Panic Disorder (Panic Attacks): How is panic showing up for me right now?

Commonly suggested options include cognitive Behavioral Therapy, insitol, heart Rate Variability Training, HT7 (Shenmen) - Heart 7, acupuncture and magnesium Deficiency.

Panic Disorder (Panic Attacks): What kind of help would I actually stick with?

Commonly suggested options include cognitive Behavioral Therapy, heart Rate Variability Training, acupuncture, insitol, magnesium Deficiency and breathwork.

Panic Disorder (Panic Attacks): natural remedies and the evidence behind them

Panic disorder involves recurring, unexpected surges of intense fear or discomfort that peak within minutes, often accompanied by racing heart…

8 options · 1 graded A · 1 graded B · 2 graded C · 4 traditional or ungraded

How is panic showing up for me right now?

The worst part is the dread — fear of losing control and worrying about the next attack

Cognitive Behavioral Therapy
Supported by controlled trials (Evidence grade A · Traditional use not yet assessed)
First-line, most-evidenced therapy for panic
Why this matches
When the hardest part is the dread between attacks and the fear of losing control, CBT targets exactly that — the catastrophic thoughts and the fear-of-fear cycle that keep panic going.
Why try it
CBT is the most established psychotherapy for panic disorder, helping you reframe catastrophic interpretations of body sensations and gradually reduce the avoidance that feeds the fear.
Dose or use
Typically 8-16 weekly sessions with a trained therapist, with skills practiced between sessions.
Time to results
Often meaningful gains within 8-12 weeks
Key study
Systematic Review / Network Meta-Analysis (2023, PMID 37132646): CBT treatment delivery formats for panic disorder: a systematic review and network meta-analysis of randomised controlled trials — pooled RCT evidence supports cognitive behavioral therapy as an effective, first-line treatment for panic disorder across in-person and remote delivery formats.
Caution
Works best with a qualified therapist; self-help alone may be insufficient for severe or worsening panic. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
Insitol
Supported by smaller clinical studies (Evidence grade B · Traditional use not yet assessed)
Nutrient with panic-specific anxiety support
Why this matches
If you feel constantly wired and want a gentle daily way to take the edge off, inositol is a naturally occurring nutrient that influences the brain's calming neurotransmitter signaling.
Why try it
Small randomized trials found that high-dose myo-inositol reduced panic attacks, possibly by supporting serotonin-related signaling. The evidence comes from small studies, so it is best seen as a gentle, optional add-on rather than a stand-alone treatment.
Dose or use
Usually taken as myo-inositol powder; follow product labeling and consult a practitioner, as effective doses tend to be relatively high.
Time to results
Typically 4-6 weeks of daily use
Key study
Randomized Controlled Trial (1995, PMID 7793450): Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder — high-dose myo-inositol reduced the frequency and severity of panic attacks more than placebo; a later crossover RCT (PMID 11386498, 2001) found it comparable to the SSRI fluvoxamine. Both trials were small, so results are promising but not definitive.
Caution
May cause mild nausea or loose stools at higher doses; check with your doctor if pregnant or taking psychiatric medication.
Heart Rate Variability Training
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Directly trains heart and breath rhythm
Why this matches
If your panic shows up as a racing heart and chaotic breathing, HRV biofeedback directly targets those physical signals by teaching you to slow and regulate your breath in real time.
Why try it
Slow-paced breathing with HRV biofeedback may help retrain the nervous system's stress response, supporting steadier heart and breath rhythms when you practice it regularly.
Dose or use
Practice slow-paced breathing at about six breaths per minute using an HRV biofeedback app or device for 10-20 minutes most days; a trained practitioner can help you set it up and find your ideal pace.
Time to results
Typically 4–8 weeks of regular practice
Key study
An RCT (2023, PMID 36720404) in people with panic disorder tested slow-paced breathing with HRV biofeedback, but it measured changes in pro-inflammatory cytokines rather than panic symptoms directly, so a direct effect on symptom reduction is not established.
Caution
Best used alongside guidance from a qualified practitioner, especially if panic is severe. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
HT7 (Shenmen) - Heart 7
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Heart-meridian point to calm an anxious mind
Why this matches
If you're wired and looking to deeply calm down, HT7 ('Spirit Gate') on the wrist is the traditional point for quieting a restless, anxious mind.
Why try it
Traditionally used to calm the mind, ease nervous tension and support sleep; it's simple to press on your own whenever you feel on edge.
Dose or use
Press the point on the inner wrist crease, on the pinky side, for 1-2 minutes on each hand.
Time to results
May feel soothing within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used to calm anxiety and nervous tension; this specific use has not been confirmed in controlled clinical trials.
Caution
A gentle self-soothing aid, not a replacement for professional care for panic disorder.

