Educational information, not medical advice.See how evidence is graded

Allium sativum

Best studied for: High blood pressure; Raised cholesterol; General heart health; Claimed support during colds.

Home

What is Allium sativum? What is garlic, and what do people take it for? Garlic is the bulb of Allium sativum, a food plant grown worldwide. People eat it as food and also take it as pills, powders and oils for the heart, blood pressure and colds. The bulb splits into cloves. Crushing or chopping a clove releases its smell and its main active chemicals. Cooking changes those chemicals, so a hot meal and a supplement are not the same thing. Here is the honest verdict. Garlic supplements give a small, real drop in blood pressure in people whose blood pressure is high. Effects on cholesterol look small, and claims about colds, flu and cancer rest on weak or indirect evidence. Garlic has been used for thousands of years. Long use is not proof that something works, and it is not proof that it is safe. Both have to be tested, and that point is made once here rather than repeated in every section below. How does Allium sativum work? How is garlic thought to work? The leading idea involves sulfur compounds released when a clove is cut or crushed. Whole cloves hold alliin and an enzyme kept apart from it. Damage to the clove mixes them. That reaction makes allicin, which breaks down fast into other sulfur compounds. In cell and animal studies, these compounds appear to relax blood vessels and to slow the clumping of platelets, the cells that help blood clot. In test tubes they also slow the growth of some bacteria and fungi. Whether that happens inside the body at normal doses is not established. For blood pressure, the effect itself is measured in people, not just in the lab. Human trials show a modest fall. The exact chemical path behind that fall is still debated. What forms does Allium sativum come in? What forms does garlic come in? Both food and supplement forms are sold widely. Common forms: Fresh raw cloves, crushed or chopped. Cooked garlic in food. Dried garlic powder tablets, often coated to pass the stomach. Aged garlic extract, made by storing sliced garlic in alcohol for months. Garlic oil capsules, made by steam distilling or soaking. Odour-reduced or "odourless" tablets. The forms are not equal. Most blood pressure trials used dried powder tablets or aged garlic extract. Raw garlic has been tested far less in formal trials. Garlic is also sold as an essential oil for the skin. Undiluted garlic or garlic oil on skin can cause burns and blisters. Where it comes from: How was garlic used in the past? It was one of the most widely used plants in old medicine and in cooking. Writers in ancient Egypt, Greece, India and China recorded it. It was given to workers and soldiers for strength. Healers applied it to wounds and used it for coughs, worms and stomach complaints. In European folk use it was linked with the chest and the blood. During both World Wars, garlic preparations were used on wounds when other supplies ran short. These records show standing, not proof. They are listed here as history, not as a reason to treat yourself.

Helps

What does Allium sativum help with? High blood pressure: This is the strongest use. Pooled analyses of trials show garlic supplements lower the top number by roughly 5 to 8 points in people with raised blood pressure. The effect is small but repeated across studies. It is smaller than a standard blood pressure drug. Garlic is not a replacement for prescribed medicine. Raised cholesterol: Tradition tied garlic to "cleansing the blood". Trials show a small drop in total cholesterol in some people, and no clear change in others. Results differ by product and trial quality. The average benefit is modest at best. Do not expect it to replace a statin or a diet change. Common cold and other mild infections: Folk use treated garlic as an infection remedy. In test tubes, garlic compounds slow many bacteria, viruses and fungi. Human evidence is thin. One small trial suggested fewer colds with daily garlic, but it was low quality and has not been firmly repeated. Reviewers call this evidence insufficient. Hardening of the arteries: Some trials using aged garlic extract report slower build-up of calcium in heart arteries. These studies are small and often funded by product makers. Whether garlic lowers heart attacks or strokes has not been shown. That outcome has not been properly tested. Cancer prevention (claimed, not shown): Population surveys have linked diets high in garlic and onions with lower rates of some stomach and bowel cancers. These surveys cannot show cause. No trial has shown that garlic or garlic supplements prevent cancer. Treat this claim as unproven.

Allium sativum

Quick Facts

  • What it is: The bulb of Allium sativum, eaten as food and taken as a supplement for blood pressure and heart health.
  • Main uses: High blood pressure, Raised cholesterol, General heart health, Claimed support during colds
  • Active ingredients: Alliin, Allicin, Diallyl disulfide, S-allyl cysteine
  • Forms: Fresh cloves, Dried powder tablets, Aged garlic extract, Garlic oil capsules
  • Time to effect: Weeks, usually 8 to 12, for blood pressure changes.
  • Side effects: Smell, heartburn and gas are common; the main real risk is easier bleeding.
  • Pregnancy & breastfeeding: Avoid in pregnancy and while breastfeeding.

