Itchy blistering rash on elbows and knees

You have small bumps or tiny blisters on your elbows and knees. They itch, sting, or burn, often before you can see much. Scratching breaks them open and can leave dark or pale marks behind.

This rash tends to show up on both sides of the body. Elbows and knees are the most common spots. The scalp, lower back, and buttocks can be involved too.

One known cause is a reaction to gluten. Gluten is a protein in wheat, rye, and barley. In some people the immune system reacts to it, and the skin shows that reaction even when the gut feels fine.

When to see someone

See a doctor before you drop gluten from your diet. The blood test and small skin sample work best while you still eat it. Go sooner if the blisters ooze pus, you run a fever, or the rash spreads fast.

Below is a list of remedies people use for celiac disease, the gluten reaction behind this rash. Each one carries a grade that shows how strong the research is, not a promise of results. Bring any that interest you to your doctor first.

Celiac Disease: natural remedies and the evidence behind them

9 options · 1 graded B · 8 traditional or ungraded

What part of managing celiac disease do you want help with right now?

I'm strictly gluten-free but still get bloating, cramps or loose stools

  1. Probiotics

    Supported by smaller clinical studies (Evidence grade B · Traditional use not yet assessed)

    Adjunct for symptoms that linger

    Why this matches
    You're strict with gluten but still bloated or irregular, and that residual-symptom picture is exactly where some people add a probiotic on top of the diet, not instead of it.
    Why try it
    The library lists probiotics for IBS, inflammatory bowel disease and diarrhoea. Gut bacteria stay out of balance in many people with celiac even after they go gluten-free, and small studies suggest a probiotic can ease the bloating and irregular stools that linger. Treat it as an adjunct for comfort, not as a substitute for gluten avoidance.
    Dose or use
    Try a single, reputable multi-strain probiotic at the label dose for 4-8 weeks and judge whether your bloating and stool pattern improve. If there's no difference, stop. Keep the diet strict throughout, since ongoing symptoms are more often from hidden gluten than from bacteria.
    Time to results
    Usually 2-4 weeks if it is going to help
    Key study
    Randomized controlled trial (2019, PMID 29688915): a double-blind, placebo-controlled multicenter trial in celiac patients with IBS-type symptoms despite a strict gluten-free diet found a multispecies probiotic significantly reduced GI symptom scores (IBS-SSS and GSRS) versus placebo. The benefit was modest, and probiotics remain an adjunct for lingering symptoms, not a treatment for celiac disease itself.
    Caution
    Persistent symptoms despite a genuinely strict gluten-free diet should be checked by a clinician before you assume it's just dysbiosis, to rule out hidden gluten, lactose intolerance or another diagnosis. Choose a gluten-free-labelled product, and be cautious with probiotics if you are severely immunocompromised.
  2. Gluten Free Diet

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use

    The core treatment that lets the gut recover

    Why this matches
    You want to get the diet right, and this is the whole game in celiac: removing every source of gluten is what lets your intestinal lining recover and your symptoms settle.
    Why try it
    In celiac disease, gluten triggers an immune reaction that flattens the lining of your small intestine. Completely removing it is the accepted medical standard of care and the approach shown to let that lining recover. It works only if it is strict and lifelong, so the hard part is finding the hidden sources.
    Dose or use
    Cut out all wheat, barley and rye, and anything made from them, for life, not just when symptoms flare. Read every label for gluten and 'may contain' warnings. Watch cross-contact at home: separate toaster, chopping board, colander and butter, and wash shared surfaces. Choose oats labelled gluten-free only. A dietitian who knows celiac is worth one visit.
    Time to results
    Symptoms often ease within weeks; full gut-lining healing can take 6-24 months
    Key study
    A strict lifelong gluten-free diet is the universally accepted medical standard of care for celiac disease; it is the removal of the trigger rather than a supplement, so no single clinical trial is cited here.
    Caution
    Even small, occasional gluten exposure keeps the damage going, so 'mostly gluten-free' is not enough. Don't start the diet before you've been formally tested for celiac, because going gluten-free first can make the diagnosis unreliable. A poorly planned gluten-free diet can itself run short on fibre, iron and B vitamins, so replace what you cut.
  3. ST36 (Zusanli)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Classic point for digestive comfort