I feel wired and on edge most days — I want to lower my baseline over time

Insitol
Supported by smaller clinical studies (Evidence grade B · Traditional use not yet assessed)
Nutrient with panic-specific anxiety support
Why this matches
If you feel constantly wired and want a gentle daily way to take the edge off, inositol is a naturally occurring nutrient that influences the brain's calming neurotransmitter signaling.
Why try it
Small randomized trials found that high-dose myo-inositol reduced panic attacks, possibly by supporting serotonin-related signaling. The evidence comes from small studies, so it is best seen as a gentle, optional add-on rather than a stand-alone treatment.
Dose or use
Usually taken as myo-inositol powder; follow product labeling and consult a practitioner, as effective doses tend to be relatively high.
Time to results
Typically 4-6 weeks of daily use
Key study
Randomized Controlled Trial (1995, PMID 7793450): Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder — high-dose myo-inositol reduced the frequency and severity of panic attacks more than placebo; a later crossover RCT (PMID 11386498, 2001) found it comparable to the SSRI fluvoxamine. Both trials were small, so results are promising but not definitive.
Caution
May cause mild nausea or loose stools at higher doses; check with your doctor if pregnant or taking psychiatric medication.
Acupuncture
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Traditionally used to calm and ground the nervous system
Why this matches
If you're feeling persistently wired and are looking for a hands-on way to promote deep relaxation, acupuncture offers a whole-body calming experience rooted in traditional practice.
Why try it
Traditionally used to support emotional balance and ease anxiety, acupuncture is thought to help regulate the body's stress response through specific points along energy pathways.
Dose or use
Work with a qualified, licensed practitioner; ask them how many sessions and how often are right for you.
Time to results
Typically 4–8 weeks of regular sessions
Key study
Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
Caution
Seek a licensed acupuncturist; inform them of any medications or bleeding disorders.
Magnesium Deficiency
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Low magnesium can heighten physical anxiety
Why this matches
If your panic shows up as a racing heart, muscle tension and twitchiness, low magnesium can amplify exactly this kind of nervous-system and muscle over-excitability.
Why try it
Magnesium supports healthy nerve and muscle function and the stress response, so correcting a genuine deficiency may ease physical over-arousal.
Dose or use
Ask your doctor to check your status; magnesium-rich foods or a supplement can restore levels.
Time to results
Typically several weeks once levels improve
Key study
Low magnesium is associated with heightened anxiety and neuromuscular excitability; it is a possible contributor, not a proven cause of panic disorder.
Caution
Not everyone with panic is deficient; high-dose supplements can cause diarrhea and interact with some medications, so check with your doctor.

It slams my body — racing heart, tight chest, shallow breathing, tense muscles

Breathwork
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Paced breathing calms acute panic in the moment
Why this matches
When panic takes over your breathing — fast, shallow, chest tight — structured breathwork gives you a direct way to slow your breath and switch on the body's calming response.
Why try it
Breathwork has been studied for reducing stress and promoting relaxation, and slow diaphragmatic breathing is a widely used self-help skill that may help you steady your breathing when panic starts to rise.
Dose or use
Practice slow diaphragmatic or paced breathing with longer exhales for a few minutes daily and as panic starts to rise.
Time to results
Can ease an attack within minutes; steadier with daily practice
Key study
Breathwork has been studied for reducing stress and promoting relaxation in general populations; a specific panic-disorder trial is not cited here, so a direct benefit for panic disorder is not established.
Caution
If a particular breathing pattern makes you lightheaded, ease off; not a replacement for treatment of severe panic.
Heart Rate Variability Training
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Directly trains heart and breath rhythm
Why this matches
If your panic shows up as a racing heart and chaotic breathing, HRV biofeedback directly targets those physical signals by teaching you to slow and regulate your breath in real time.
Why try it
Slow-paced breathing with HRV biofeedback may help retrain the nervous system's stress response, supporting steadier heart and breath rhythms when you practice it regularly.
Dose or use
Practice slow-paced breathing at about six breaths per minute using an HRV biofeedback app or device for 10-20 minutes most days; a trained practitioner can help you set it up and find your ideal pace.
Time to results
Typically 4–8 weeks of regular practice
Key study
An RCT (2023, PMID 36720404) in people with panic disorder tested slow-paced breathing with HRV biofeedback, but it measured changes in pro-inflammatory cytokines rather than panic symptoms directly, so a direct effect on symptom reduction is not established.
Caution
Best used alongside guidance from a qualified practitioner, especially if panic is severe. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
PC6 (Neiguan) - Pericardium 6
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Classic point for palpitations and chest tightness
Why this matches
When panic hits your body first — pounding heart, tight chest, a queasy stomach — PC6 on the inner forearm is the traditional point people press to help steady those exact sensations.
Why try it
Traditionally used in Chinese medicine to calm palpitations, nausea and anxiety; you can press it yourself for in-the-moment relief.
Dose or use
Press firmly on the inner forearm, about three finger-widths above the wrist crease, for 1-2 minutes on each arm.
Time to results
May feel calming within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used for palpitations and anxiety; this specific use has not been confirmed in controlled clinical trials.
Caution
A self-soothing aid, not a substitute for treatment; seek care if attacks are frequent or severe.
Magnesium Deficiency
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Low magnesium can heighten physical anxiety
Why this matches
If your panic shows up as a racing heart, muscle tension and twitchiness, low magnesium can amplify exactly this kind of nervous-system and muscle over-excitability.
Why try it
Magnesium supports healthy nerve and muscle function and the stress response, so correcting a genuine deficiency may ease physical over-arousal.
Dose or use
Ask your doctor to check your status; magnesium-rich foods or a supplement can restore levels.
Time to results
Typically several weeks once levels improve
Key study
Low magnesium is associated with heightened anxiety and neuromuscular excitability; it is a possible contributor, not a proven cause of panic disorder.
Caution
Not everyone with panic is deficient; high-dose supplements can cause diarrhea and interact with some medications, so check with your doctor.

