Quillay is the inner bark of a Chilean evergreen tree, Quillaja saponaria, also called soap bark. The bark is full of saponins, natural soap-like compounds that foam when you shake them in water. People in Chile have long used it as a body and hair wash, and as a folk cough remedy.
Most quillay harvested today does not go into herbal medicine at all. Its extract is a legal foaming agent in soft drinks and cocktail mixers, and a purified part of it, called QS-21, is an ingredient in some licensed vaccines.
Evidence verdict: quillay has a long, well-documented history of use in Chile, but almost no human trial evidence supports the ways it is sold as a herbal remedy. Traditional use means a plant has been valued for generations. It does not prove the plant works, and it does not prove the plant is safe.
The short answer is that nobody has shown, in people, how quillay works as a medicine.
Saponins act like a natural detergent. They break up oils and grease, which is why the bark foams and why it has been used to wash hair and skin. That part is simple chemistry, not a medical effect.
The old cough idea is that swallowing a bitter, slightly irritating saponin tea makes the stomach lining complain, and the body answers by producing thinner mucus in the airways. This is a theory borrowed from other saponin plants. It has not been tested properly in people taking quillay.
Saponins can also poke holes in cell membranes, the outer skin of a cell. In the lab this helps vaccine makers get an immune response going. It is also the reason large amounts taken by mouth can damage the gut lining and, if absorbed, red blood cells.
Quillay is sold mainly as dried inner bark, in strips or chips. It is simmered in water to make a foaming wash or a weak tea. You will also see liquid extracts, tinctures and dried powdered extracts.
Most quillay made today is not sold as a herbal medicine. It goes into shampoos, soaps, foaming drinks, film coatings and animal feed. The purified saponin QS-21 is made under pharmaceutical control for use in vaccines, and is never sold to the public.
Quillay belongs to the Mapuche people of central Chile, and the name comes from the Mapudungun word for washing. The bark was the everyday soap and hair wash long before European contact.
Use spread through Chile, Peru, Bolivia and into Latin American folk practice, where a bark decoction was also taken for stubborn chest coughs. Nineteenth-century traders shipped the bark to Europe as a soap substitute and a foaming agent.
See a doctor the same day if you get bad stomach pain, repeated vomiting or diarrhoea that will not stop after using quillay.
Get medical help straight away if your skin or the whites of your eyes turn yellow, your urine turns dark, you feel very tired and unwell, or you become short of breath, dizzy or unusually pale. These can be signs of liver damage or of red blood cells breaking apart.
Call emergency services if you have chest tightness, wheezing, swelling of the lips or face, or trouble breathing after contact with the bark or its dust.
Also see a doctor if a cough lasts more than three weeks, brings up blood, or comes with fever or weight loss. Do not treat that with a herb.
Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
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