Brain won't slow down, thoughts racing

Your thoughts come too fast. One idea jumps to the next before you finish the first. At night you lie in bed while your mind keeps sprinting.

Lots of things can speed up your mind. Stress, worry, and too much coffee are common ones. Some medicines and thyroid trouble can do it too.

Racing thoughts can also come in spells that last days. They may show up with high energy, fast talk, and less need for sleep. That pattern is one part of bipolar disorder, and only a doctor can sort it out.

When to see someone

See a doctor soon if your mind has raced for days, you barely sleep, and you still feel wired. Get help right away if you think of harming yourself or someone else, hear voices, or believe things your friends say are not real. A pounding heart, shaky hands, or weight loss you did not plan can point to a thyroid problem, so ask for a blood test.

Below is a list of remedies from our reviewed set for bipolar disorder. Each one carries an evidence grade, which shows how much research has looked at it, not what it will do for you. A low grade means the research is thin or missing, so talk with your doctor or pharmacist first, since some items clash with mood medicines.

Bipolar Disorder: natural remedies and the evidence behind them

14 options · 4 graded B · 10 traditional or ungraded

Where is your mood right now — which phase needs the most support?

I'm fairly stable right now — help me protect that stability

  1. Exercise

    Supported by smaller clinical studies (Evidence grade B · No traditional record)

    Lifts mood and energy when low

    Why this matches
    When depression is the dominant phase, regular moderate movement is one of the better-studied lifestyle supports for low mood — a low-risk way to lift energy.
    Why try it
    A 2025 systematic review and meta-analysis of randomized trials in bipolar disorder found structured exercise significantly improved depression and anxiety, and even helped manic symptoms, though the individual trials were small.
    Dose or use
    Aim for 30 minutes of moderate aerobic activity (walking, cycling, swimming) most days of the week.
    Time to results
    Typically 2–6 weeks
    Key study
    Systematic review and meta-analysis (2025, PMID 41676347): Meta-analysis and systematic review of the impact of different exercise intervention on emotional symptoms in patients with bipolar affective disorders.
    Caution
    Intense exercise during hypomanic or manic phases may amplify symptoms; keep sessions moderate. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
  2. Sleep Hygiene- sleep time, ritual, and temperature

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Steady sleep timing protects stability

    Why this matches
    When you're stable and want to stay that way, a fixed sleep schedule is the single highest-value daily habit in bipolar disorder — lost sleep is a known relapse trigger.
    Why try it
    This habit is about circadian regularity: going to bed and waking at the same time, a wind-down ritual, and a steady bedroom temperature — the routine most consistently recommended for keeping mood even.
    Dose or use
    Wind down and go to bed at the same time each day, ideally before 11pm, and keep a consistent, comfortable bedroom temperature at night.
    Time to results
    Typically 1–3 weeks to feel steadier
    Key study
    Circadian regularity is a standard part of bipolar self-management; framed here as routine guidance, not a tested standalone therapy.
    Caution
    A sudden drop in your need for sleep is itself an early warning of mania — if that happens, contact your care team rather than just adjusting your routine.
  3. CBT-based Mindfulness (MBSR/MBCT)

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use

    Builds awareness of mood shifts early

    Why this matches
    Mindfulness-based practice helps you notice mood changes as they happen, which is especially valuable when cycling between states.
    Why try it
    Mindfulness-based programs (MBSR/MBCT) offer a structured way to notice mood shifts early; they are used as an adjunct in bipolar care rather than a proven standalone treatment.
    Dose or use
    Follow a structured MBSR or MBCT program (typically 8 weeks); apps or group courses are widely available.
    Time to results
    Typically 6–10 weeks
    Key study
    Offered as an adjunct in bipolar care; this specific use has not been confirmed for adults in controlled clinical trials.
    Caution
    Best practiced with guidance from a qualified therapist experienced in bipolar disorder.
  4. Yin Yoga

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)

    Gentle daily practice for long-term balance

    Why this matches
    For those in a stable phase, yin yoga offers a low-intensity, grounding daily practice to support emotional resilience over time.
    Why try it
    Traditionally used to calm the nervous system and promote a sense of groundedness through slow, held poses and breathwork.
    Dose or use
    Practice for 20–45 minutes, 3–5 times per week; in-person classes or online videos are widely available.
    Time to results
    Typically 3–6 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Avoid overly stimulating practices during manic phases; yin yoga's slow pace makes it generally well-suited for most phases.