When an attack hits, I need something I can do right then to ride it out

Breathwork
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Paced breathing calms acute panic in the moment
Why this matches
When panic takes over your breathing — fast, shallow, chest tight — structured breathwork gives you a direct way to slow your breath and switch on the body's calming response.
Why try it
Breathwork has been studied for reducing stress and promoting relaxation, and slow diaphragmatic breathing is a widely used self-help skill that may help you steady your breathing when panic starts to rise.
Dose or use
Practice slow diaphragmatic or paced breathing with longer exhales for a few minutes daily and as panic starts to rise.
Time to results
Can ease an attack within minutes; steadier with daily practice
Key study
Breathwork has been studied for reducing stress and promoting relaxation in general populations; a specific panic-disorder trial is not cited here, so a direct benefit for panic disorder is not established.
Caution
If a particular breathing pattern makes you lightheaded, ease off; not a replacement for treatment of severe panic.
HT7 (Shenmen) - Heart 7
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Heart-meridian point to calm an anxious mind
Why this matches
If you're wired and looking to deeply calm down, HT7 ('Spirit Gate') on the wrist is the traditional point for quieting a restless, anxious mind.
Why try it
Traditionally used to calm the mind, ease nervous tension and support sleep; it's simple to press on your own whenever you feel on edge.
Dose or use
Press the point on the inner wrist crease, on the pinky side, for 1-2 minutes on each hand.
Time to results
May feel soothing within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used to calm anxiety and nervous tension; this specific use has not been confirmed in controlled clinical trials.
Caution
A gentle self-soothing aid, not a replacement for professional care for panic disorder.
PC6 (Neiguan) - Pericardium 6
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Classic point for palpitations and chest tightness
Why this matches
When panic hits your body first — pounding heart, tight chest, a queasy stomach — PC6 on the inner forearm is the traditional point people press to help steady those exact sensations.
Why try it
Traditionally used in Chinese medicine to calm palpitations, nausea and anxiety; you can press it yourself for in-the-moment relief.
Dose or use
Press firmly on the inner forearm, about three finger-widths above the wrist crease, for 1-2 minutes on each arm.
Time to results
May feel calming within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used for palpitations and anxiety; this specific use has not been confirmed in controlled clinical trials.
Caution
A self-soothing aid, not a substitute for treatment; seek care if attacks are frequent or severe.

What kind of help would I actually stick with?

I want a trained professional in my corner — a therapist or hands-on practitioner

Cognitive Behavioral Therapy
Supported by controlled trials (Evidence grade A · Traditional use not yet assessed)
First-line, most-evidenced therapy for panic
Why this matches
When the hardest part is the dread between attacks and the fear of losing control, CBT targets exactly that — the catastrophic thoughts and the fear-of-fear cycle that keep panic going.
Why try it
CBT is the most established psychotherapy for panic disorder, helping you reframe catastrophic interpretations of body sensations and gradually reduce the avoidance that feeds the fear.
Dose or use
Typically 8-16 weekly sessions with a trained therapist, with skills practiced between sessions.
Time to results
Often meaningful gains within 8-12 weeks
Key study
Systematic Review / Network Meta-Analysis (2023, PMID 37132646): CBT treatment delivery formats for panic disorder: a systematic review and network meta-analysis of randomised controlled trials — pooled RCT evidence supports cognitive behavioral therapy as an effective, first-line treatment for panic disorder across in-person and remote delivery formats.
Caution
Works best with a qualified therapist; self-help alone may be insufficient for severe or worsening panic. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
Heart Rate Variability Training
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Directly trains heart and breath rhythm
Why this matches
If your panic shows up as a racing heart and chaotic breathing, HRV biofeedback directly targets those physical signals by teaching you to slow and regulate your breath in real time.
Why try it
Slow-paced breathing with HRV biofeedback may help retrain the nervous system's stress response, supporting steadier heart and breath rhythms when you practice it regularly.
Dose or use
Practice slow-paced breathing at about six breaths per minute using an HRV biofeedback app or device for 10-20 minutes most days; a trained practitioner can help you set it up and find your ideal pace.
Time to results
Typically 4–8 weeks of regular practice
Key study
An RCT (2023, PMID 36720404) in people with panic disorder tested slow-paced breathing with HRV biofeedback, but it measured changes in pro-inflammatory cytokines rather than panic symptoms directly, so a direct effect on symptom reduction is not established.
Caution
Best used alongside guidance from a qualified practitioner, especially if panic is severe. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
Acupuncture
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Traditionally used to calm and ground the nervous system
Why this matches
If you're feeling persistently wired and are looking for a hands-on way to promote deep relaxation, acupuncture offers a whole-body calming experience rooted in traditional practice.
Why try it
Traditionally used to support emotional balance and ease anxiety, acupuncture is thought to help regulate the body's stress response through specific points along energy pathways.
Dose or use
Work with a qualified, licensed practitioner; ask them how many sessions and how often are right for you.
Time to results
Typically 4–8 weeks of regular sessions
Key study
Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
Caution
Seek a licensed acupuncturist; inform them of any medications or bleeding disorders.

