Educational information, not medical advice.See how evidence is graded

Senna

Best studied for: Short-term constipation; Constipation from opioid painkillers; Bowel clear-out under medical direction.

Home

What is Senna? Senna is a herbal laxative made from the dried leaves and pods of Senna alexandrina. People take it for short-term relief of constipation. It does work, and human trials back that. In France the herb was called séné, and it has a long place in European folk practice. But it is more than folklore now. Senna is a licensed over-the-counter medicine in the UK, the US and much of Europe. Traditional standing is not proof that something works, and it is not proof that it is safe. Senna is unusual: the effect is proven, but the risks are real. Overuse can cause cramps, fluid loss and low potassium. How does Senna work? The laxative effect of senna is well established in people. The plant contains sennosides, which pass through the small bowel unchanged. Bacteria in the colon turn sennosides into rhein anthrone, the active form. This acts on the lining of the large bowel. It speeds up the muscle waves and pulls water into the stool. The result is a softer stool and a strong urge to go. Most people respond 6 to 12 hours after a dose. That delay is why labels suggest taking it at night. The old folk idea that senna "cleans toxins out" is not supported. It moves the bowel. It does not detoxify the body. Long use can stain the colon lining dark brown, a change called melanosis coli. It is harmless and fades after stopping. Whether long use weakens the bowel muscle is still argued, and the evidence is weak either way. What forms does Senna come in? Senna is sold both as a licensed over-the-counter laxative and as a loose herb. Tablets and capsules are the most common form. The label states the sennoside content, so the strength is known. Syrups and liquid drops are used when tablets are hard to swallow. Many are made for children and are meant for use on medical advice. Dried leaf and pod are sold loose for tea, sometimes blended with fennel or anise. Strength varies a lot from cup to cup, which makes the amount hard to judge. Senna also hides inside other products. "Bowel cleanse" blends, slimming teas and some "flat tummy" teas contain it, often without making the laxative action clear. Where it comes from: Senna entered European medicine through Arabic physicians, who wrote about it from around the 9th century. Traders carried the dried leaf and pod west along Mediterranean routes. By the late Middle Ages it was listed in European pharmacopoeias (official drug lists). French texts named it séné. Village healers and apothecaries used it as a purge for "sluggish" bowels. It also appeared in spring "cleansing" routines, often mixed with liquorice or anise to soften the griping. In the 20th century senna moved from the folk shelf to the pharmacy shelf. It became one of the first herbs accepted as a standard over-the-counter drug.

Helps

What does Senna help with? Short-term constipation: This is the use with real human evidence behind it. Trials show senna increases how often people pass stool, compared with a dummy pill. It is meant for occasional, short-term use. It does not treat the cause of constipation. Fibre, fluids and movement remain the first steps for most people. Senna is a prod, not a fix. Constipation caused by opioid painkillers: Strong painkillers slow the bowel badly, and senna is a standard option for that. Hospital and hospice teams use it widely, often alongside a stool softener. The trial evidence here is modest but points the same way. This use is best set up by the team managing your pain medicine. Constipation in palliative care: Senna appears in many palliative care protocols for constipation. Reviews find it helpful, though the studies are small. Doses and combinations in this setting are chosen by a clinician. It is not a self-care decision. Bowel clear-out before a scan or colonoscopy: Some clearing regimes before a colonoscopy include senna. This is prescribed and timed by the hospital. Never build your own prep from an over-the-counter product. The timing and fluid balance matter. Claimed use for detox and weight loss: There is no good evidence that senna causes real weight loss. Any drop on the scale is water and stool weight, and it comes straight back. Slimming teas that rely on senna can cause cramps, dehydration and low potassium. Regular use for this purpose is a known route into laxative misuse. If you are using laxatives to control your weight, that is worth raising with a doctor.

Quick Facts

  • What it is: A plant-based stimulant laxative from the leaves and pods of Senna alexandrina, used for short-term constipation.
  • Main uses: Short-term constipation, Constipation from opioid painkillers, Bowel clear-out under medical direction
  • Active ingredients: Sennosides A and B, Sennosides C and D, Rhein, Aloe-emodin
  • Forms: Tablets, Capsules, Syrup and liquid drops, Dried leaf and pod for tea, Combined "cleanse" and slimming teas
  • Time to effect: Usually 6 to 12 hours; often overnight.
  • Side effects: Cramps and loose stools are common; repeated use can cause fluid loss and low potassium.
  • Pregnancy & breastfeeding: Avoid unless your clinician advises otherwise.