I'm mostly in a low place — flat mood, heavy fatigue, or no motivation

  1. Cognitive Behavioral Therapy

    Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple

    Structured therapy for shifting moods

    Why this matches
    When moods swing unpredictably, CBT gives you concrete tools to catch and reframe the thoughts that fuel both highs and lows — a more structured approach than mindfulness alone.
    Why try it
    CBT is a recognised psychosocial add-on in bipolar care; an individual-patient-data meta-analysis of randomized trials found psychological therapy, and CBT specifically, reduced depression scores in people with bipolar disorder.
    Dose or use
    Work with a qualified therapist, ideally one experienced in bipolar disorder; a typical course runs weekly over several months.
    Time to results
    Typically 6–12 weeks
    Key study
    Individual patient data meta-analysis (2025, PMID 40400255): The clinical efficacy of psychological interventions for bipolar depression: a systematic review and individual patient data (IPD) meta-analysis.
    Caution
    CBT complements, but does not replace, your prescribed treatment; look for a therapist familiar with bipolar disorder so the work fits your cycle. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
  2. Exercise

    Supported by smaller clinical studies (Evidence grade B · No traditional record)

    Lifts mood and energy when low

    Why this matches
    When depression is the dominant phase, regular moderate movement is one of the better-studied lifestyle supports for low mood — a low-risk way to lift energy.
    Why try it
    A 2025 systematic review and meta-analysis of randomized trials in bipolar disorder found structured exercise significantly improved depression and anxiety, and even helped manic symptoms, though the individual trials were small.
    Dose or use
    Aim for 30 minutes of moderate aerobic activity (walking, cycling, swimming) most days of the week.
    Time to results
    Typically 2–6 weeks
    Key study
    Systematic review and meta-analysis (2025, PMID 41676347): Meta-analysis and systematic review of the impact of different exercise intervention on emotional symptoms in patients with bipolar affective disorders.
    Caution
    Intense exercise during hypomanic or manic phases may amplify symptoms; keep sessions moderate. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
  3. NAC (N-Acetyl cysteine)

    Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple

    Antioxidant adjunct studied in low mood

    Why this matches
    When you're in a low phase, NAC is one of the few supplements explored as an add-on for the depressive side of bipolar disorder, working through antioxidant (glutathione) pathways in the brain.
    Why try it
    NAC raises glutathione, an antioxidant that helps protect brain cells; in a meta-analysis of bipolar-depression trials the NAC subgroup improved depressive symptoms versus placebo, though a later well-powered trial found no benefit — so results are genuinely mixed. Used only alongside your prescribed treatment.
    Dose or use
    Commonly 1,000 mg twice daily; discuss with your prescriber before adding it, especially if you take other medications.
    Time to results
    Typically 8–16 weeks
    Key study
    Meta-analysis (2022, PMID 35013098): Mitochondrial modulators in the treatment of bipolar depression: a systematic review and meta-analysis (NAC subgroup improved depressive symptoms; a later well-powered RCT was null).
    Caution
    Use only as an add-on to your prescribed care, never as a replacement. May cause mild digestive upset; check with your doctor if you take nitrates or blood thinners.
  4. Omega-3 fatty acids

    Supported by smaller clinical studies (Evidence grade B · No traditional record)