I'd rather support a calmer nervous system from within — nutrients and supplements

Insitol
Supported by smaller clinical studies (Evidence grade B · Traditional use not yet assessed)
Nutrient with panic-specific anxiety support
Why this matches
If you feel constantly wired and want a gentle daily way to take the edge off, inositol is a naturally occurring nutrient that influences the brain's calming neurotransmitter signaling.
Why try it
Small randomized trials found that high-dose myo-inositol reduced panic attacks, possibly by supporting serotonin-related signaling. The evidence comes from small studies, so it is best seen as a gentle, optional add-on rather than a stand-alone treatment.
Dose or use
Usually taken as myo-inositol powder; follow product labeling and consult a practitioner, as effective doses tend to be relatively high.
Time to results
Typically 4-6 weeks of daily use
Key study
Randomized Controlled Trial (1995, PMID 7793450): Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder — high-dose myo-inositol reduced the frequency and severity of panic attacks more than placebo; a later crossover RCT (PMID 11386498, 2001) found it comparable to the SSRI fluvoxamine. Both trials were small, so results are promising but not definitive.
Caution
May cause mild nausea or loose stools at higher doses; check with your doctor if pregnant or taking psychiatric medication.
Magnesium Deficiency
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Low magnesium can heighten physical anxiety
Why this matches
If your panic shows up as a racing heart, muscle tension and twitchiness, low magnesium can amplify exactly this kind of nervous-system and muscle over-excitability.
Why try it
Magnesium supports healthy nerve and muscle function and the stress response, so correcting a genuine deficiency may ease physical over-arousal.
Dose or use
Ask your doctor to check your status; magnesium-rich foods or a supplement can restore levels.
Time to results
Typically several weeks once levels improve
Key study
Low magnesium is associated with heightened anxiety and neuromuscular excitability; it is a possible contributor, not a proven cause of panic disorder.
Caution
Not everyone with panic is deficient; high-dose supplements can cause diarrhea and interact with some medications, so check with your doctor.

Simple techniques I can do on my own, anywhere — breathing and pressure points

Breathwork
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Paced breathing calms acute panic in the moment
Why this matches
When panic takes over your breathing — fast, shallow, chest tight — structured breathwork gives you a direct way to slow your breath and switch on the body's calming response.
Why try it
Breathwork has been studied for reducing stress and promoting relaxation, and slow diaphragmatic breathing is a widely used self-help skill that may help you steady your breathing when panic starts to rise.
Dose or use
Practice slow diaphragmatic or paced breathing with longer exhales for a few minutes daily and as panic starts to rise.
Time to results
Can ease an attack within minutes; steadier with daily practice
Key study
Breathwork has been studied for reducing stress and promoting relaxation in general populations; a specific panic-disorder trial is not cited here, so a direct benefit for panic disorder is not established.
Caution
If a particular breathing pattern makes you lightheaded, ease off; not a replacement for treatment of severe panic.
Heart Rate Variability Training
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Directly trains heart and breath rhythm
Why this matches
If your panic shows up as a racing heart and chaotic breathing, HRV biofeedback directly targets those physical signals by teaching you to slow and regulate your breath in real time.
Why try it
Slow-paced breathing with HRV biofeedback may help retrain the nervous system's stress response, supporting steadier heart and breath rhythms when you practice it regularly.
Dose or use
Practice slow-paced breathing at about six breaths per minute using an HRV biofeedback app or device for 10-20 minutes most days; a trained practitioner can help you set it up and find your ideal pace.
Time to results
Typically 4–8 weeks of regular practice
Key study
An RCT (2023, PMID 36720404) in people with panic disorder tested slow-paced breathing with HRV biofeedback, but it measured changes in pro-inflammatory cytokines rather than panic symptoms directly, so a direct effect on symptom reduction is not established.
Caution
Best used alongside guidance from a qualified practitioner, especially if panic is severe. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
HT7 (Shenmen) - Heart 7
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Heart-meridian point to calm an anxious mind
Why this matches
If you're wired and looking to deeply calm down, HT7 ('Spirit Gate') on the wrist is the traditional point for quieting a restless, anxious mind.
Why try it
Traditionally used to calm the mind, ease nervous tension and support sleep; it's simple to press on your own whenever you feel on edge.
Dose or use
Press the point on the inner wrist crease, on the pinky side, for 1-2 minutes on each hand.
Time to results
May feel soothing within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used to calm anxiety and nervous tension; this specific use has not been confirmed in controlled clinical trials.
Caution
A gentle self-soothing aid, not a replacement for professional care for panic disorder.
PC6 (Neiguan) - Pericardium 6
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Classic point for palpitations and chest tightness
Why this matches
When panic hits your body first — pounding heart, tight chest, a queasy stomach — PC6 on the inner forearm is the traditional point people press to help steady those exact sensations.
Why try it
Traditionally used in Chinese medicine to calm palpitations, nausea and anxiety; you can press it yourself for in-the-moment relief.
Dose or use
Press firmly on the inner forearm, about three finger-widths above the wrist crease, for 1-2 minutes on each arm.
Time to results
May feel calming within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used for palpitations and anxiety; this specific use has not been confirmed in controlled clinical trials.
Caution
A self-soothing aid, not a substitute for treatment; seek care if attacks are frequent or severe.

Evidence grades describe the strength of published research for Panic Disorder (Panic Attacks), not a promise of results. Nothing here is medical advice — talk to your clinician before starting anything, especially alongside prescription medication.

How is panic showing up for me right now?

