Reduces antibiotic-related gut side effects

Why this matches

This option is ideal for those wanting to protect gut comfort and reduce diarrhea and digestive upset that can accompany standard H. pylori treatment.

Why try it

Supported by a randomized controlled trial finding Saccharomyces boulardii added to standard quadruple therapy improved eradication safety and reduced gastrointestinal side effects.

Dose or use

Follow product labeling; consult a healthcare practitioner.

Time to results

Typically 1–2 weeks for side effect relief

Key study

Meta-analysis (2025, PMID 41247686): Efficacy and Safety of <em>Saccharomyces Boulardii</em> with Standard Quadruple Therapy for Eradication of <em>Helicobacter Pylori </em>in Adults: Meta-Analysis.

Caution

Use with caution if immunocompromised or have a central venous catheter; consult your doctor first.

Boosts eradication rates alongside antibiotics

Why this matches

If you're taking antibiotics for H. pylori, adding a probiotic is one of the best-studied ways to support the treatment. Research on probiotics as a group, including strains like L. plantarum P8, links them to better eradication and easier-to-tolerate courses.

Why try it

A 2025 systematic review of probiotics as a class (not this strain alone) found that adding them to standard bismuth-based antibiotic therapy improved eradication success and tolerability. L. plantarum P8 is one well-characterized strain within that broader probiotic class.

Dose or use

Follow product labeling; consult a healthcare practitioner.

Time to results

Typically assessed at end of treatment course (2–4 weeks)

Key study

Systematic review and meta-analysis (2025, PMID 41574348): probiotics as a class, added to bismuth-containing quadruple therapy, improved H. pylori eradication and tolerability. Note: L. plantarum P8 was not tested individually in this review; it is one representative strain of the probiotic class studied.

Caution

Take a few hours apart from antibiotics for best effect; consult your doctor if immunocompromised.

Soothes and coats the stomach lining

Why this matches

If treatment leaves your stomach raw or uncomfortable, deglycyrrhizinated licorice (DGL) is traditionally taken to soothe and protect the gastric lining while you get through your course.

Why try it

Licorice has a long history of use for soothing the stomach lining, and DGL is the form with the glycyrrhizin removed so it doesn't raise blood pressure the way whole licorice can. This is a traditional gut-comfort use rather than a proven H. pylori treatment.

Dose or use

Typically chewed as a tablet before meals; follow product labeling and consult a healthcare practitioner.

Time to results

Often used for day-to-day comfort during treatment

Key study

Traditionally used to soothe and protect the stomach lining; this specific use for H. pylori has not been confirmed in controlled clinical trials.

Caution

Use the DGL (deglycyrrhizinated) form; ordinary licorice can raise blood pressure and lower potassium. Check with your doctor if you have heart or blood-pressure concerns.

Natural protein with antimicrobial properties

Why this matches

For those interested in natural antimicrobial support, lactoferrin has been studied as a complementary addition to H. pylori eradication regimens.

Why try it

Supported by a randomized controlled trial comparing lactoferrin-containing regimens for H. pylori eradication, suggesting it may help address antibiotic-resistance challenges.

Dose or use

Follow product labeling; consult a healthcare practitioner.

Time to results

Typically 2–4 weeks

Key study

RCT (2026, PMID 42340765): Helicobacter pylori Eradication in the Era of Rising Antibiotic Resistance: A Randomized Controlled Comparison of Clarithromycin- and Levofloxacin-Based Triple Therapy with or without Lactoferrin.

Caution

Generally well tolerated; consult a healthcare practitioner if you have a milk protein allergy.

Classic tree-resin remedy for the gut

Why this matches

If you're looking at natural options alongside your care, mastic gum (Chios mastic, from the Pistacia lentiscus tree) is the most traditional resin used for the stomach and H. pylori-type discomfort.

Why try it

Mastic gum has centuries of traditional use for stomach and digestive complaints and is the natural agent most associated with H. pylori. We include it on that traditional basis rather than a specific trial in our library.