Educational information, not medical advice — ask your doctor or midwife.

What is Allium sativum?

What is garlic, and what do people take it for? Garlic is the bulb of Allium sativum, a food plant grown worldwide. People eat it as food and also take it as pills, powders and oils for the heart, blood pressure and colds.

The bulb splits into cloves. Crushing or chopping a clove releases its smell and its main active chemicals. Cooking changes those chemicals, so a hot meal and a supplement are not the same thing.

Here is the honest verdict. Garlic supplements give a small, real drop in blood pressure in people whose blood pressure is high. Effects on cholesterol look small, and claims about colds, flu and cancer rest on weak or indirect evidence.

Garlic has been used for thousands of years. Long use is not proof that something works, and it is not proof that it is safe. Both have to be tested, and that point is made once here rather than repeated in every section below.

How does Allium sativum work?

How is garlic thought to work? The leading idea involves sulfur compounds released when a clove is cut or crushed.

Whole cloves hold alliin and an enzyme kept apart from it. Damage to the clove mixes them. That reaction makes allicin, which breaks down fast into other sulfur compounds.

In cell and animal studies, these compounds appear to relax blood vessels and to slow the clumping of platelets, the cells that help blood clot. In test tubes they also slow the growth of some bacteria and fungi. Whether that happens inside the body at normal doses is not established.

For blood pressure, the effect itself is measured in people, not just in the lab. Human trials show a modest fall. The exact chemical path behind that fall is still debated.

What forms does Allium sativum come in?

What forms does garlic come in? Both food and supplement forms are sold widely.

Common forms:

Fresh raw cloves, crushed or chopped.

Cooked garlic in food.

Dried garlic powder tablets, often coated to pass the stomach.

Aged garlic extract, made by storing sliced garlic in alcohol for months.

Garlic oil capsules, made by steam distilling or soaking.

Odour-reduced or "odourless" tablets.

The forms are not equal. Most blood pressure trials used dried powder tablets or aged garlic extract. Raw garlic has been tested far less in formal trials.

Garlic is also sold as an essential oil for the skin. Undiluted garlic or garlic oil on skin can cause burns and blisters.

Where it comes from:

How was garlic used in the past? It was one of the most widely used plants in old medicine and in cooking.

Writers in ancient Egypt, Greece, India and China recorded it. It was given to workers and soldiers for strength. Healers applied it to wounds and used it for coughs, worms and stomach complaints.

In European folk use it was linked with the chest and the blood. During both World Wars, garlic preparations were used on wounds when other supplies ran short.

These records show standing, not proof. They are listed here as history, not as a reason to treat yourself.

Who should avoid Allium sativum?

  • Do not take garlic supplements if you are on warfarin or another blood thinner (anticoagulant) unless your doctor agrees and monitors you.
  • Do not take garlic supplements if you take saquinavir or other HIV medicines, because garlic can lower the drug level in your blood.
  • Do not take garlic supplements if you take ciclosporin or tacrolimus after a transplant.
  • Stop garlic supplements before planned surgery or dental surgery, and tell the surgeon; usually they ask for one to two weeks.
  • Do not use garlic supplements if you have a bleeding disorder such as haemophilia.
  • Never leave crushed raw garlic taped or held on the skin, as it can cause chemical burns and blisters.
  • Do not swallow garlic essential oil.
  • Do not give garlic supplements to babies or young children.
  • Avoid garlic supplements if you are pregnant or breastfeeding; garlic as food in meals is fine.
  • Do not use garlic if you have had an allergic reaction to garlic, onion or leek.

When should you see a doctor?

When should you see a doctor? Stop garlic supplements and get medical advice if you notice any of these.

Unusual bruising, nosebleeds, bleeding gums, or blood in urine or stool.

Black, tar-like stools or vomiting that looks like coffee grounds; treat this as urgent.

Severe or lasting stomach pain or heartburn.

Dizziness or fainting, which may mean low blood pressure (hypotension).

Shaking, sweating or confusion if you take diabetes medicine; this may be low blood sugar.

Burns or blisters where garlic touched your skin.

Call emergency services for swelling of the lips, tongue or throat, or trouble breathing after taking garlic.

Also see your doctor before using garlic for blood pressure instead of prescribed medicine. Never stop a prescribed drug on your own.

Is Allium sativum legal where you live?

In the UK, EU, US, Canada and Australia, garlic is an ordinary food. Garlic supplements are sold as food supplements or dietary supplements, not as licensed medicines, so they are not checked for strength or purity the way drugs are.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

The evidence behind this remedy, in one page

What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.

One email with the summary. We'll also send a short weekly evidence update — unsubscribe any time.