The worst part is the dread — fear of losing control and worrying about the next attack

Cognitive Behavioral Therapy
Supported by controlled trials (Evidence grade A · Traditional use not yet assessed)
First-line, most-evidenced therapy for panic
Why this matches
When the hardest part is the dread between attacks and the fear of losing control, CBT targets exactly that — the catastrophic thoughts and the fear-of-fear cycle that keep panic going.
Why try it
CBT is the most established psychotherapy for panic disorder, helping you reframe catastrophic interpretations of body sensations and gradually reduce the avoidance that feeds the fear.
Dose or use
Typically 8-16 weekly sessions with a trained therapist, with skills practiced between sessions.
Time to results
Often meaningful gains within 8-12 weeks
Key study
Systematic Review / Network Meta-Analysis (2023, PMID 37132646): CBT treatment delivery formats for panic disorder: a systematic review and network meta-analysis of randomised controlled trials — pooled RCT evidence supports cognitive behavioral therapy as an effective, first-line treatment for panic disorder across in-person and remote delivery formats.
Caution
Works best with a qualified therapist; self-help alone may be insufficient for severe or worsening panic. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
Insitol
Supported by smaller clinical studies (Evidence grade B · Traditional use not yet assessed)
Nutrient with panic-specific anxiety support
Why this matches
If you feel constantly wired and want a gentle daily way to take the edge off, inositol is a naturally occurring nutrient that influences the brain's calming neurotransmitter signaling.
Why try it
Small randomized trials found that high-dose myo-inositol reduced panic attacks, possibly by supporting serotonin-related signaling. The evidence comes from small studies, so it is best seen as a gentle, optional add-on rather than a stand-alone treatment.
Dose or use
Usually taken as myo-inositol powder; follow product labeling and consult a practitioner, as effective doses tend to be relatively high.
Time to results
Typically 4-6 weeks of daily use
Key study
Randomized Controlled Trial (1995, PMID 7793450): Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder — high-dose myo-inositol reduced the frequency and severity of panic attacks more than placebo; a later crossover RCT (PMID 11386498, 2001) found it comparable to the SSRI fluvoxamine. Both trials were small, so results are promising but not definitive.
Caution
May cause mild nausea or loose stools at higher doses; check with your doctor if pregnant or taking psychiatric medication.
Heart Rate Variability Training
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Directly trains heart and breath rhythm
Why this matches
If your panic shows up as a racing heart and chaotic breathing, HRV biofeedback directly targets those physical signals by teaching you to slow and regulate your breath in real time.
Why try it
Slow-paced breathing with HRV biofeedback may help retrain the nervous system's stress response, supporting steadier heart and breath rhythms when you practice it regularly.
Dose or use
Practice slow-paced breathing at about six breaths per minute using an HRV biofeedback app or device for 10-20 minutes most days; a trained practitioner can help you set it up and find your ideal pace.
Time to results
Typically 4–8 weeks of regular practice
Key study
An RCT (2023, PMID 36720404) in people with panic disorder tested slow-paced breathing with HRV biofeedback, but it measured changes in pro-inflammatory cytokines rather than panic symptoms directly, so a direct effect on symptom reduction is not established.
Caution
Best used alongside guidance from a qualified practitioner, especially if panic is severe. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
HT7 (Shenmen) - Heart 7
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Heart-meridian point to calm an anxious mind
Why this matches
If you're wired and looking to deeply calm down, HT7 ('Spirit Gate') on the wrist is the traditional point for quieting a restless, anxious mind.
Why try it
Traditionally used to calm the mind, ease nervous tension and support sleep; it's simple to press on your own whenever you feel on edge.
Dose or use
Press the point on the inner wrist crease, on the pinky side, for 1-2 minutes on each hand.
Time to results
May feel soothing within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used to calm anxiety and nervous tension; this specific use has not been confirmed in controlled clinical trials.
Caution
A gentle self-soothing aid, not a replacement for professional care for panic disorder.

I feel wired and on edge most days — I want to lower my baseline over time

Insitol
Supported by smaller clinical studies (Evidence grade B · Traditional use not yet assessed)
Nutrient with panic-specific anxiety support
Why this matches
If you feel constantly wired and want a gentle daily way to take the edge off, inositol is a naturally occurring nutrient that influences the brain's calming neurotransmitter signaling.
Why try it
Small randomized trials found that high-dose myo-inositol reduced panic attacks, possibly by supporting serotonin-related signaling. The evidence comes from small studies, so it is best seen as a gentle, optional add-on rather than a stand-alone treatment.
Dose or use
Usually taken as myo-inositol powder; follow product labeling and consult a practitioner, as effective doses tend to be relatively high.
Time to results
Typically 4-6 weeks of daily use
Key study
Randomized Controlled Trial (1995, PMID 7793450): Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder — high-dose myo-inositol reduced the frequency and severity of panic attacks more than placebo; a later crossover RCT (PMID 11386498, 2001) found it comparable to the SSRI fluvoxamine. Both trials were small, so results are promising but not definitive.
Caution
May cause mild nausea or loose stools at higher doses; check with your doctor if pregnant or taking psychiatric medication.
Acupuncture
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Traditionally used to calm and ground the nervous system
Why this matches
If you're feeling persistently wired and are looking for a hands-on way to promote deep relaxation, acupuncture offers a whole-body calming experience rooted in traditional practice.
Why try it
Traditionally used to support emotional balance and ease anxiety, acupuncture is thought to help regulate the body's stress response through specific points along energy pathways.
Dose or use
Work with a qualified, licensed practitioner; ask them how many sessions and how often are right for you.
Time to results
Typically 4–8 weeks of regular sessions
Key study
Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
Caution
Seek a licensed acupuncturist; inform them of any medications or bleeding disorders.
Magnesium Deficiency
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Low magnesium can heighten physical anxiety
Why this matches
If your panic shows up as a racing heart, muscle tension and twitchiness, low magnesium can amplify exactly this kind of nervous-system and muscle over-excitability.
Why try it
Magnesium supports healthy nerve and muscle function and the stress response, so correcting a genuine deficiency may ease physical over-arousal.
Dose or use
Ask your doctor to check your status; magnesium-rich foods or a supplement can restore levels.
Time to results
Typically several weeks once levels improve
Key study
Low magnesium is associated with heightened anxiety and neuromuscular excitability; it is a possible contributor, not a proven cause of panic disorder.
Caution
Not everyone with panic is deficient; high-dose supplements can cause diarrhea and interact with some medications, so check with your doctor.