Dose or use

Commonly taken as capsules of resin with or before meals; follow product labeling and consult a healthcare practitioner.

Time to results

Traditionally used over a several-week course

Key study

Traditionally used for stomach complaints and H. pylori; this specific use has not been confirmed in a controlled clinical trial in our library.

Caution

Generally well tolerated; stop and check with your doctor if it upsets your stomach, and don't use it as a substitute for prescribed eradication therapy.

Sulforaphane-rich sprout concentrate

Why this matches

For a food-derived natural option, broccoli sprout extract concentrates sulforaphane, the compound in cruciferous vegetables that has drawn interest for supporting the stomach lining alongside H. pylori care.

Why try it

Broccoli sprouts are a rich natural source of sulforaphane and are commonly explored for gut and stomach-lining support. We include this on a general, food-based rationale rather than a specific trial in our library.

Dose or use

Taken as a standardized sprout extract; follow product labeling and consult a healthcare practitioner.

Time to results

Typically used over several weeks

Key study

A food-derived source of sulforaphane explored for stomach-lining support; this specific use has not been confirmed in a controlled clinical trial in our library.

Caution

Generally well tolerated as a food-based supplement; it is a complement to, not a replacement for, prescribed eradication therapy.

Natural protein with antimicrobial properties

Why this matches

For those interested in natural antimicrobial support, lactoferrin has been studied as a complementary addition to H. pylori eradication regimens.

Why try it

Supported by a randomized controlled trial comparing lactoferrin-containing regimens for H. pylori eradication, suggesting it may help address antibiotic-resistance challenges.

Dose or use

Follow product labeling; consult a healthcare practitioner.

Time to results

Typically 2–4 weeks

Key study

RCT (2026, PMID 42340765): Helicobacter pylori Eradication in the Era of Rising Antibiotic Resistance: A Randomized Controlled Comparison of Clarithromycin- and Levofloxacin-Based Triple Therapy with or without Lactoferrin.

Caution

Generally well tolerated; consult a healthcare practitioner if you have a milk protein allergy.

Boosts eradication rates alongside antibiotics

Why this matches

If you're taking antibiotics for H. pylori, adding a probiotic is one of the best-studied ways to support the treatment. Research on probiotics as a group, including strains like L. plantarum P8, links them to better eradication and easier-to-tolerate courses.

Why try it

A 2025 systematic review of probiotics as a class (not this strain alone) found that adding them to standard bismuth-based antibiotic therapy improved eradication success and tolerability. L. plantarum P8 is one well-characterized strain within that broader probiotic class.

Dose or use

Follow product labeling; consult a healthcare practitioner.

Time to results

Typically assessed at end of treatment course (2–4 weeks)

Key study

Systematic review and meta-analysis (2025, PMID 41574348): probiotics as a class, added to bismuth-containing quadruple therapy, improved H. pylori eradication and tolerability. Note: L. plantarum P8 was not tested individually in this review; it is one representative strain of the probiotic class studied.

Caution

Take a few hours apart from antibiotics for best effect; consult your doctor if immunocompromised.

H. pylori can leave you low on iron

Why this matches

Chronic H. pylori can quietly lower your iron, so if you're focused on repairing nutritional gaps, iron is one of the first things worth checking.

Why try it

Long-standing H. pylori gastritis can reduce iron absorption and cause slow blood loss, and it's a recognized cause of unexplained iron-deficiency anemia. Flagging it here helps you and your doctor look in the right place.

Dose or use

Ask your doctor to check ferritin and iron levels; correct any deficiency with diet or supplements under guidance rather than guessing.

Time to results

Iron stores typically rebuild over 1-3 months once corrected

Key study

Chronic H. pylori is a recognized cause of iron-deficiency anemia; this card flags the association so levels can be checked, and is educational rather than tied to a specific trial in our library.

Caution

Don't start high-dose iron on your own; too much iron is harmful and levels should be confirmed by a blood test first.

H. pylori can impair B12 absorption

Why this matches

If you're addressing nutrient gaps, vitamin B12 is worth checking too: long-term H. pylori can interfere with how your stomach absorbs it.