    Nutrient support for brain and mood

    Why this matches
    EPA-rich omega-3 is the form most often explored for mood support during low phases, and these fats are building blocks of brain cell membranes.
    Why try it
    EPA-rich omega-3 is the form studied for the depressive side of bipolar disorder; a meta-analysis of bipolar-depression trials found EPA outperformed placebo on clinician-rated improvement, though the effect was modest and the trials were small.
    Dose or use
    1,000–2,000 mg EPA+DHA daily with food; consult a healthcare practitioner for higher doses.
    Time to results
    Typically 4–8 weeks
    Key study
    Meta-analysis (2022, PMID 35013098): Mitochondrial modulators in the treatment of bipolar depression: a systematic review and meta-analysis.
    Caution
    May interact with blood-thinning medications; consult your doctor if on anticoagulants. Rarely, high-dose EPA has been linked to mood elevation or hypomania in bipolar disorder — start low, and use only alongside your prescribed treatment, not instead of it.
  5. Vitamin D Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Check if low vitamin D drags mood

    Why this matches
    This is the companion to the vitamin D suggestion above: it shows what a deficiency actually looks like, so the advice to get your levels tested has something concrete behind it.
    Why try it
    The library guide names low mood or depression — particularly in winter — alongside fatigue and muscle weakness as signs of low vitamin D; a simple blood test settles whether you're low.
    Dose or use
    Ask your doctor for a 25-hydroxy vitamin D blood test, especially after low-sunlight months, and correct any shortfall to the level they advise.
    Time to results
    Mood and energy shifts over 6–12 weeks once corrected
    Key study
    Educational guide to recognising low vitamin D; not a clinical treatment claim for bipolar disorder.
    Caution
    Low mood has many causes — a deficiency is only one; use this alongside, not instead of, your bipolar care.
  6. Omega-3 Fatty Acid Deficiency (EPA & DHA)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Check if you're low in omega-3

    Why this matches
    Since low phases are where omega-3 is most explored, it helps to know whether you're actually low — this shows what a shortfall looks like so you can decide if topping up makes sense.
    Why try it
    The library guide lists dry skin, fatigue and low energy among the signs of low omega-3 (EPA & DHA); checking your intake and status tells you whether supplementing is worthwhile.
    Dose or use
    Review your diet for oily fish (salmon, sardines, mackerel) 2–3 times weekly; a practitioner can test omega-3 status if you're unsure.
    Time to results
    Diet and status shifts show over weeks to months
    Key study
    Educational guide to recognising low omega-3 status; not a clinical treatment claim.
    Caution
    Deficiency signs overlap with many conditions — use this as a prompt to check with your doctor, not a diagnosis.
  7. Vitamin D

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)

    Check levels if low mood is prominent

    Why this matches
    Low vitamin D is common and is associated with low mood and fatigue; if a blood test shows you are low, correcting it removes one avoidable drag on energy and mood — most relevant when depression is the main concern.
    Why try it
    If a blood test shows you are low, correcting a vitamin D deficiency can support general energy and mood. This supports overall wellbeing rather than treating bipolar mood cycling itself.
    Dose or use
    Follow product labeling; a blood test helps determine the right dose — many people use 1,000–2,000 IU daily, but confirm with a practitioner.
    Time to results
    Typically 6–12 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Excess vitamin D can be toxic; get levels tested before supplementing at higher doses.

My moods swing unpredictably between highs and lows

  1. Cognitive Behavioral Therapy

    Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple

    Structured therapy for shifting moods

    Why this matches
    When moods swing unpredictably, CBT gives you concrete tools to catch and reframe the thoughts that fuel both highs and lows — a more structured approach than mindfulness alone.
    Why try it
    CBT is a recognised psychosocial add-on in bipolar care; an individual-patient-data meta-analysis of randomized trials found psychological therapy, and CBT specifically, reduced depression scores in people with bipolar disorder.
    Dose or use
    Work with a qualified therapist, ideally one experienced in bipolar disorder; a typical course runs weekly over several months.
    Time to results
    Typically 6–12 weeks
    Key study
    Individual patient data meta-analysis (2025, PMID 40400255): The clinical efficacy of psychological interventions for bipolar depression: a systematic review and individual patient data (IPD) meta-analysis.
    Caution
    CBT complements, but does not replace, your prescribed treatment; look for a therapist familiar with bipolar disorder so the work fits your cycle. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
  2. Sleep Hygiene- sleep time, ritual, and temperature