Educational information, not medical advice — ask your doctor or midwife.

What is Senna?

Senna is a herbal laxative made from the dried leaves and pods of Senna alexandrina. People take it for short-term relief of constipation. It does work, and human trials back that.

In France the herb was called séné, and it has a long place in European folk practice. But it is more than folklore now. Senna is a licensed over-the-counter medicine in the UK, the US and much of Europe.

Traditional standing is not proof that something works, and it is not proof that it is safe. Senna is unusual: the effect is proven, but the risks are real. Overuse can cause cramps, fluid loss and low potassium.

How does Senna work?

The laxative effect of senna is well established in people. The plant contains sennosides, which pass through the small bowel unchanged.

Bacteria in the colon turn sennosides into rhein anthrone, the active form. This acts on the lining of the large bowel. It speeds up the muscle waves and pulls water into the stool.

The result is a softer stool and a strong urge to go. Most people respond 6 to 12 hours after a dose. That delay is why labels suggest taking it at night.

The old folk idea that senna "cleans toxins out" is not supported. It moves the bowel. It does not detoxify the body.

Long use can stain the colon lining dark brown, a change called melanosis coli. It is harmless and fades after stopping. Whether long use weakens the bowel muscle is still argued, and the evidence is weak either way.

What forms does Senna come in?

Senna is sold both as a licensed over-the-counter laxative and as a loose herb.

Tablets and capsules are the most common form. The label states the sennoside content, so the strength is known.

Syrups and liquid drops are used when tablets are hard to swallow. Many are made for children and are meant for use on medical advice.

Dried leaf and pod are sold loose for tea, sometimes blended with fennel or anise. Strength varies a lot from cup to cup, which makes the amount hard to judge.

Senna also hides inside other products. "Bowel cleanse" blends, slimming teas and some "flat tummy" teas contain it, often without making the laxative action clear.

Where it comes from:

Senna entered European medicine through Arabic physicians, who wrote about it from around the 9th century. Traders carried the dried leaf and pod west along Mediterranean routes.

By the late Middle Ages it was listed in European pharmacopoeias (official drug lists). French texts named it séné. Village healers and apothecaries used it as a purge for "sluggish" bowels.

It also appeared in spring "cleansing" routines, often mixed with liquorice or anise to soften the griping. In the 20th century senna moved from the folk shelf to the pharmacy shelf. It became one of the first herbs accepted as a standard over-the-counter drug.

Who should avoid Senna?

  • Do not use if you have, or may have, a blocked bowel (bowel obstruction).
  • Do not use if you have belly pain of unknown cause, especially with fever or vomiting.
  • Never use if appendicitis is possible.
  • Do not use if you have Crohn's disease or ulcerative colitis (long-term inflammation of the bowel).
  • Do not use if you are badly dehydrated or have been told you have low potassium.
  • Do not use if you take digoxin (a heart medicine) unless your doctor says it is fine.
  • Do not use if you take a water pill (diuretic) or steroid tablets, without asking a pharmacist first.
  • Do not give it to a child under 12 unless a doctor tells you to.
  • Do not use in pregnancy unless your doctor or midwife has approved it.
  • Do not use while breastfeeding without asking a health professional.
  • Do not use it for more than about a week without medical advice.
  • Do not use it for weight loss or "detox".

When should you see a doctor?

Stop and see a doctor if any of these happen.

You get no bowel movement at all after using it, or you have rectal bleeding or black stools. You have severe cramps, ongoing vomiting, or a swollen, tender belly.

You feel weak, dizzy or shaky, or your heart feels like it is skipping or racing. These can signal fluid loss or low potassium.

Also book an appointment if constipation lasts more than two weeks, if it is new for you and you are over 50, or if it comes with weight loss you did not plan.

Is Senna legal where you live?

In the UK, the US and most of the EU, senna is a legal over-the-counter laxative medicine. It is also sold as a herbal tea and in food supplements. Rules on labelling and warnings vary by country.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

The evidence behind this remedy, in one page

What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.

One email with the summary. We'll also send a short weekly evidence update — unsubscribe any time.