Why try it

Chronic H. pylori gastritis can lower stomach acid and intrinsic factor, both needed to absorb B12, making it a well-documented cause of B12 deficiency. Surfacing it helps you catch a fixable gap early.

Dose or use

Ask your doctor to check your B12 (and ideally methylmalonic acid) levels; replete through diet, oral supplements, or injections as advised.

Time to results

Symptoms and levels usually improve over weeks to a few months once corrected

Key study

H. pylori-associated atrophic gastritis is an established cause of B12 malabsorption; this card flags the association for testing and is educational rather than tied to a specific trial in our library.

Caution

Confirm low B12 with a blood test before treating; persistent numbness or tingling should be reviewed by a doctor promptly.

Soothes and coats the stomach lining

Why this matches

If treatment leaves your stomach raw or uncomfortable, deglycyrrhizinated licorice (DGL) is traditionally taken to soothe and protect the gastric lining while you get through your course.

Why try it

Licorice has a long history of use for soothing the stomach lining, and DGL is the form with the glycyrrhizin removed so it doesn't raise blood pressure the way whole licorice can. This is a traditional gut-comfort use rather than a proven H. pylori treatment.

Dose or use

Typically chewed as a tablet before meals; follow product labeling and consult a healthcare practitioner.

Time to results

Often used for day-to-day comfort during treatment

Key study

Traditionally used to soothe and protect the stomach lining; this specific use for H. pylori has not been confirmed in controlled clinical trials.

Caution

Use the DGL (deglycyrrhizinated) form; ordinary licorice can raise blood pressure and lower potassium. Check with your doctor if you have heart or blood-pressure concerns.

Acupressure point for stomach discomfort

Why this matches

If your main problem is stomach discomfort, gastritis or nausea, REN12 (Zhongwan) is the traditional acupressure point on the upper-belly midline used for exactly that kind of digestive upset.

Why try it

In traditional Chinese medicine REN12 is a primary point for bloating, indigestion, gastritis and nausea. It's a gentle self-care comfort measure, not a way to clear the infection.

Dose or use

Press gently with a fingertip on the midline about halfway between the navel and the base of the breastbone for 1-2 minutes; avoid right after a large meal.

Time to results

Used in the moment for comfort

Key study

A traditional acupressure point for stomach discomfort, gastritis and nausea; used for comfort and not confirmed to affect H. pylori itself.

Caution

For symptom comfort only; it does not treat or eradicate H. pylori. Avoid firm pressure if the area is very tender or you are pregnant, and keep taking any prescribed treatment.

Leg acupressure point for digestion

Why this matches

When your stomach feels off or queasy, ST36 (Zusanli), just below the knee, is one of the most-used acupressure points for supporting digestion and easing nausea.

Why try it

ST36 is a mainstay Stomach-meridian point in traditional Chinese medicine for indigestion, bloating and nausea. It's a simple self-care comfort technique, not an antimicrobial.

Dose or use

Press firmly with a fingertip about four finger-widths below the kneecap, just outside the shinbone, for 1-2 minutes on each leg.

Time to results

Used in the moment for comfort

Key study

A traditional acupressure point used to support digestion and ease nausea; a comfort measure, not confirmed to affect H. pylori.

Caution

For symptom comfort only; it does not treat the infection. Continue any prescribed eradication therapy.

Reduces antibiotic-related gut side effects

Why this matches

This option is ideal for those wanting to protect gut comfort and reduce diarrhea and digestive upset that can accompany standard H. pylori treatment.

Why try it

Supported by a randomized controlled trial finding Saccharomyces boulardii added to standard quadruple therapy improved eradication safety and reduced gastrointestinal side effects.

Dose or use

Follow product labeling; consult a healthcare practitioner.

Time to results

Typically 1–2 weeks for side effect relief

Key study

Meta-analysis (2025, PMID 41247686): Efficacy and Safety of <em>Saccharomyces Boulardii</em> with Standard Quadruple Therapy for Eradication of <em>Helicobacter Pylori </em>in Adults: Meta-Analysis.