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Steady sleep timing protects stability

    Why this matches
    When you're stable and want to stay that way, a fixed sleep schedule is the single highest-value daily habit in bipolar disorder — lost sleep is a known relapse trigger.
    Why try it
    This habit is about circadian regularity: going to bed and waking at the same time, a wind-down ritual, and a steady bedroom temperature — the routine most consistently recommended for keeping mood even.
    Dose or use
    Wind down and go to bed at the same time each day, ideally before 11pm, and keep a consistent, comfortable bedroom temperature at night.
    Time to results
    Typically 1–3 weeks to feel steadier
    Key study
    Circadian regularity is a standard part of bipolar self-management; framed here as routine guidance, not a tested standalone therapy.
    Caution
    A sudden drop in your need for sleep is itself an early warning of mania — if that happens, contact your care team rather than just adjusting your routine.
  3. CBT-based Mindfulness (MBSR/MBCT)

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use

    Builds awareness of mood shifts early

    Why this matches
    Mindfulness-based practice helps you notice mood changes as they happen, which is especially valuable when cycling between states.
    Why try it
    Mindfulness-based programs (MBSR/MBCT) offer a structured way to notice mood shifts early; they are used as an adjunct in bipolar care rather than a proven standalone treatment.
    Dose or use
    Follow a structured MBSR or MBCT program (typically 8 weeks); apps or group courses are widely available.
    Time to results
    Typically 6–10 weeks
    Key study
    Offered as an adjunct in bipolar care; this specific use has not been confirmed for adults in controlled clinical trials.
    Caution
    Best practiced with guidance from a qualified therapist experienced in bipolar disorder.
  4. LV3 (Taichong)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Grounding point for mood swings

    Why this matches
    When your moods swing unpredictably, LV3 (Taichong) is the TCM point traditionally used for irritability and emotional lability — a grounding spot you can press yourself.
    Why try it
    In Traditional Chinese Medicine, LV3 is used to relieve tension, calm the mind and support emotional balance; it pairs naturally with HT7 as a self-care practice.
    Dose or use
    Find it on the top of the foot, in the webbing between the big and second toes; press firmly in slow circles for 1–2 minutes on each foot.
    Time to results
    May feel settling within minutes; use as needed
    Key study
    Traditionally used to ease tension and support emotional balance; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Soothing self-care only, not a substitute for your prescribed care. Avoid firm pressure if pregnant, and stop if the spot is sore.

I'm revved up — restless, racing thoughts, or sleeping much less than usual

  1. HT7 (Shenmen) - Heart 7

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Calming point for a racing mind

    Why this matches
    When you're revved up with racing thoughts or trouble sleeping, HT7 (Shenmen) is the classic calming point — pressing it is a simple, self-applied way to settle.
    Why try it
    In Traditional Chinese Medicine, HT7 is used to calm the mind, ease anxiety and support restful sleep; it is a gentle self-care practice, not a treatment for mania.
    Dose or use
    Find it on the wrist crease, pinky side of the inner forearm; press gently in slow circles for 1–2 minutes on each wrist, breathing slowly.
    Time to results
    May feel calming within minutes; use as needed
    Key study
    Traditionally used to calm the mind and support sleep; this specific use has not been confirmed in controlled clinical trials.
    Caution
    This is soothing self-care only. If you are sleeping much less than usual or feel unusually driven, contact your prescriber — those can be early signs of mania that need medical care.
  2. Magnesium Glycinate

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)

    Gentle calming support for restlessness

    Why this matches
    For general restlessness and trouble winding down, magnesium glycinate is a gentle option — it eases everyday tension and sleep-onset difficulty, but it does not treat mania.
    Why try it
    Magnesium is used to support nervous-system calm and relaxation; it may help with restlessness and settling at night.
    Dose or use
    200–400 mg magnesium glycinate in the evening; consult a healthcare practitioner for ongoing use.
    Time to results
    Typically 2–4 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    If you are sleeping much less than usual, feel unusually driven, or your thoughts are racing over days, contact your prescriber or care team promptly — these can be early signs of a manic episode that needs medical attention, not a supplement. High doses may cause loose stools; reduce if this occurs, and use caution with kidney disease.
  3. Sleep Hygiene