It slams my body — racing heart, tight chest, shallow breathing, tense muscles

Breathwork
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Paced breathing calms acute panic in the moment
Why this matches
When panic takes over your breathing — fast, shallow, chest tight — structured breathwork gives you a direct way to slow your breath and switch on the body's calming response.
Why try it
Breathwork has been studied for reducing stress and promoting relaxation, and slow diaphragmatic breathing is a widely used self-help skill that may help you steady your breathing when panic starts to rise.
Dose or use
Practice slow diaphragmatic or paced breathing with longer exhales for a few minutes daily and as panic starts to rise.
Time to results
Can ease an attack within minutes; steadier with daily practice
Key study
Breathwork has been studied for reducing stress and promoting relaxation in general populations; a specific panic-disorder trial is not cited here, so a direct benefit for panic disorder is not established.
Caution
If a particular breathing pattern makes you lightheaded, ease off; not a replacement for treatment of severe panic.
Heart Rate Variability Training
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Directly trains heart and breath rhythm
Why this matches
If your panic shows up as a racing heart and chaotic breathing, HRV biofeedback directly targets those physical signals by teaching you to slow and regulate your breath in real time.
Why try it
Slow-paced breathing with HRV biofeedback may help retrain the nervous system's stress response, supporting steadier heart and breath rhythms when you practice it regularly.
Dose or use
Practice slow-paced breathing at about six breaths per minute using an HRV biofeedback app or device for 10-20 minutes most days; a trained practitioner can help you set it up and find your ideal pace.
Time to results
Typically 4–8 weeks of regular practice
Key study
An RCT (2023, PMID 36720404) in people with panic disorder tested slow-paced breathing with HRV biofeedback, but it measured changes in pro-inflammatory cytokines rather than panic symptoms directly, so a direct effect on symptom reduction is not established.
Caution
Best used alongside guidance from a qualified practitioner, especially if panic is severe. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
PC6 (Neiguan) - Pericardium 6
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Classic point for palpitations and chest tightness
Why this matches
When panic hits your body first — pounding heart, tight chest, a queasy stomach — PC6 on the inner forearm is the traditional point people press to help steady those exact sensations.
Why try it
Traditionally used in Chinese medicine to calm palpitations, nausea and anxiety; you can press it yourself for in-the-moment relief.
Dose or use
Press firmly on the inner forearm, about three finger-widths above the wrist crease, for 1-2 minutes on each arm.
Time to results
May feel calming within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used for palpitations and anxiety; this specific use has not been confirmed in controlled clinical trials.
Caution
A self-soothing aid, not a substitute for treatment; seek care if attacks are frequent or severe.
Magnesium Deficiency
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Low magnesium can heighten physical anxiety
Why this matches
If your panic shows up as a racing heart, muscle tension and twitchiness, low magnesium can amplify exactly this kind of nervous-system and muscle over-excitability.
Why try it
Magnesium supports healthy nerve and muscle function and the stress response, so correcting a genuine deficiency may ease physical over-arousal.
Dose or use
Ask your doctor to check your status; magnesium-rich foods or a supplement can restore levels.
Time to results
Typically several weeks once levels improve
Key study
Low magnesium is associated with heightened anxiety and neuromuscular excitability; it is a possible contributor, not a proven cause of panic disorder.
Caution
Not everyone with panic is deficient; high-dose supplements can cause diarrhea and interact with some medications, so check with your doctor.

When an attack hits, I need something I can do right then to ride it out

Breathwork
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Paced breathing calms acute panic in the moment
Why this matches
When panic takes over your breathing — fast, shallow, chest tight — structured breathwork gives you a direct way to slow your breath and switch on the body's calming response.
Why try it
Breathwork has been studied for reducing stress and promoting relaxation, and slow diaphragmatic breathing is a widely used self-help skill that may help you steady your breathing when panic starts to rise.
Dose or use
Practice slow diaphragmatic or paced breathing with longer exhales for a few minutes daily and as panic starts to rise.
Time to results
Can ease an attack within minutes; steadier with daily practice
Key study
Breathwork has been studied for reducing stress and promoting relaxation in general populations; a specific panic-disorder trial is not cited here, so a direct benefit for panic disorder is not established.
Caution
If a particular breathing pattern makes you lightheaded, ease off; not a replacement for treatment of severe panic.
HT7 (Shenmen) - Heart 7
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Heart-meridian point to calm an anxious mind
Why this matches
If you're wired and looking to deeply calm down, HT7 ('Spirit Gate') on the wrist is the traditional point for quieting a restless, anxious mind.
Why try it
Traditionally used to calm the mind, ease nervous tension and support sleep; it's simple to press on your own whenever you feel on edge.
Dose or use
Press the point on the inner wrist crease, on the pinky side, for 1-2 minutes on each hand.
Time to results
May feel soothing within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used to calm anxiety and nervous tension; this specific use has not been confirmed in controlled clinical trials.
Caution
A gentle self-soothing aid, not a replacement for professional care for panic disorder.
PC6 (Neiguan) - Pericardium 6
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Classic point for palpitations and chest tightness
Why this matches
When panic hits your body first — pounding heart, tight chest, a queasy stomach — PC6 on the inner forearm is the traditional point people press to help steady those exact sensations.
Why try it
Traditionally used in Chinese medicine to calm palpitations, nausea and anxiety; you can press it yourself for in-the-moment relief.
Dose or use
Press firmly on the inner forearm, about three finger-widths above the wrist crease, for 1-2 minutes on each arm.
Time to results
May feel calming within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used for palpitations and anxiety; this specific use has not been confirmed in controlled clinical trials.
Caution
A self-soothing aid, not a substitute for treatment; seek care if attacks are frequent or severe.