Caution

Use with caution if immunocompromised or have a central venous catheter; consult your doctor first.

Natural protein with antimicrobial properties

Why this matches

For those interested in natural antimicrobial support, lactoferrin has been studied as a complementary addition to H. pylori eradication regimens.

Why try it

Supported by a randomized controlled trial comparing lactoferrin-containing regimens for H. pylori eradication, suggesting it may help address antibiotic-resistance challenges.

Dose or use

Follow product labeling; consult a healthcare practitioner.

Time to results

Typically 2–4 weeks

Key study

RCT (2026, PMID 42340765): Helicobacter pylori Eradication in the Era of Rising Antibiotic Resistance: A Randomized Controlled Comparison of Clarithromycin- and Levofloxacin-Based Triple Therapy with or without Lactoferrin.

Caution

Generally well tolerated; consult a healthcare practitioner if you have a milk protein allergy.

Boosts eradication rates alongside antibiotics

Why this matches

If you're taking antibiotics for H. pylori, adding a probiotic is one of the best-studied ways to support the treatment. Research on probiotics as a group, including strains like L. plantarum P8, links them to better eradication and easier-to-tolerate courses.

Why try it

A 2025 systematic review of probiotics as a class (not this strain alone) found that adding them to standard bismuth-based antibiotic therapy improved eradication success and tolerability. L. plantarum P8 is one well-characterized strain within that broader probiotic class.

Dose or use

Follow product labeling; consult a healthcare practitioner.

Time to results

Typically assessed at end of treatment course (2–4 weeks)

Key study

Systematic review and meta-analysis (2025, PMID 41574348): probiotics as a class, added to bismuth-containing quadruple therapy, improved H. pylori eradication and tolerability. Note: L. plantarum P8 was not tested individually in this review; it is one representative strain of the probiotic class studied.

Caution

Take a few hours apart from antibiotics for best effect; consult your doctor if immunocompromised.

Acupressure point for stomach discomfort

Why this matches

If your main problem is stomach discomfort, gastritis or nausea, REN12 (Zhongwan) is the traditional acupressure point on the upper-belly midline used for exactly that kind of digestive upset.

Why try it

In traditional Chinese medicine REN12 is a primary point for bloating, indigestion, gastritis and nausea. It's a gentle self-care comfort measure, not a way to clear the infection.

Dose or use

Press gently with a fingertip on the midline about halfway between the navel and the base of the breastbone for 1-2 minutes; avoid right after a large meal.

Time to results

Used in the moment for comfort

Key study

A traditional acupressure point for stomach discomfort, gastritis and nausea; used for comfort and not confirmed to affect H. pylori itself.

Caution

For symptom comfort only; it does not treat or eradicate H. pylori. Avoid firm pressure if the area is very tender or you are pregnant, and keep taking any prescribed treatment.

Leg acupressure point for digestion

Why this matches

When your stomach feels off or queasy, ST36 (Zusanli), just below the knee, is one of the most-used acupressure points for supporting digestion and easing nausea.

Why try it

ST36 is a mainstay Stomach-meridian point in traditional Chinese medicine for indigestion, bloating and nausea. It's a simple self-care comfort technique, not an antimicrobial.

Dose or use

Press firmly with a fingertip about four finger-widths below the kneecap, just outside the shinbone, for 1-2 minutes on each leg.

Time to results

Used in the moment for comfort

Key study

A traditional acupressure point used to support digestion and ease nausea; a comfort measure, not confirmed to affect H. pylori.

Caution

For symptom comfort only; it does not treat the infection. Continue any prescribed eradication therapy.

H. pylori can leave you low on iron

Why this matches

Chronic H. pylori can quietly lower your iron, so if you're focused on repairing nutritional gaps, iron is one of the first things worth checking.

Why try it

Long-standing H. pylori gastritis can reduce iron absorption and cause slow blood loss, and it's a recognized cause of unexplained iron-deficiency anemia. Flagging it here helps you and your doctor look in the right place.