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)

    Sleep disruption is a key trigger to manage

    Why this matches
    During hypomanic or manic phases, lost sleep can escalate symptoms — keeping regular sleep and wake times helps anchor your daily rhythm.
    Why try it
    Regular sleep-wake timing is a standard part of bipolar self-management plans; the aim is a consistent schedule rather than a tested standalone therapy.
    Dose or use
    Keep the same wake time seven days a week, including weekends; protect a fixed wind-down window, limit screens an hour before bed, avoid caffeine after noon, and keep your room cool and dark.
    Time to results
    Typically 1–3 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Check with your healthcare provider before starting, especially if you are pregnant or breastfeeding, take prescription medication, or manage a chronic condition.
  4. Yin Yoga

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)

    Gentle daily practice for long-term balance

    Why this matches
    For those in a stable phase, yin yoga offers a low-intensity, grounding daily practice to support emotional resilience over time.
    Why try it
    Traditionally used to calm the nervous system and promote a sense of groundedness through slow, held poses and breathwork.
    Dose or use
    Practice for 20–45 minutes, 3–5 times per week; in-person classes or online videos are widely available.
    Time to results
    Typically 3–6 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Avoid overly stimulating practices during manic phases; yin yoga's slow pace makes it generally well-suited for most phases.

What kind of support would you actually stick with?

I want structured, skills-based help — therapy or mindfulness training

  1. Cognitive Behavioral Therapy

    Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple

    Structured therapy for shifting moods

    Why this matches
    When moods swing unpredictably, CBT gives you concrete tools to catch and reframe the thoughts that fuel both highs and lows — a more structured approach than mindfulness alone.
    Why try it
    CBT is a recognised psychosocial add-on in bipolar care; an individual-patient-data meta-analysis of randomized trials found psychological therapy, and CBT specifically, reduced depression scores in people with bipolar disorder.
    Dose or use
    Work with a qualified therapist, ideally one experienced in bipolar disorder; a typical course runs weekly over several months.
    Time to results
    Typically 6–12 weeks
    Key study
    Individual patient data meta-analysis (2025, PMID 40400255): The clinical efficacy of psychological interventions for bipolar depression: a systematic review and individual patient data (IPD) meta-analysis.
    Caution
    CBT complements, but does not replace, your prescribed treatment; look for a therapist familiar with bipolar disorder so the work fits your cycle. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
  2. CBT-based Mindfulness (MBSR/MBCT)

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use

    Builds awareness of mood shifts early

    Why this matches
    Mindfulness-based practice helps you notice mood changes as they happen, which is especially valuable when cycling between states.
    Why try it
    Mindfulness-based programs (MBSR/MBCT) offer a structured way to notice mood shifts early; they are used as an adjunct in bipolar care rather than a proven standalone treatment.
    Dose or use
    Follow a structured MBSR or MBCT program (typically 8 weeks); apps or group courses are widely available.
    Time to results
    Typically 6–10 weeks
    Key study
    Offered as an adjunct in bipolar care; this specific use has not been confirmed for adults in controlled clinical trials.
    Caution
    Best practiced with guidance from a qualified therapist experienced in bipolar disorder.

I'd rather move my body — exercise or gentle yoga

  1. Exercise

    Supported by smaller clinical studies (Evidence grade B · No traditional record)

    Lifts mood and energy when low

    Why this matches
    When depression is the dominant phase, regular moderate movement is one of the better-studied lifestyle supports for low mood — a low-risk way to lift energy.
    Why try it
    A 2025 systematic review and meta-analysis of randomized trials in bipolar disorder found structured exercise significantly improved depression and anxiety, and even helped manic symptoms, though the individual trials were small.
    Dose or use
    Aim for 30 minutes of moderate aerobic activity (walking, cycling, swimming) most days of the week.
    Time to results
    Typically 2–6 weeks
    Key study
    Systematic review and meta-analysis (2025, PMID 41676347): Meta-analysis and systematic review of the impact of different exercise intervention on emotional symptoms in patients with bipolar affective disorders.
    Caution
    Intense exercise during hypomanic or manic phases may amplify symptoms; keep sessions moderate. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
  2. Yin Yoga