What kind of help would I actually stick with?

I want a trained professional in my corner — a therapist or hands-on practitioner

Cognitive Behavioral Therapy
Supported by controlled trials (Evidence grade A · Traditional use not yet assessed)
First-line, most-evidenced therapy for panic
Why this matches
When the hardest part is the dread between attacks and the fear of losing control, CBT targets exactly that — the catastrophic thoughts and the fear-of-fear cycle that keep panic going.
Why try it
CBT is the most established psychotherapy for panic disorder, helping you reframe catastrophic interpretations of body sensations and gradually reduce the avoidance that feeds the fear.
Dose or use
Typically 8-16 weekly sessions with a trained therapist, with skills practiced between sessions.
Time to results
Often meaningful gains within 8-12 weeks
Key study
Systematic Review / Network Meta-Analysis (2023, PMID 37132646): CBT treatment delivery formats for panic disorder: a systematic review and network meta-analysis of randomised controlled trials — pooled RCT evidence supports cognitive behavioral therapy as an effective, first-line treatment for panic disorder across in-person and remote delivery formats.
Caution
Works best with a qualified therapist; self-help alone may be insufficient for severe or worsening panic. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
Heart Rate Variability Training
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Directly trains heart and breath rhythm
Why this matches
If your panic shows up as a racing heart and chaotic breathing, HRV biofeedback directly targets those physical signals by teaching you to slow and regulate your breath in real time.
Why try it
Slow-paced breathing with HRV biofeedback may help retrain the nervous system's stress response, supporting steadier heart and breath rhythms when you practice it regularly.
Dose or use
Practice slow-paced breathing at about six breaths per minute using an HRV biofeedback app or device for 10-20 minutes most days; a trained practitioner can help you set it up and find your ideal pace.
Time to results
Typically 4–8 weeks of regular practice
Key study
An RCT (2023, PMID 36720404) in people with panic disorder tested slow-paced breathing with HRV biofeedback, but it measured changes in pro-inflammatory cytokines rather than panic symptoms directly, so a direct effect on symptom reduction is not established.
Caution
Best used alongside guidance from a qualified practitioner, especially if panic is severe. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
Acupuncture
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Traditionally used to calm and ground the nervous system
Why this matches
If you're feeling persistently wired and are looking for a hands-on way to promote deep relaxation, acupuncture offers a whole-body calming experience rooted in traditional practice.
Why try it
Traditionally used to support emotional balance and ease anxiety, acupuncture is thought to help regulate the body's stress response through specific points along energy pathways.
Dose or use
Work with a qualified, licensed practitioner; ask them how many sessions and how often are right for you.
Time to results
Typically 4–8 weeks of regular sessions
Key study
Traditionally used for this condition; this specific use has not been confirmed in controlled clinical trials.
Caution
Seek a licensed acupuncturist; inform them of any medications or bleeding disorders.

I'd rather support a calmer nervous system from within — nutrients and supplements

Insitol
Supported by smaller clinical studies (Evidence grade B · Traditional use not yet assessed)
Nutrient with panic-specific anxiety support
Why this matches
If you feel constantly wired and want a gentle daily way to take the edge off, inositol is a naturally occurring nutrient that influences the brain's calming neurotransmitter signaling.
Why try it
Small randomized trials found that high-dose myo-inositol reduced panic attacks, possibly by supporting serotonin-related signaling. The evidence comes from small studies, so it is best seen as a gentle, optional add-on rather than a stand-alone treatment.
Dose or use
Usually taken as myo-inositol powder; follow product labeling and consult a practitioner, as effective doses tend to be relatively high.
Time to results
Typically 4-6 weeks of daily use
Key study
Randomized Controlled Trial (1995, PMID 7793450): Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder — high-dose myo-inositol reduced the frequency and severity of panic attacks more than placebo; a later crossover RCT (PMID 11386498, 2001) found it comparable to the SSRI fluvoxamine. Both trials were small, so results are promising but not definitive.
Caution
May cause mild nausea or loose stools at higher doses; check with your doctor if pregnant or taking psychiatric medication.
Magnesium Deficiency
Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use
Low magnesium can heighten physical anxiety
Why this matches
If your panic shows up as a racing heart, muscle tension and twitchiness, low magnesium can amplify exactly this kind of nervous-system and muscle over-excitability.
Why try it
Magnesium supports healthy nerve and muscle function and the stress response, so correcting a genuine deficiency may ease physical over-arousal.
Dose or use
Ask your doctor to check your status; magnesium-rich foods or a supplement can restore levels.
Time to results
Typically several weeks once levels improve
Key study
Low magnesium is associated with heightened anxiety and neuromuscular excitability; it is a possible contributor, not a proven cause of panic disorder.
Caution
Not everyone with panic is deficient; high-dose supplements can cause diarrhea and interact with some medications, so check with your doctor.