    Why this matches
    For the days you're strict but still uncomfortable, this is a second self-pressure option, on your leg rather than your belly, to help settle general gut upset.
    Why try it
    ST36 sits just below the knee on the Stomach meridian and is the best-known traditional point for digestive complaints, used for bloating, indigestion, nausea and low energy. It is a gentle self-care comfort measure grounded in tradition, not a proven treatment for celiac.
    Dose or use
    Find the spot about four finger-widths below your kneecap and one finger-width to the outer side of your shinbone, where a muscle flexes when you raise your foot. Press firmly with a thumb, small circles, for 1-2 minutes on each leg. Repeat a couple of times a day.
    Time to results
    Often gives some relief within minutes; use as needed
    Key study
    Traditionally used for digestive complaints; this specific use has not been confirmed in controlled clinical trials.
    Caution
    This is for mild, familiar digestive discomfort only, not a substitute for strict gluten avoidance or medical review of ongoing symptoms. Ease off if pressing sharpens any pain, and avoid over broken or inflamed skin. Traditionally used cautiously in pregnancy.
  4. REN12 (Zhongwan)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Self-pressure point for a bloated gut

    Why this matches
    When you're gluten-free but your stomach is still bloated or crampy, this is a no-equipment thing you can do yourself to take the edge off in the moment.
    Why try it
    REN12 sits on the midline of your upper belly, halfway between your navel and the base of your breastbone. In traditional Chinese medicine it is a key point for bloating, indigestion, nausea and stress-related stomach discomfort. This is traditional self-care for comfort, not a trial-proven treatment.
    Dose or use
    Find the midpoint between your navel and the bottom of your breastbone. Press gently with two fingertips, slow circles, for 1-2 minutes while breathing slowly. Repeat a few times a day, and avoid pressing on a very full stomach.
    Time to results
    Often eases discomfort within minutes; use as needed
    Key study
    Traditionally used for bloating and indigestion; this specific use has not been confirmed in controlled clinical trials.
    Caution
    This is only for mild, familiar digestive discomfort. Severe or new abdominal pain, vomiting, or symptoms that don't settle need medical attention, not acupressure. Don't press hard over a full stomach or on broken or inflamed skin.

Getting truly gluten-free — hidden gluten, cross-contact, and eating well without wheat

  1. Gluten Free Diet

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use

    The core treatment that lets the gut recover

    Why this matches
    You want to get the diet right, and this is the whole game in celiac: removing every source of gluten is what lets your intestinal lining recover and your symptoms settle.
    Why try it
    In celiac disease, gluten triggers an immune reaction that flattens the lining of your small intestine. Completely removing it is the accepted medical standard of care and the approach shown to let that lining recover. It works only if it is strict and lifelong, so the hard part is finding the hidden sources.
    Dose or use
    Cut out all wheat, barley and rye, and anything made from them, for life, not just when symptoms flare. Read every label for gluten and 'may contain' warnings. Watch cross-contact at home: separate toaster, chopping board, colander and butter, and wash shared surfaces. Choose oats labelled gluten-free only. A dietitian who knows celiac is worth one visit.
    Time to results
    Symptoms often ease within weeks; full gut-lining healing can take 6-24 months
    Key study
    A strict lifelong gluten-free diet is the universally accepted medical standard of care for celiac disease; it is the removal of the trigger rather than a supplement, so no single clinical trial is cited here.
    Caution
    Even small, occasional gluten exposure keeps the damage going, so 'mostly gluten-free' is not enough. Don't start the diet before you've been formally tested for celiac, because going gluten-free first can make the diagnosis unreliable. A poorly planned gluten-free diet can itself run short on fibre, iron and B vitamins, so replace what you cut.
  2. Iron Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    The gap celiac causes most often