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)

    Gentle daily practice for long-term balance

    Why this matches
    For those in a stable phase, yin yoga offers a low-intensity, grounding daily practice to support emotional resilience over time.
    Why try it
    Traditionally used to calm the nervous system and promote a sense of groundedness through slow, held poses and breathwork.
    Dose or use
    Practice for 20–45 minutes, 3–5 times per week; in-person classes or online videos are widely available.
    Time to results
    Typically 3–6 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Avoid overly stimulating practices during manic phases; yin yoga's slow pace makes it generally well-suited for most phases.

I'd rather try supplements — or find out if a nutrient gap is dragging my mood

  1. NAC (N-Acetyl cysteine)

    Supported by smaller clinical studies· Centuries of traditional use (Evidence grade B · Traditional use long-standing)Long-standing traditional staple

    Antioxidant adjunct studied in low mood

    Why this matches
    When you're in a low phase, NAC is one of the few supplements explored as an add-on for the depressive side of bipolar disorder, working through antioxidant (glutathione) pathways in the brain.
    Why try it
    NAC raises glutathione, an antioxidant that helps protect brain cells; in a meta-analysis of bipolar-depression trials the NAC subgroup improved depressive symptoms versus placebo, though a later well-powered trial found no benefit — so results are genuinely mixed. Used only alongside your prescribed treatment.
    Dose or use
    Commonly 1,000 mg twice daily; discuss with your prescriber before adding it, especially if you take other medications.
    Time to results
    Typically 8–16 weeks
    Key study
    Meta-analysis (2022, PMID 35013098): Mitochondrial modulators in the treatment of bipolar depression: a systematic review and meta-analysis (NAC subgroup improved depressive symptoms; a later well-powered RCT was null).
    Caution
    Use only as an add-on to your prescribed care, never as a replacement. May cause mild digestive upset; check with your doctor if you take nitrates or blood thinners.
  2. Omega-3 fatty acids

    Supported by smaller clinical studies (Evidence grade B · No traditional record)

    Nutrient support for brain and mood

    Why this matches
    EPA-rich omega-3 is the form most often explored for mood support during low phases, and these fats are building blocks of brain cell membranes.
    Why try it
    EPA-rich omega-3 is the form studied for the depressive side of bipolar disorder; a meta-analysis of bipolar-depression trials found EPA outperformed placebo on clinician-rated improvement, though the effect was modest and the trials were small.
    Dose or use
    1,000–2,000 mg EPA+DHA daily with food; consult a healthcare practitioner for higher doses.
    Time to results
    Typically 4–8 weeks
    Key study
    Meta-analysis (2022, PMID 35013098): Mitochondrial modulators in the treatment of bipolar depression: a systematic review and meta-analysis.
    Caution
    May interact with blood-thinning medications; consult your doctor if on anticoagulants. Rarely, high-dose EPA has been linked to mood elevation or hypomania in bipolar disorder — start low, and use only alongside your prescribed treatment, not instead of it.
  3. Vitamin D Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Check if low vitamin D drags mood

    Why this matches
    This is the companion to the vitamin D suggestion above: it shows what a deficiency actually looks like, so the advice to get your levels tested has something concrete behind it.
    Why try it
    The library guide names low mood or depression — particularly in winter — alongside fatigue and muscle weakness as signs of low vitamin D; a simple blood test settles whether you're low.
    Dose or use
    Ask your doctor for a 25-hydroxy vitamin D blood test, especially after low-sunlight months, and correct any shortfall to the level they advise.
    Time to results
    Mood and energy shifts over 6–12 weeks once corrected
    Key study
    Educational guide to recognising low vitamin D; not a clinical treatment claim for bipolar disorder.
    Caution
    Low mood has many causes — a deficiency is only one; use this alongside, not instead of, your bipolar care.
  4. Omega-3 Fatty Acid Deficiency (EPA & DHA)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Check if you're low in omega-3

