctor. Insect and snake bites, as a traditional first-aid poultice: Folk traditions in southern China record the fresh root applied to bites. This is historical record only. Never treat a venomous snakebite with a herb. That is a medical emergency — call emergency services and get to hospital.

Jin Guo Lan

Jin Guo Lan

Quick Facts

  • What it is: Jin Guo Lan is the bitter dried tuber of the Chinese vine Tinospora sagittata, used in Traditional Chinese Medicine mainly for hot, swollen sore throats.
  • Main uses: Sore throat with redness and swelling, Mouth ulcers and inflamed gums, Hot stomach pain in TCM terms, Boils and bites, applied to the skin traditionally
  • Best for: Short-term traditional use for an acute sore throat, under a practitioner's guidance
  • Active ingredients: Columbin and isocolumbin (bitter diterpene lactones), Tinosporide, Fibleucin, Palmatine (a berberine-like alkaloid), Jatrorrhizine (a berberine-like alkaloid)
  • Forms: Dried sliced tuber for decoction, Powder, loose or in capsules, Granules and concentrated extracts, Topical paste, Ingredient in multi-herb throat products
  • Time to effect: Not established; traditional use is short-term for acute throat pain.
  • Side effects: Mostly nausea, stomach ache and loose stools; serious concerns centre on pregnancy, newborns and drug interactions.

What is Jin Guo Lan?

Jin Guo Lan is a herb used in Traditional Chinese Medicine for a hot, sore, swollen throat.

It is the dried tuber of Tinospora sagittata. A tuber is an underground storage root. The plant is a climbing vine from southern China.

It is also used for mouth ulcers. And it is used for hot, painful stomach upset.

It is a single drug (TCM). That means one herb used on its own, not a multi-herb formula. In practice it is often added to formulas.

It is taken as a bitter decoction, a tea made by simmering the root. It can also be taken as a powder. It is sometimes put on the skin over boils, insect bites and snake bites.

On the evidence: we could find no published human trials of Jin Guo Lan. Its standing rests on long recorded use in Chinese medicine. Lab and animal work backs that up.

Long use tells you what people have done for many years. It is not proof that the herb works. That point applies everywhere in this document.

How does Jin Guo Lan work?

In TCM terms, Jin Guo Lan is bitter and cold. It is said to clear heat, resolve toxicity and ease pain. That is the old way of describing a remedy for red, hot, swollen, painful problems.

In lab terms, the tuber holds bitter diterpene lactones. It also holds berberine-like alkaloids. These are plant compounds also found in goldthread and barberry.

In test tubes and in animals, these compounds slow the growth of some bacteria. They also cut inflammation (swelling and irritation).

That is a fair starting point. It does not explain what happens in a person. No human trial has shown that the root does these things in your throat or stomach.

What forms does Jin Guo Lan come in?

Jin Guo Lan is sold as:

Dried sliced tuber, simmered into a decoction (a strong tea made by boiling the root).

Powdered root, in capsules or loose. It is sometimes mixed into throat lozenges or gargles.

Granules or strong extracts made up by a herbal pharmacy.

A paste made from the fresh or powdered root. In traditional practice this is put on the skin.

It also turns up as one part of multi-herb Chinese patent medicines for sore throat.

Where it comes from:

Jin Guo Lan shows up in Chinese herbal writing from the Qing dynasty onward. That includes the 18th-century Ben Cao Gang Mu Shi Yi, a supplement to the great Ming herbal. It is listed in the modern Chinese Pharmacopoeia.

Its classic job has always been the same: a hot, sore, swollen throat.

Folk use in southern China goes further. Several ethnic minority traditions use it for stomach pain, boils and snakebite.

Who should avoid Jin Guo Lan?

  • Do not use if you are pregnant or trying to become pregnant: the berberine-like alkaloids in this root may stimulate the womb.
  • Do not use if you are breastfeeding, because these alkaloids can pass into breast milk.
  • Never give this herb to a newborn or young infant: berberine-type alkaloids can worsen jaundice (yellowing of the skin and eyes) and in severe cases damage the developing brain.
  • Do not use if you take ciclosporin, tacrolimus or any other anti-rejection medicine after a transplant.
  • Do not use if you take warfarin or any other blood thinner.
  • Do not use if you take medicine for diabetes, unless your doctor is monitoring your blood sugar.
  • Do not use if you have a weak, cold digestion with long-term loose stools, poor appetite or a bloated stomach — TCM regards this herb as wrong for that pattern.
  • Do not use if you have liver or kidney disease, because this herb has never been tested for safety in people with those conditions.
  • Do not use it in place of antibiotics or emergency care for a severe throat infection, a spreading skin infection or a snakebite.
  • Do not use if you take any prescription medicine without first checking with your doctor or pharmacist.

When should you see a doctor?

See a doctor promptly if your sore throat lasts more than a week, comes with a fever above 38.5C, or makes it hard to swallow your own saliva. Go to hospital or call emergency services if you have trouble breathing, your neck or face swells, or you are drooling and cannot swallow.

Stop the herb and get medical advice if you vomit repeatedly, have ongoing diarrhoea, notice yellowing of your skin or eyes, or feel faint and dizzy. Anyone bitten by a snake needs emergency care immediately, not a herbal remedy.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

The evidence behind this remedy, in one page

What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.

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