    Why this matches
    You're trying to rebuild what your gut wasn't absorbing, and iron is the one to check first: it's taken up in the exact part of the bowel celiac damages, so a shortfall here is very common.
    Why try it
    The library notes iron deficiency is the most common nutritional deficiency and shows up as fatigue, weakness and pale skin. In celiac, the damaged duodenum can't absorb dietary iron well, so unexplained iron deficiency is a recognised reason to screen for celiac in the first place. Correcting a real shortfall restores energy; it is not a treatment for celiac itself.
    Dose or use
    Ask your clinician for a ferritin and blood-count test rather than guessing. If you're low, they may suggest iron-rich foods (red meat, lentils, dark leafy greens, paired with vitamin C) and, if needed, a supplement at a dose they set. Recheck levels after a few months; healing the gut on a gluten-free diet often improves absorption on its own.
    Time to results
    Energy often improves in 4-8 weeks; rebuilding stores takes 3-6 months
    Key study
    Iron's role in oxygen transport and the malabsorption of iron in celiac disease are well established; this is nutrient repletion, not a controlled-trial treatment for celiac.
    Caution
    Don't self-prescribe high-dose iron: too much causes constipation and stomach upset and is dangerous in people with haemochromatosis or iron overload. Persistent iron deficiency despite a good gluten-free diet needs a medical look for ongoing gluten exposure or other bleeding sources.
  3. Vitamin B12 (Cobalamin) Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Behind the fatigue and pins-and-needles

    Why this matches
    If your energy is flat or you get tingling and foggy thinking even when you're eating well, low B12 is a common and fixable reason in celiac, and worth checking as you rebuild.
    Why try it
    The library links B12 deficiency to impaired absorption and lists fatigue, memory trouble and numbness or tingling in the hands and feet. Untreated celiac and a poorly planned gluten-free diet both reduce B12, so topping up a genuine shortfall can lift symptoms people wrongly pin on gluten alone.
    Dose or use
    Get a B12 level checked before supplementing. If you're low, B12-rich foods (meat, fish, eggs, dairy, fortified products) plus a supplement or, in some cases, injections at the dose your clinician sets. Recheck after a few months.
    Time to results
    Fatigue can improve within weeks; nerve symptoms may take a few months
    Key study
    B12's role in nerve and red-cell function, and its malabsorption in celiac disease, are well established; correcting it is repletion, not a controlled-trial treatment for celiac.
    Caution
    Numbness or tingling that is spreading or persistent needs a clinician's assessment, not just a supplement, because untreated B12 nerve damage can become permanent. Don't assume every symptom is B12 without a test.

I'm tired, foggy or run-down — rebuild the nutrients my gut wasn't absorbing

  1. Iron Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    The gap celiac causes most often

    Why this matches
    You're trying to rebuild what your gut wasn't absorbing, and iron is the one to check first: it's taken up in the exact part of the bowel celiac damages, so a shortfall here is very common.
    Why try it
    The library notes iron deficiency is the most common nutritional deficiency and shows up as fatigue, weakness and pale skin. In celiac, the damaged duodenum can't absorb dietary iron well, so unexplained iron deficiency is a recognised reason to screen for celiac in the first place. Correcting a real shortfall restores energy; it is not a treatment for celiac itself.
    Dose or use
    Ask your clinician for a ferritin and blood-count test rather than guessing. If you're low, they may suggest iron-rich foods (red meat, lentils, dark leafy greens, paired with vitamin C) and, if needed, a supplement at a dose they set. Recheck levels after a few months; healing the gut on a gluten-free diet often improves absorption on its own.
    Time to results
    Energy often improves in 4-8 weeks; rebuilding stores takes 3-6 months
    Key study
    Iron's role in oxygen transport and the malabsorption of iron in celiac disease are well established; this is nutrient repletion, not a controlled-trial treatment for celiac.
    Caution
    Don't self-prescribe high-dose iron: too much causes constipation and stomach upset and is dangerous in people with haemochromatosis or iron overload. Persistent iron deficiency despite a good gluten-free diet needs a medical look for ongoing gluten exposure or other bleeding sources.
  2. Vitamin B12 (Cobalamin) Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Behind the fatigue and pins-and-needles

    Why this matches
    If your energy is flat or you get tingling and foggy thinking even when you're eating well, low B12 is a common and fixable reason in celiac, and worth checking as you rebuild.
    Why try it
    The library links B12 deficiency to impaired absorption and lists fatigue, memory trouble and numbness or tingling in the hands and feet. Untreated celiac and a poorly planned gluten-free diet both reduce B12, so topping up a genuine shortfall can lift symptoms people wrongly pin on gluten alone.
    Dose or use
    Get a B12 level checked before supplementing. If you're low, B12-rich foods (meat, fish, eggs, dairy, fortified products) plus a supplement or, in some cases, injections at the dose your clinician sets. Recheck after a few months.
    Time to results
    Fatigue can improve within weeks; nerve symptoms may take a few months
    Key study
    B12's role in nerve and red-cell function, and its malabsorption in celiac disease, are well established; correcting it is repletion, not a controlled-trial treatment for celiac.
    Caution
    Numbness or tingling that is spreading or persistent needs a clinician's assessment, not just a supplement, because untreated B12 nerve damage can become permanent. Don't assume every symptom is B12 without a test.
  3. Zinc Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Often low, easy to overlook