    Why this matches
    Since low phases are where omega-3 is most explored, it helps to know whether you're actually low — this shows what a shortfall looks like so you can decide if topping up makes sense.
    Why try it
    The library guide lists dry skin, fatigue and low energy among the signs of low omega-3 (EPA & DHA); checking your intake and status tells you whether supplementing is worthwhile.
    Dose or use
    Review your diet for oily fish (salmon, sardines, mackerel) 2–3 times weekly; a practitioner can test omega-3 status if you're unsure.
    Time to results
    Diet and status shifts show over weeks to months
    Key study
    Educational guide to recognising low omega-3 status; not a clinical treatment claim.
    Caution
    Deficiency signs overlap with many conditions — use this as a prompt to check with your doctor, not a diagnosis.
  5. Magnesium Glycinate

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)

    Gentle calming support for restlessness

    Why this matches
    For general restlessness and trouble winding down, magnesium glycinate is a gentle option — it eases everyday tension and sleep-onset difficulty, but it does not treat mania.
    Why try it
    Magnesium is used to support nervous-system calm and relaxation; it may help with restlessness and settling at night.
    Dose or use
    200–400 mg magnesium glycinate in the evening; consult a healthcare practitioner for ongoing use.
    Time to results
    Typically 2–4 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    If you are sleeping much less than usual, feel unusually driven, or your thoughts are racing over days, contact your prescriber or care team promptly — these can be early signs of a manic episode that needs medical attention, not a supplement. High doses may cause loose stools; reduce if this occurs, and use caution with kidney disease.
  6. Vitamin D

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)

    Check levels if low mood is prominent

    Why this matches
    Low vitamin D is common and is associated with low mood and fatigue; if a blood test shows you are low, correcting it removes one avoidable drag on energy and mood — most relevant when depression is the main concern.
    Why try it
    If a blood test shows you are low, correcting a vitamin D deficiency can support general energy and mood. This supports overall wellbeing rather than treating bipolar mood cycling itself.
    Dose or use
    Follow product labeling; a blood test helps determine the right dose — many people use 1,000–2,000 IU daily, but confirm with a practitioner.
    Time to results
    Typically 6–12 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Excess vitamin D can be toxic; get levels tested before supplementing at higher doses.

Help me build steady daily rhythms — especially around sleep

  1. Sleep Hygiene- sleep time, ritual, and temperature

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Steady sleep timing protects stability

    Why this matches
    When you're stable and want to stay that way, a fixed sleep schedule is the single highest-value daily habit in bipolar disorder — lost sleep is a known relapse trigger.
    Why try it
    This habit is about circadian regularity: going to bed and waking at the same time, a wind-down ritual, and a steady bedroom temperature — the routine most consistently recommended for keeping mood even.
    Dose or use
    Wind down and go to bed at the same time each day, ideally before 11pm, and keep a consistent, comfortable bedroom temperature at night.
    Time to results
    Typically 1–3 weeks to feel steadier
    Key study
    Circadian regularity is a standard part of bipolar self-management; framed here as routine guidance, not a tested standalone therapy.
    Caution
    A sudden drop in your need for sleep is itself an early warning of mania — if that happens, contact your care team rather than just adjusting your routine.
  2. Sleep Hygiene

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · No traditional record)

    Sleep disruption is a key trigger to manage

    Why this matches
    During hypomanic or manic phases, lost sleep can escalate symptoms — keeping regular sleep and wake times helps anchor your daily rhythm.
    Why try it
    Regular sleep-wake timing is a standard part of bipolar self-management plans; the aim is a consistent schedule rather than a tested standalone therapy.
    Dose or use
    Keep the same wake time seven days a week, including weekends; protect a fixed wind-down window, limit screens an hour before bed, avoid caffeine after noon, and keep your room cool and dark.
    Time to results
    Typically 1–3 weeks
    Key study
    Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Check with your healthcare provider before starting, especially if you are pregnant or breastfeeding, take prescription medication, or manage a chronic condition.

