African yellow wood is the bark of Enantia chlorantha, a forest tree of West and Central Africa. Healers there used the bright yellow inner bark as a bitter tonic. The Yoruba name is awopa.
Most of it is sold as dried bark, bark powder, capsules or dark bitter mixes. The yellow colour comes from a group of plant alkaloids. These same compounds give the bark its very bitter taste.
Here is the honest verdict. Nearly all the research sits in test tubes and in rodents. There are no good human trials, so no health benefit is proven in people.
Long use in a tradition tells you the plant mattered to people. It does not tell you the plant works, and it does not tell you it is safe.
No one has shown what this bark does inside the human body. What follows is lab and animal work only.
The bark is rich in protoberberine alkaloids, a bitter yellow group of plant compounds. In test tubes, these slow the growth of the malaria parasite. Whether that happens in a person taking the bark is not known.
In rodents, bark extracts have lowered blood sugar and reduced some markers of liver stress. Rodent results often fail to repeat in people. Treat them as a question, not an answer.
Bitter plants like this one are also thought to boost saliva, stomach juices and bile flow. That idea is old and plausible. It has not been tested well in people for this bark.
Berberine, a close relative of the main alkaloids here, is known to block some drug-handling enzymes in the gut and liver. That is why the drug cautions on this page matter.
You will meet it in a few forms:
- Loose dried bark or bark chips, for boiling - Bark powder, loose or in capsules - Tinctures and alcohol extracts - Blended "bitters" sold in bottles, often with other herbs - Topical pastes and washes, in home use
Blended bitters are the hardest to judge. They often hide several herbs and sometimes added alcohol. The label may not list real amounts.
Bark of this tree held a steady place in West and Central African healing. Records from Nigeria, Cameroon and Ghana describe its use across many groups.
Healers boiled the bark and gave the bitter liquid for fever and malaria. They also used it for yellow eyes and skin, for stomach complaints and for wounds.
The bark doubled as a yellow dye for cloth and wood. Market sellers in Nigeria still stock it under names such as awopa and dokita igbo.
This page reports that history. It does not suggest you copy it at home.
Stop taking it and see a doctor the same day if you notice:
- Yellow eyes or yellow skin - Dark urine or pale stools - Pain under your right ribs - Nausea and vomiting that will not settle - Unusual tiredness or loss of appetite - Easy bruising or bleeding gums
Go to an emergency department now if you have a fever with chills, confusion, fits, trouble breathing or you cannot keep fluids down. Fever in a malaria area is an emergency until a test says otherwise.
If you have diabetes and feel shaky, sweaty or confused, check your blood sugar and treat a low at once.
In the United States, the United Kingdom and the European Union, it is not approved as a medicine. Where sold, it is sold as a food supplement, which means no proof of benefit is needed. In Nigeria, some bark-based bitters are registered with NAFDAC as herbal products, which checks the maker, not the claims.
Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
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