Dose or use

Ask your doctor to check ferritin and iron levels; correct any deficiency with diet or supplements under guidance rather than guessing.

Time to results

Iron stores typically rebuild over 1-3 months once corrected

Key study

Chronic H. pylori is a recognized cause of iron-deficiency anemia; this card flags the association so levels can be checked, and is educational rather than tied to a specific trial in our library.

Caution

Don't start high-dose iron on your own; too much iron is harmful and levels should be confirmed by a blood test first.

H. pylori can impair B12 absorption

Why this matches

If you're addressing nutrient gaps, vitamin B12 is worth checking too: long-term H. pylori can interfere with how your stomach absorbs it.

Why try it

Chronic H. pylori gastritis can lower stomach acid and intrinsic factor, both needed to absorb B12, making it a well-documented cause of B12 deficiency. Surfacing it helps you catch a fixable gap early.

Dose or use

Ask your doctor to check your B12 (and ideally methylmalonic acid) levels; replete through diet, oral supplements, or injections as advised.

Time to results

Symptoms and levels usually improve over weeks to a few months once corrected

Key study

H. pylori-associated atrophic gastritis is an established cause of B12 malabsorption; this card flags the association for testing and is educational rather than tied to a specific trial in our library.

Caution

Confirm low B12 with a blood test before treating; persistent numbness or tingling should be reviewed by a doctor promptly.

Classic tree-resin remedy for the gut

Why this matches

If you're looking at natural options alongside your care, mastic gum (Chios mastic, from the Pistacia lentiscus tree) is the most traditional resin used for the stomach and H. pylori-type discomfort.

Why try it

Mastic gum has centuries of traditional use for stomach and digestive complaints and is the natural agent most associated with H. pylori. We include it on that traditional basis rather than a specific trial in our library.

Dose or use

Commonly taken as capsules of resin with or before meals; follow product labeling and consult a healthcare practitioner.

Time to results

Traditionally used over a several-week course

Key study

Traditionally used for stomach complaints and H. pylori; this specific use has not been confirmed in a controlled clinical trial in our library.

Caution

Generally well tolerated; stop and check with your doctor if it upsets your stomach, and don't use it as a substitute for prescribed eradication therapy.

Sulforaphane-rich sprout concentrate

Why this matches

For a food-derived natural option, broccoli sprout extract concentrates sulforaphane, the compound in cruciferous vegetables that has drawn interest for supporting the stomach lining alongside H. pylori care.

Why try it

Broccoli sprouts are a rich natural source of sulforaphane and are commonly explored for gut and stomach-lining support. We include this on a general, food-based rationale rather than a specific trial in our library.

Dose or use

Taken as a standardized sprout extract; follow product labeling and consult a healthcare practitioner.

Time to results

Typically used over several weeks

Key study

A food-derived source of sulforaphane explored for stomach-lining support; this specific use has not been confirmed in a controlled clinical trial in our library.

Caution

Generally well tolerated as a food-based supplement; it is a complement to, not a replacement for, prescribed eradication therapy.

Soothes and coats the stomach lining

Why this matches

If treatment leaves your stomach raw or uncomfortable, deglycyrrhizinated licorice (DGL) is traditionally taken to soothe and protect the gastric lining while you get through your course.

Why try it

Licorice has a long history of use for soothing the stomach lining, and DGL is the form with the glycyrrhizin removed so it doesn't raise blood pressure the way whole licorice can. This is a traditional gut-comfort use rather than a proven H. pylori treatment.

Dose or use

Typically chewed as a tablet before meals; follow product labeling and consult a healthcare practitioner.

Time to results

Often used for day-to-day comfort during treatment

Key study

Traditionally used to soothe and protect the stomach lining; this specific use for H. pylori has not been confirmed in controlled clinical trials.

Caution

Use the DGL (deglycyrrhizinated) form; ordinary licorice can raise blood pressure and lower potassium. Check with your doctor if you have heart or blood-pressure concerns.