Show me quick, hands-on calming techniques I can use anywhere

  1. HT7 (Shenmen) - Heart 7

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Calming point for a racing mind

    Why this matches
    When you're revved up with racing thoughts or trouble sleeping, HT7 (Shenmen) is the classic calming point — pressing it is a simple, self-applied way to settle.
    Why try it
    In Traditional Chinese Medicine, HT7 is used to calm the mind, ease anxiety and support restful sleep; it is a gentle self-care practice, not a treatment for mania.
    Dose or use
    Find it on the wrist crease, pinky side of the inner forearm; press gently in slow circles for 1–2 minutes on each wrist, breathing slowly.
    Time to results
    May feel calming within minutes; use as needed
    Key study
    Traditionally used to calm the mind and support sleep; this specific use has not been confirmed in controlled clinical trials.
    Caution
    This is soothing self-care only. If you are sleeping much less than usual or feel unusually driven, contact your prescriber — those can be early signs of mania that need medical care.
  2. LV3 (Taichong)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Grounding point for mood swings

    Why this matches
    When your moods swing unpredictably, LV3 (Taichong) is the TCM point traditionally used for irritability and emotional lability — a grounding spot you can press yourself.
    Why try it
    In Traditional Chinese Medicine, LV3 is used to relieve tension, calm the mind and support emotional balance; it pairs naturally with HT7 as a self-care practice.
    Dose or use
    Find it on the top of the foot, in the webbing between the big and second toes; press firmly in slow circles for 1–2 minutes on each foot.
    Time to results
    May feel settling within minutes; use as needed
    Key study
    Traditionally used to ease tension and support emotional balance; this specific use has not been confirmed in controlled clinical trials.
    Caution
    Soothing self-care only, not a substitute for your prescribed care. Avoid firm pressure if pregnant, and stop if the spot is sore.

Evidence grades describe the strength of published research for Bipolar Disorder, not a promise of results. Nothing here is medical advice — talk to your clinician before starting anything, especially alongside prescription medication.

Other ways people describe this

Same underlying problem, different words.

These suggestions come from our full page on Bipolar Disorder, where you can see every option and how it is graded. Evidence grades are explained in our methodology, and every phrasing we cover is listed under health topics.

Get it on Google PlayDownload on the App Store

Download today our free mobile application for iOS and Android

⭐️ Customer Reviews

(from verified users)

hero_img4.8
coma

This app is so cool! I've always wanted there to be a hub for all NATURAL remedies and preventative options but l've always had to do loads of digging to find the info I wanted for different natural products. HealisticMD has all the info I need in one place. It gave me various natural supplemental options for a condition I looked up, including what each remedy does and how much is usually recommended to take. It also gave me exact products I could buy for the problem I had looked up. It makes my process SO MUCH easier when I need to find non-pharmaceutical solutions to my needs.

user1

Olivia J.

tick

Verified User

rating_starts

5.0

coma

The tremendous value we have seen in this app and a lot of information and accessibility to the product that is natural and helped us finding a new ways to heal. I have came from a family filled with doctors. And we all prevented using pills as well all the pharmaceutical path and tried healing naturally The only thing we lacked of was information and research so when I saw this app, I definitely know it has a values we were looking for as well as my children enhance their immune system!!

user2

Audrey Mae.

tick

Verified User

rating_starts

5.0

coma

There is a wealth of information on the app! I recently had bloodwork done and found I was deficient in a handful of vitamins and minerals (Vitamin B12, Vitamin D, Iron, etc.) HealisticMD made it simple for me to find out what foods to eat/ supplements I needed to improve these deficiencies. It gives you so many ideas on prevention, natural health tips, where to buy the vitamins, when to take them, why, etc. I love how easy the app is to use too. I am currently working on getting pregnant. I was pleasantly surprised to find compelling data along with supplement suggestions to aid in the process, some of which my fertility doctor wasn’t even aware of. Highly recommend downloading, after all health is one our greatest gifts!

user3

Rachel

tick

Verified User

rating_starts

5.0