    Why this matches
    As you patch the nutrient gaps, zinc is an easy one to miss: it's absorbed in the part of the bowel celiac damages and is one of the most commonly low minerals at diagnosis.
    Why try it
    The library notes zinc deficiency arises from malabsorption and chronic illness, and shows up as hair thinning, slow-healing skin, and dulled taste and smell. Diarrhoea in active celiac also drives zinc losses, so correcting a real shortfall supports mucosal repair, immunity and taste.
    Dose or use
    Zinc-rich foods first: meat, shellfish, seeds, nuts and legumes. If signs point to a shortfall, ask your clinician about testing and a short, modest course of supplemental zinc rather than long-term high doses.
    Time to results
    Taste, skin and healing often improve over 4-8 weeks once corrected
    Key study
    Zinc's role in healing, immunity and taste, and its malabsorption in celiac disease, are well established; this is repletion, not a controlled-trial treatment for celiac.
    Caution
    Don't take high-dose zinc long term: it blocks copper absorption and can cause its own deficiency. Keep any supplement modest and time-limited unless your clinician advises otherwise.

Protecting my bones and long-term health after years of poor absorption

  1. Calcium Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Pairs with vitamin D for bone strength

    Why this matches
    Protecting your bones means getting enough calcium in as well as absorbing it, and celiac works against both, so this sits right alongside your vitamin D.
    Why try it
    The library links calcium deficiency to osteopenia and osteoporosis and weakened bones. In celiac, the damaged upper bowel absorbs calcium poorly, and many people also avoid dairy because of temporary lactose intolerance, cutting intake further. Meeting your calcium needs, with vitamin D alongside, is how you defend long-term bone density.
    Dose or use
    Aim to get calcium from food first: dairy or fortified plant milks, tinned fish with bones, tofu set with calcium, and leafy greens. If dairy is a problem or your intake is low, ask your clinician whether a calcium supplement makes sense and at what dose, taken with vitamin D.
    Time to results
    Intake improves immediately; bone density changes are measured over 1-2 years
    Key study
    Calcium's role in bone density, and its impaired absorption in celiac disease, are well established; this is repletion, not a controlled-trial treatment for celiac.
    Caution
    More is not better: high-dose calcium supplements can cause constipation and kidney stones and may not suit everyone. Food sources are safest; use supplements only to fill a genuine gap under guidance, and don't take them at the same time as iron, which blocks absorption.
  2. Vitamin D Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Fat-soluble vitamin celiac depletes

    Why this matches
    You want to protect your bones, and vitamin D is where that starts: celiac's damage to the gut makes this fat-soluble vitamin hard to absorb, and low levels directly weaken bone.
    Why try it
    The library ties vitamin D deficiency to problems with absorption and to soft, weak bones (osteomalacia in adults) and reduced bone density over time. Because celiac impairs fat absorption, low vitamin D is close to routine at diagnosis, so correcting it underpins the calcium and bone work you're trying to do.
    Dose or use
    Ask for a vitamin D blood level. If you're low, sensible sun exposure, oily fish and eggs, plus a supplement at the dose your clinician recommends. Retest after a few months to confirm you've reached a healthy level.
    Time to results
    Blood levels rebuild over 2-3 months; bone benefits accrue over the longer term
    Key study
    Vitamin D's role in calcium absorption and bone health, and its malabsorption in celiac disease, are well established; correcting it is repletion, not a controlled-trial treatment for celiac.
    Caution
    Vitamin D is fat-soluble and can build up, so don't take large doses without testing and guidance. Pair it with adequate calcium, and let your clinician steer the dose if you have kidney problems or high blood calcium.

Evidence grades describe the strength of published research for Celiac Disease, not a promise of results. Nothing here is medical advice — talk to your clinician before starting anything, especially alongside prescription medication.

Other ways people describe this

Same underlying problem, different words.

These suggestions come from our full page on Celiac Disease, where you can see every option and how it is graded. Evidence grades are explained in our methodology, and every phrasing we cover is listed under health topics.

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