Simple techniques I can do on my own, anywhere — breathing and pressure points

Breathwork
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · Traditional use not yet assessed)
Paced breathing calms acute panic in the moment
Why this matches
When panic takes over your breathing — fast, shallow, chest tight — structured breathwork gives you a direct way to slow your breath and switch on the body's calming response.
Why try it
Breathwork has been studied for reducing stress and promoting relaxation, and slow diaphragmatic breathing is a widely used self-help skill that may help you steady your breathing when panic starts to rise.
Dose or use
Practice slow diaphragmatic or paced breathing with longer exhales for a few minutes daily and as panic starts to rise.
Time to results
Can ease an attack within minutes; steadier with daily practice
Key study
Breathwork has been studied for reducing stress and promoting relaxation in general populations; a specific panic-disorder trial is not cited here, so a direct benefit for panic disorder is not established.
Caution
If a particular breathing pattern makes you lightheaded, ease off; not a replacement for treatment of severe panic.
Heart Rate Variability Training
Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)
Directly trains heart and breath rhythm
Why this matches
If your panic shows up as a racing heart and chaotic breathing, HRV biofeedback directly targets those physical signals by teaching you to slow and regulate your breath in real time.
Why try it
Slow-paced breathing with HRV biofeedback may help retrain the nervous system's stress response, supporting steadier heart and breath rhythms when you practice it regularly.
Dose or use
Practice slow-paced breathing at about six breaths per minute using an HRV biofeedback app or device for 10-20 minutes most days; a trained practitioner can help you set it up and find your ideal pace.
Time to results
Typically 4–8 weeks of regular practice
Key study
An RCT (2023, PMID 36720404) in people with panic disorder tested slow-paced breathing with HRV biofeedback, but it measured changes in pro-inflammatory cytokines rather than panic symptoms directly, so a direct effect on symptom reduction is not established.
Caution
Best used alongside guidance from a qualified practitioner, especially if panic is severe. If you are having thoughts of harming yourself or of suicide, get help now — in the US call or text 988; elsewhere contact your local crisis line or emergency services.
HT7 (Shenmen) - Heart 7
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Heart-meridian point to calm an anxious mind
Why this matches
If you're wired and looking to deeply calm down, HT7 ('Spirit Gate') on the wrist is the traditional point for quieting a restless, anxious mind.
Why try it
Traditionally used to calm the mind, ease nervous tension and support sleep; it's simple to press on your own whenever you feel on edge.
Dose or use
Press the point on the inner wrist crease, on the pinky side, for 1-2 minutes on each hand.
Time to results
May feel soothing within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used to calm anxiety and nervous tension; this specific use has not been confirmed in controlled clinical trials.
Caution
A gentle self-soothing aid, not a replacement for professional care for panic disorder.
PC6 (Neiguan) - Pericardium 6
Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple
Classic point for palpitations and chest tightness
Why this matches
When panic hits your body first — pounding heart, tight chest, a queasy stomach — PC6 on the inner forearm is the traditional point people press to help steady those exact sensations.
Why try it
Traditionally used in Chinese medicine to calm palpitations, nausea and anxiety; you can press it yourself for in-the-moment relief.
Dose or use
Press firmly on the inner forearm, about three finger-widths above the wrist crease, for 1-2 minutes on each arm.
Time to results
May feel calming within minutes; effects are temporary and it is not a treatment for panic disorder
Key study
Traditionally used for palpitations and anxiety; this specific use has not been confirmed in controlled clinical trials.
Caution
A self-soothing aid, not a substitute for treatment; seek care if attacks are frequent or severe.

How is panic showing up for me right now?

The worst part is the dread — fear of losing control and worrying about the next attack

HT7 (Shenmen) - Heart 7

I feel wired and on edge most days — I want to lower my baseline over time

Magnesium Deficiency

It slams my body — racing heart, tight chest, shallow breathing, tense muscles

PC6 (Neiguan) - Pericardium 6

Magnesium Deficiency

When an attack hits, I need something I can do right then to ride it out

HT7 (Shenmen) - Heart 7

PC6 (Neiguan) - Pericardium 6

What kind of help would I actually stick with?

I want a trained professional in my corner — a therapist or hands-on practitioner

I'd rather support a calmer nervous system from within — nutrients and supplements

Magnesium Deficiency

Simple techniques I can do on my own, anywhere — breathing and pressure points

HT7 (Shenmen) - Heart 7

PC6 (Neiguan) - Pericardium 6

Natural remedies for Panic Disorder (Panic Attacks)

How people describe Panic Disorder (Panic Attacks)

The evidence behind Panic Disorder (Panic Attacks), in one page

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5.0

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How is panic showing up for me right now?

The worst part is the dread — fear of losing control and worrying about the next attack

HT7 (Shenmen) - Heart 7

I feel wired and on edge most days — I want to lower my baseline over time

Magnesium Deficiency

It slams my body — racing heart, tight chest, shallow breathing, tense muscles

PC6 (Neiguan) - Pericardium 6

Magnesium Deficiency

When an attack hits, I need something I can do right then to ride it out

HT7 (Shenmen) - Heart 7

PC6 (Neiguan) - Pericardium 6

What kind of help would I actually stick with?

I want a trained professional in my corner — a therapist or hands-on practitioner

I'd rather support a calmer nervous system from within — nutrients and supplements

Magnesium Deficiency

Simple techniques I can do on my own, anywhere — breathing and pressure points

HT7 (Shenmen) - Heart 7

PC6 (Neiguan) - Pericardium 6

Natural remedies for Panic Disorder (Panic Attacks)

How people describe Panic Disorder (Panic Attacks)

The evidence behind Panic Disorder (Panic Attacks), in one page